DRSC/TRiP Functional Genomics Resources

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Protein Alignment trol and LanA

DIOPT Version :10

Sequence 1:NP_001401049.1 Gene:trol / 45320 FlyBaseID:FBgn0284408 Length:4489 Species:Drosophila melanogaster
Sequence 2:NP_476617.1 Gene:LanA / 38723 FlyBaseID:FBgn0002526 Length:3712 Species:Drosophila melanogaster


Alignment Length:4479 Identity:914/4479 - (20%)
Similarity:1403/4479 - (31%) Gaps:1605/4479 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   576 YQCRD---GTRCISVSQQCDGHSDCSDGDDEEHCDGSGYDSEECRFDEFHCG--TGECIP----- 630
            |..:|   |.||:     |:||:|..|..|.:    |......||.....||  ..||.|     
  Fly   262 YSIKDISIGGRCM-----CNGHADTCDVKDPK----SPVRILACRCQHHTCGIQCNECCPGFEQK 317

  Fly   631 -MRQVCD----NIYDCNDYSDEVNCVEGEEEDRVGIPI---GHQPWRPASKHDDWLHEMDTSEYQ 687
             .||..:    |...||.:.....|...||.:|.|:.:   ||                      
  Fly   318 KWRQNTNARPFNCEPCNCHGHSNECKYDEEVNRKGLSLDIHGH---------------------- 360

  Fly   688 VYQPSNVYEKANSQ------NPCASNQFR-----CTTSNVCIPLHLRCDGFY---HCNDMSDEKS 738
             |....|.:.....      |.|....:|     ...::||.|  .:||.|:   ||.:.:....
  Fly   361 -YDGGGVCQNCQHNTVGINCNKCKPKYYRPKGKHWNETDVCSP--CQCDYFFSTGHCEEETGNCE 422

  Fly   739 CEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTV 803
            |.                                                               
  Fly   423 CR--------------------------------------------------------------- 424

  Fly   804 GVANSPPQTCLENIEFACHNRDCISIESVCD-------GIPDCGRNEDEDDALCKCSG-DKYKCQ 860
             .|..||.                     ||       |.|:|...|      |..:| :.|.|:
  Fly   425 -AAFQPPS---------------------CDSCAYGYYGYPNCRECE------CNLNGTNGYHCE 461

  Fly   861 RGGGCIPKSQVCDGKPQCHDRSDESACHLHGRLNKTRLGVKCLESQYQCGDG--------SCISG 917
            ...|           .||       .|.::      ..|..|    .||.:|        :|   
  Fly   462 AESG-----------QQC-------PCKIN------FAGAYC----KQCAEGYYGFPECKAC--- 495

  Fly   918 YKRCNGI----HDCADASDEYNCIYDYEDTYDTDPNNNPLNECDILEFEC-----DYSQCLPLEK 973
              .||.|    :||...:.|..|:.::..           :.|:    .|     :|..|     
  Fly   496 --ECNKIGSITNDCNVTTGECKCLTNFGG-----------DNCE----RCKHGYFNYPTC----- 538

  Fly   974 KCDGYADCEDMSDELE-CQSYTDHCLESEF----ECDSYCLPRDQLCNGI---PNCQDGSDERNC 1030
               .|.||::...|.| |...:..|:..|.    .||. |||      |.   |:|:    ..||
  Fly   539 ---SYCDCDNQGTESEICNKQSGQCICREGFGGPRCDQ-CLP------GFYNYPDCK----PCNC 589

  Fly  1031 TFCREDAYLC-NTGECVADNQRCNGIADCADGSDERHC----ARIYCPPNKLACNGTC---VSRR 1087
            :.....|..| |||:|           :|.:....:.|    |..|..|:.|.|:  |   .|:.
  Fly   590 SSTGSSAITCDNTGKC-----------NCLNNFAGKQCTLCTAGYYSYPDCLPCH--CDSHGSQG 641

  Fly  1088 IKCDGIRDCL-----DGYDEMYCPETNNHYPT-QNVN-----VIRPKLGPNPIP----------- 1130
            :.|:....||     ||.....|.|...::|: ::.|     ||....|...:|           
  Fly   642 VSCNSDGQCLCQPNFDGRQCDSCKEGFYNFPSCEDCNCDPAGVIDKFAGCGSVPVGELCKCKERV 706

  Fly  1131 -----KSCRPHEWQCANLECIDSSLQCNEIKDC-SDGSDEELSVCFGTATTRLKPSDCSPEQFYC 1189
                 ..|:|..|   ||. |.::..| ||.|| :||:...|                       
  Fly   707 TGRICNECKPLYW---NLN-ISNTEGC-EICDCWTDGTISAL----------------------- 743

  Fly  1190 DESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCCYA 1254
             ::|.::|.:|                 ||..|        |:..||   :.|.||:.:.:.  |
  Fly   744 -DTCTSKSGQC-----------------PCKPH--------TQGRRC---QECRDGTFDLDS--A 777

  Fly  1255 NQFRCNNGDC-VSGS--APC---NGYSECSDHSDELNCGG--TQECLPN----QFRCNSGQCVSS 1307
            :.|.|.:..| |.||  :.|   :|..:|......|.|..  |....|.    |:....|...|.
  Fly   778 SLFGCKDCSCDVGGSWQSVCDKISGQCKCHPRITGLACTQPLTTHFFPTLHQFQYEYEDGSLPSG 842

  Fly  1308 SVRCNGRTDCQDSSDEQNCA-------------ADSNDRRPNQLNLKTYPDSQIIKES-REVIFR 1358
            :         |...|....|             |..||.| |::|        :.|.| ..::.|
  Fly   843 T---------QVRYDYDEAAFPGFSSKGYVVFNAIQNDVR-NEVN--------VFKSSLYRIVLR 889

  Fly  1359 CRDEGPARAKVKWSRPGGRPL--------------PPGFTDRNGRLEI-PNIRVEDAGTYVCEA- 1407
            ..:..........|.....||              .|.|....|.|.: |:..|.|.|.||... 
  Fly   890 YVNPNAENVTATISVTSDNPLEVDQHVKVLLQPTSEPQFVTVAGPLGVKPSAIVLDPGRYVFTTK 954

  Fly  1408 ------VGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSD 1466
                  :.|...:|                       ...|:|..:....        .||    
  Fly   955 ANKNVMLDYFVLLP-----------------------AAYYEAGILTRHI--------SNP---- 984

  Fly  1467 ASDEQSCSLGLKCQPNQFMCSNSKCVD-------RTWRCDGENDCGDNSDETSCDPEPSGAPCRY 1524
                  |.||     |..:|.:.|...       .|....|||....|..||..|||........
  Fly   985 ------CELG-----NMELCRHYKYASVEVFSPAATPFVIGENSKPTNPVETYTDPEHLQIVSHV 1038

  Fly  1525 NEFQCRSG-----HCI---PKS----FQCD-----NVPDCTDGTDEVGCMAPLPIRPPPQS-VSL 1571
            .:....||     |.|   |:|    |..|     |.||        .....|.::..|.| .|:
  Fly  1039 GDIPVLSGSQNELHYIVDVPRSGRYIFVIDYISDRNFPD--------SYYINLKLKDNPDSETSV 1095

  Fly  1572 LEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTR 1636
            |.|..|..|...|...             .|..|...|     :...|::|.   ..|.:|.:  
  Fly  1096 LLYPCLYSTICRTSVN-------------EDGMEKSFY-----INKEDLQPV---IISADIED-- 1137

  Fly  1637 GTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECV----QCFCFGVAKACDSANLFTYAIH-- 1695
            |:.|    .|::|..:..|.....:.|    .:..||    ||.........||..:.....|  
  Fly  1138 GSRF----PIISVTAIPVDQWSIDYIN----PSPVCVIHDQQCATPKFRSVPDSKKIEFETDHED 1194

  Fly  1696 ------PPI--LSHRVVSVELSPLRQ--IVINEA--APGQDLLTLLHGVQFRATNVHFSGRETP- 1747
                  ||.  |..||..|.|....:  |||...  |...:|..:|         |.:.....| 
  Fly  1195 RIATNKPPYASLDERVKLVHLDSQNEATIVIESKVDATKPNLFVIL---------VKYYQPSHPK 1250

  Fly  1748 ---YLALPADYMGNQLKSYGGNLRYEVNY-------RGSGRPV-NGPDVIITGNRFTLTYRVRTQ 1801
               |..|.|.  .||   |.|  ::::.:       ||..||. .|...|....:||:|    |.
  Fly  1251 YQVYYTLTAG--KNQ---YDG--KFDIQHCPSSSGCRGVIRPAGEGSFEIDDEFKFTIT----TD 1304

  Fly  1802 PGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREV-----DLINIAL 1861
            ..|:  |.:.::                :::.|...::.|:.....|.|...:     |..:|..
  Fly  1305 RSQS--VWLDYL----------------VVVPLKQYNDDLLVEETFDQTKEFIQNCGHDHFHITH 1351

  Fly  1862 DSAGTADKGL-------------------GSASLV-----EKCQCPPGYVGDSCESCASGYVRQP 1902
            :::....|.:                   ||.|..     .:|||.|..:..:|.:|.|.|...|
  Fly  1352 NASDFCKKSVFSLTADYNSGALPCNCDYAGSTSFECHPFGGQCQCKPNVIERTCGACRSRYYGFP 1416

  Fly  1903 G------------GPWLGHC------VPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGC 1949
            .            .|..|.|      :..:.:.|...|||. .:.:.|:||.|...|..|..|.|
  Fly  1417 DCKPCKCPNSAMCEPTTGECMCPPNVIGDLCEKCAPNTYGF-HQVIGCEECACNPMGIANGNSQC 1480

  Fly  1950 QQSPDGDV---VCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGT---YSVHSNG 2008
                  |:   .|.|.:...||.|:.|:.||...|        .....||:..||   .....:|
  Fly  1481 ------DLFNGTCECRQNIEGRACDVCSNGYFNFP--------HCEQCSCHKPGTELEVCDKIDG 1531

  Fly  2009 TCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHG 2073
            .|.||.:|:|..||.|...:::|......||..|||.|....|||:      ....:..|.:.| 
  Fly  1532 ACFCKKNVVGRDCDQCVDGTYNLQESNPDGCTTCFCFGKTSRCDSA------YLRVYNVSLLKH- 1589

  Fly  2074 FVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPA-------------------- 2118
             |.:|     ||:....|:..:                 .|.:||                    
  Fly  1590 -VSIT-----TPEFHEESIKFD-----------------MWPVPADEILLNETTLKADFTLREVN 1631

  Fly  2119 ----AFLG---------NKLSSYGGKLTYTLSYSPLPNGIMSRN-SAPDVVIKSGEDLRLIHYRK 2169
                |:.|         |.:|:|||.|.|||.::   :|...:. .||||::.| |...|:|...
  Fly  1632 DERPAYFGVLDYLLNQNNHISAYGGDLAYTLHFT---SGFDGKYIVAPDVILFS-EHNALVHTSY 1692

  Fly  2170 SQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDV 2234
            .|...:...|..|.|.||.:|.......:|...:|.|.|:..|:|:|.|...|....|..|.|.:
  Fly  1693 EQPSRNEPFTNRVNIVESNFQTISGKPVSRADFMMVLRDLKVIFIRANYWEQTLVTHLSDVYLTL 1757

  Fly  2235 ATPTNLGTP--RAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSD 2297
            |.....||.  :.:.||:|.||.||.|.|||.|||||.|||.|. |.|.|.||||||||:.|:..
  Fly  1758 ADEDADGTGEYQFLAVERCSCPPGYSGHSCEDCAPGYYRDPSGP-YGGYCIPCECNGHSETCDCA 1821

  Fly  2298 TGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGI 2362
            ||.|.:|...|||..||||.:||.|:||.||..||.      |.:.|.|.:.....|: |:|.. 
  Fly  1822 TGICSKCQHGTEGDHCERCVSGYYGNATNGTPGDCM------ICACPLPFDSNNFATS-CEISE- 1878

  Fly  2363 YDCRGNE--CLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDF 2425
               .|::  |.||....|.:|:.|..|.||........||.|.|||                   
  Fly  1879 ---SGDQIHCECKPGYTGPRCESCANGFYGEPESIGQVCKPCECSG------------------- 1921

  Fly  2426 ILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLG--NQLFSYGGRLSYSL 2488
                              |:.|:...:..|.|            |..|.  |..|.....|.   
  Fly  1922 ------------------NINPEDQGSCDTRT------------GECLRCLNNTFGAACNLC--- 1953

  Fly  2489 IVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMT 2553
               :.|.|         |:.:||                             ::.:.....|..|
  Fly  1954 ---APGFY---------GDAIKL-----------------------------KNCQSCDCDDLGT 1977

  Fly  2554 VLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPL 2618
            ...|                                      ..:.:|.|....:|..|:.|.|.
  Fly  1978 QTCD--------------------------------------PFVGVCTCHENVIGDRCDRCKPD 2004

  Fly  2619 HYRDASG-SCSLCPCD-VSNTESCDLVSGGYVECRCKARWKG---DRCR------EIDTNDPTDI 2672
            ||...|| .|..|.|. .||:..||..:|   .|.||:...|   |||.      |.|...|.:.
  Fly  2005 HYGFESGVGCRACDCGAASNSTQCDPHTG---HCACKSGVTGRQCDRCAVDHWKYEKDGCTPCNC 2066

  Fly  2673 GTEDPVLTQIIVSIQKPEITIVPVGGSMTLSC---SGRM----------------RWSNSPVIVN 2718
            ..                      |.|....|   :|:.                ||        
  Fly  2067 NQ----------------------GYSRGFGCNPNTGKCQCLPGVIGDRCDACPNRW-------- 2101

  Fly  2719 WYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNN--------------ETASVFKDTVSI 2769
                                   :.:.|.|   ||..||              :..||.:|..|:
  Fly  2102 -----------------------VLIKDEG---CQECNNCHHALLDVTDRMRYQIDSVLEDFNSV 2140

  Fly  2770 TITRYAQEMLARYEK--DQLSPAEIVNLPSHVTF--EEYVNNEIICEVLGNPAPRV--TWARVDG 2828
            |:..:..:.|..|::  |:|.|...:..|:.|..  .:..|:|:..:. .:.|.:|  |.|....
  Fly  2141 TLAFFTSQKLNYYDQLADELEPKVKLLDPNSVDLSPSKKANSELESDA-KSYAKQVNQTLANAFD 2204

  Fly  2829 HADAQSTRTYDNRLIFDSPRKS-DEGRYRCQAENDQNRD---------------EKYVIVYVQSN 2877
            ..:..||...:..:.:|...|| |:.:....:....:::               .::::..:...
  Fly  2205 IRERSSTTLGNITVAYDEAVKSADQAKEAIASVEALSKNLEAAASTKIDAALEQAQHILGQINGT 2269

  Fly  2878 PPQPPPQQD------RLYITPEEINGLA----GESFQLNC------QFTSVASLRYDWSHNGRSL 2926
            ..:..|.:.      :||   ||:|.|.    .::..||.      :|:......::||...::.
  Fly  2270 SIELTPNEQVLEKARKLY---EEVNTLVLPIKAQNKSLNALKNDIGEFSDHLEDLFNWSEASQAK 2331

  Fly  2927 SSSPAR--------------------------NVEIRGNTLEVRDAS------ESDSGVYTCVAY 2959
            |:...|                          |::..||.|...|.:      :.|         
  Fly  2332 SADVERRNVANQKAFDNSKFDTVSEQKLQAEKNIKDAGNFLINGDLTLNQINQKLD--------- 2387

  Fly  2960 DVRTRRNFTESARVNIDR----REEQPFGNKPIIESLEQNI--LIIQGEDYSIT-CEASGSPYPS 3017
            ::|...|...|...|:|.    ||:|......:.:..||..  |.|:.:|.:.. .:.:.|..|:
  Fly  2388 NLRDALNELNSFNKNVDEELPVREDQHKEADALTDQAEQKAAELAIKAQDLAAQYTDMTASAEPA 2452

  Fly  3018 IKWAKVHDFMPENVH----ISGNVLTIYG-ARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPS 3077
            ||.|..:..:.|.|.    :|.:.::..| |..:..|    :.|..|.:|..||  |:..|.|.|
  Fly  2453 IKAATAYSGIVEAVEAAQKLSQDAISAAGNATDKTDG----IEERAHLADTGST--DLLQRARQS 2511

  Fly  3078 VKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGD 3142
            ::.|...|:. .:.|.|.....:..:.:.|             .|:::... .:||.:..|...|
  Fly  2512 LQKVQDDLEP-RLNASAGKVQKISAVNNAT-------------EHQLKDIN-KLIDQLPAESQRD 2561

  Fly  3143 YECRAKNIVGEATGVA--TITVQEPTLVQIIPD-------NRDLRLTEGDELSLTCVGSGVPNPE 3198
            ....:.....:|..:.  .:.:.||..||...:       ||||.||..|   ::.....:.:.|
  Fly  2562 MWKNSNANASDALEILKNVLEILEPVSVQTPKELEKAHGINRDLDLTNKD---VSQANKQLDDVE 2623

  Fly  3199 --VEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIG 3261
              |..::|:|  .|:...                        ::..||....:..|::..:..:.
  Fly  2624 GSVSKLSELA--EDIEEQ------------------------QHRVGSQSRQLGQEIENLKAQVE 2662

  Fly  3262 GVDD--DSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAP-- 3322
            ....  :|.:..:|:.|.....  :..|...:||||...            |:|.:...:.:.  
  Fly  2663 AARQLANSIKVGVNFKPSTILE--LKTPEKTKLLATRTN------------LSTYFRTTEPSGFL 2713

  Fly  3323 --LPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVE 3385
              |..:..|.:...:.|.||       ..||                         ||  .||::
  Fly  2714 LYLGNDNKTAQKNNDFVAVE-------IVNG-------------------------YP--ILTID 2744

  Fly  3386 AGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRS 3450
            .|..           ||                       |..|....|.|.:..:..::.|.. 
  Fly  2745 LGNG-----------PE-----------------------RITSDKYVADGRWYQAVVDRMGPN- 2774

  Fly  3451 QIARVAVKKPADFHQVPQSQLQRHR-----EGENIQLQCTVTDQYGVRAQDNV-EFNWFRDDRRP 3509
              |::.:::     ::|...:..|.     ||....|......:..|.....: :||        
  Fly  2775 --AKLTIRE-----ELPNGDVVEHSKSGYLEGSQNILHVDKNSRLFVGGYPGISDFN-------- 2824

  Fly  3510 LPNNARTDSQILVLTNLRPEDAGRYICN---SYDVDRGQQLPEVSIDLQVLRAPQYPYN--RFKG 3569
            .|.:..|:|....:.:|:..|....:.|   ..|.|:|.:      :..||...:.|..  ||||
  Fly  2825 APPDLTTNSFSGDIEDLKIGDESVGLWNFVYGDDNDQGAR------ERDVLLEKKKPVTGLRFKG 2883

  Fly  3570 GVSLKDTPCMVLYICAAATPPPNSPIYLPPQLPAKSR---DYSLKLDDQSSNLRAGESTDVECYS 3631
                                  |..:.|......|||   .:|.|.|..:||      ..:..|.
  Fly  2884 ----------------------NGYVQLNATSNLKSRSSIQFSFKADKDTSN------GLLFFYG 2920

  Fly  3632 SDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTS--YKLEVE 3694
            .|..|..:  |..|||             :..|:|..:.|.    .::...|.|..:  :|::.|
  Fly  2921 RDKHYMSI--EMIDGA-------------IFFNISLGEGGG----VQSGSQDRYNDNQWHKVQAE 2966

  Fly  3695 DQPHE--LKSSKIVYAKVGA--NADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSL----- 3750
            .:...  ||...||.::..|  .|||:.       |..|  |.|......|  :|..:||     
  Fly  2967 RENRNGLLKVDDIVISRTNAPLEADLEL-------PKLR--RLYFGGHPRR--LNTSISLQPNFD 3020

  Fly  3751 ---DSVQAN----DAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKF 3808
               |:|..|    |...|:......:|.:|.|..::         ...|..| .|..:.|.|...
  Fly  3021 GCIDNVVINQGVVDLTEYVTGGGVEEGCSAKFSTVV---------SYAPHEY-GFLRMNNVSSDN 3075

  Fly  3809 NFE--LTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHT 3871
            |..  |.|:....:| :||..........|.|||:|...:.. ..|.:  ||..:..|...|.|.
  Fly  3076 NLHVVLHFKTTQPNG-VLFYAANHDQSSTIGLSLQDGLLKLN-SMGSQ--LVIDDRILNDGEDHV 3136

  Fly  3872 VRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIE--DLYIGGVPNWELLPADAVSQQVGFVGCI 3934
            |.|...:.:..:.||:.......:    ||..::|  |::..|:|:....|.:|::....|||||
  Fly  3137 VTVQHTQGELRLTVDDVDNKRLGS----PQPLILEGGDIFFAGLPDNYRTPRNALASLAYFVGCI 3197

  Fly  3935 SRLTLQGRTVELIREAKYKEG-ITDCRP--CAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCA 3996
            |.:|:....:.....|:.|.| |..|.|  .|..|............|      .:..|:..|..
  Fly  3198 SDVTVNEEIINFANSAEKKNGNINGCPPHVLAYEPSLVPSYYPSGDNE------VESPWSNADTL 3256

  Fly  3997 ------IEGT--QCTPGVCGAGRCENT---------------------ENDMECLCP-------- 4024
                  ||.|  ..||..........|                     |.::|...|        
  Fly  3257 PPLKPDIESTLPPTTPTTTTTTTTTTTSTTTTSTTTTTTTPSPIVIDEEKEIEAKTPQKILTTRP 3321

  Fly  4025 ---LN-RSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTL 4085
               || .|.:||:..|..| ..::|....:..||..:......:|.|:.....|..|.:..|.  
  Fly  3322 PAKLNLPSDERCKLPEQPN-FDVDFTEAGYRFYGLREQRLQINSLPVKVRRHHDIGISFRTER-- 3383

  Fly  4086 PSG-----------DYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLN--RWTRIEIRRRLGE 4137
            |:|           |::|:.|..|.....|...|:|...:...||   ||  .|..:|:.|...:
  Fly  3384 PNGLLIYAGSKQRDDFIAVYLLDGRVTYEIRVGAQLQAKITTEAE---LNDGTWHTVEVVRTQRK 3445

  Fly  4138 GILRVGDGPERKAKAPGS-----DR---ILSLKTHLYVGGYDR---STVKVNRDVNIT------K 4185
            ..|.:.     |.:.|||     :|   :|:::..:|:||.::   |.||     |:|      .
  Fly  3446 VSLLID-----KLEQPGSVDLNAERSAPVLAVELPIYLGGVNKFLESEVK-----NLTDFKTEVP 3500

  Fly  4186 GFDGCISRLYNFQKPVNLLADIK-DAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPY 4249
            .|:||             |.:|| ||.::::                    ||         :.:
  Fly  3501 YFNGC-------------LKNIKFDAMDLET--------------------PP---------EEF 3523

  Fly  4250 AMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPAL 4314
            .:.|| |:..|.|                            |.||   ....:|:: ..||....
  Fly  3524 GVVPC-SEQVERG----------------------------LFFN---NQKAFVKI-FDHFDVGT 3555

  Fly  4315 EQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAV-----IR 4374
            |.   .:...|....||||||       ..:....:....:||..:.::::.|.:..|     :.
  Fly  3556 EM---KISFDFRPRDPNGLLF-------SVHGKNSYAILELVDNTLYFTVKTDLKNIVSTNYKLP 3610

  Fly  4375 NSDIRVDNGERHIVIAKR------------------DENTAILEVDRMLHSGETRPTSKKSMKLP 4421
            |::...|...|::...|.                  :|.:.|...:|.|                
  Fly  3611 NNESFCDGKTRNVQAIKSKFVINIAVDFISSNPGVGNEGSVITRTNRPL---------------- 3659

  Fly  4422 GNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQ--INLS-SAAVNGVNANVCPAN 4477
               |:||....:...|.:.|.:..|||..||   |.|  ||:: :..|..:....||.|
  Fly  3660 ---FLGGHVAFQRAPGIKTKKSFKGCISKVE---VNQRMINITPNMVVGDIWQGYCPLN 3712

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
trolNP_001401049.1 LDLa 447..480 CDD:238060
LDLa 532..564 CDD:238060
LDLa 571..606 CDD:238060 11/32 (34%)
LDLa 616..650 CDD:238060 12/45 (27%)
LDLa 704..739 CDD:238060 10/42 (24%)
LDLa 813..847 CDD:238060 6/40 (15%)
LDLa 852..887 CDD:238060 6/35 (17%)
LDLa 902..936 CDD:238060 11/45 (24%)
LDLa 956..990 CDD:238060 9/39 (23%)
LDLa 997..1030 CDD:238060 10/39 (26%)
LDLa 1033..1067 CDD:238060 7/34 (21%)
LDLa 1072..1105 CDD:238060 10/40 (25%)
LDLa 1133..1165 CDD:238060 13/32 (41%)
LDLa 1182..1215 CDD:238060 3/32 (9%)
LDLa 1221..1251 CDD:238060 7/29 (24%)
LDLa 1252..1286 CDD:238060 11/39 (28%)
LDLa 1292..1326 CDD:238060 6/37 (16%)
Ig 1344..1405 CDD:472250 15/76 (20%)
Ig strand B 1355..1359 CDD:409353 0/3 (0%)
Ig strand C 1369..1372 CDD:409353 0/2 (0%)
Ig strand E 1388..1392 CDD:409353 2/3 (67%)
LDLa 1439..1473 CDD:238060 4/33 (12%)
LDLa 1479..1513 CDD:238060 10/40 (25%)
LDLa 1522..1556 CDD:238060 11/50 (22%)
Ig_Perlecan_like 1574..1649 CDD:143220 14/74 (19%)
Ig strand B 1577..1583 CDD:143220 2/5 (40%)
Ig strand C 1590..1595 CDD:143220 0/4 (0%)
Ig strand E 1613..1617 CDD:143220 0/3 (0%)
Ig strand F 1626..1632 CDD:143220 1/5 (20%)
Ig strand G 1641..1647 CDD:143220 0/5 (0%)
Laminin_B 1748..1878 CDD:459652 29/166 (17%)
EGF_Lam 1935..1989 CDD:238012 16/56 (29%)
Laminin_B 2113..2249 CDD:459652 45/171 (26%)
EGF_Lam <2250..2276 CDD:238012 17/25 (68%)
EGF_Lam 2284..2333 CDD:238012 28/48 (58%)
Laminin_EGF <2369..2399 CDD:395007 9/31 (29%)
Laminin_B 2465..2599 CDD:459652 13/135 (10%)
Ig_3 2688..2756 CDD:464046 10/86 (12%)
Ig_3 2791..2861 CDD:464046 14/74 (19%)
Ig_3 2890..2958 CDD:464046 17/109 (16%)
Ig 2987..3071 CDD:472250 22/91 (24%)
Ig strand B 3004..3008 CDD:409353 0/4 (0%)
Ig strand C 3017..3021 CDD:409353 2/3 (67%)
Ig strand E 3036..3040 CDD:409353 0/3 (0%)
Ig strand F 3050..3055 CDD:409353 0/4 (0%)
Ig strand G 3063..3066 CDD:409353 0/2 (0%)
I-set 3089..3162 CDD:400151 9/74 (12%)
Ig strand B 3094..3098 CDD:409353 1/3 (33%)
Ig strand C 3107..3111 CDD:409353 1/3 (33%)
Ig strand E 3128..3132 CDD:409353 0/3 (0%)
Ig strand F 3142..3147 CDD:409353 1/4 (25%)
Ig strand G 3155..3158 CDD:409353 0/2 (0%)
Ig 3165..3253 CDD:472250 17/96 (18%)
Ig strand B 3185..3189 CDD:409353 0/3 (0%)
Ig strand C 3198..3202 CDD:409353 2/5 (40%)
Ig strand E 3219..3223 CDD:409353 0/3 (0%)
Ig strand F 3233..3238 CDD:409353 0/4 (0%)
Ig strand G 3246..3249 CDD:409353 0/2 (0%)
Ig 3298..3355 CDD:472250 9/60 (15%)
Ig strand B 3301..3305 CDD:409353 0/3 (0%)
Ig strand C 3313..3316 CDD:409353 1/2 (50%)
Ig strand E 3333..3336 CDD:409353 0/2 (0%)
IG_like 3381..3457 CDD:214653 11/75 (15%)
Ig strand B 3390..3394 CDD:409353 0/3 (0%)
Ig strand C 3403..3407 CDD:409353 0/3 (0%)
Ig strand F 3437..3442 CDD:409353 0/4 (0%)
IG_like 3475..>3536 CDD:214653 11/66 (17%)
Ig strand B 3480..3484 CDD:409353 1/3 (33%)
Ig strand C 3491..3503 CDD:409353 3/12 (25%)
Ig strand E 3519..3523 CDD:409353 0/3 (0%)
Ig 3613..3675 CDD:472250 13/61 (21%)
Ig strand B 3625..3629 CDD:409353 0/3 (0%)
Ig strand C 3637..3642 CDD:409353 0/4 (0%)
Ig strand E 3658..3662 CDD:409353 0/3 (0%)
IG_like 3706..3772 CDD:214653 19/79 (24%)
Ig strand B 3714..3718 CDD:409353 3/3 (100%)
Ig strand C 3727..3731 CDD:409353 1/3 (33%)
Ig strand E 3746..3750 CDD:409353 0/3 (0%)
Ig strand F 3760..3765 CDD:409353 1/4 (25%)
Ig strand G 3774..3777 CDD:409353 1/2 (50%)
LamG 3794..3939 CDD:238058 39/148 (26%)
EGF 3962..3994 CDD:394967 4/31 (13%)
LamG 4042..4195 CDD:238058 42/182 (23%)
EGF_CA 4254..4286 CDD:238011 4/31 (13%)
LamG 4295..4448 CDD:238058 29/175 (17%)
LanANP_476617.1 LamNT 18..271 CDD:214532 2/8 (25%)
EGF_Lam 272..>314 CDD:238012 16/50 (32%)
EGF_Lam 332..389 CDD:238012 13/79 (16%)
EGF_Lam 402..443 CDD:238012 13/127 (10%)
Laminin_EGF 448..497 CDD:395007 15/87 (17%)
Laminin_EGF 495..543 CDD:395007 13/75 (17%)
Laminin_EGF 541..589 CDD:395007 15/58 (26%)
Laminin_EGF 587..634 CDD:395007 15/59 (25%)
Laminin_EGF 632..679 CDD:395007 11/48 (23%)
Laminin_EGF 677..729 CDD:395007 11/55 (20%)
Laminin_EGF 732..782 CDD:395007 19/103 (18%)
EGF_Lam 785..828 CDD:238012 11/42 (26%)
CBM6-CBM35-CBM36_like 831..966 CDD:271143 29/152 (19%)
Laminin_EGF 1375..1423 CDD:395007 12/47 (26%)
EGF_Lam 1420..1457 CDD:238012 6/36 (17%)
Laminin_EGF 1466..1516 CDD:395007 16/63 (25%)
Laminin_EGF 1514..1562 CDD:395007 14/47 (30%)
LamB 1632..1760 CDD:214597 40/131 (31%)
Laminin_EGF <1775..1801 CDD:395007 17/25 (68%)
EGF_Lam 1808..1851 CDD:238012 25/42 (60%)
EGF_Lam 1859..1907 CDD:214543 15/52 (29%)
EGF_Lam 1916..1968 CDD:238012 18/144 (13%)
EGF_Lam 1969..2015 CDD:238012 13/83 (16%)
EGF_Lam 2016..>2054 CDD:238012 14/40 (35%)
EGF_Lam 2063..>2097 CDD:238012 5/55 (9%)
Laminin_I 2134..2385 CDD:310534 41/254 (16%)
SMC_prok_B 2356..>2705 CDD:274008 79/421 (19%)
Laminin_II 2566..2700 CDD:368703 28/176 (16%)
LamG 2674..2843 CDD:238058 41/266 (15%)
LamG 2878..3029 CDD:238058 46/208 (22%)
LamG 3078..3205 CDD:214598 35/134 (26%)
LamG 3349..3512 CDD:238058 44/190 (23%)
LamG 3535..3689 CDD:238058 37/217 (17%)
Blue background indicates that the domain is not in the aligned region.

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