Protein Alignment trol and CG6739

DIOPT Version :10

• Sequence 1: NP_001401049.1
• Gene: trol / 45320
• FlyBaseID: FBgn0284408
• Length: 4489
• Species: Drosophila melanogaster
• Sequence 2: NP_609130.1
• Gene: CG6739 / 34037
• FlyBaseID: FBgn0031926
• Length: 787
• Species: Drosophila melanogaster
• Alignment Length: 406
• Identity: 98/406 - (24%)
• Similarity: 162/406 - (39%)
• Gaps: 98/406 - (24%)

  Fly   514 PESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPAACSGMEYQC 578
            |::....:.|......:.|..|||:|::|.||....:|:.:.||..||||:|:| ..|...|::|
  Fly   414 PDAHESHKCEDPTRRRDYCYGNEFQCHDGSCIPQNWQCDKIKDCQGGEDEDEQC-LVCEPDEFRC 477

  Fly   579 RDGTRCISVSQQCDGHSDCSDGDDEEHCD--GSGYDSEECRFDEFHCGTGECIPMRQVCDNIYDC 641
            |...:|:....:||.:.||.||.||:.||  |||   :...|||...   ...|......:....
  Fly   478 RSNEKCLVEKYRCDQNIDCMDGSDEQDCDEYGSG---DLAPFDESEL---NAFPRVFTYASFLSP 536

  Fly   642 NDYSDEV-NCVEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQ------PSNVYEKAN 699
            |:.:|:| ..:....::..|                     ..:::|::|      |.|...:..
  Fly   537 NETNDKVYTYITATTDEDAG---------------------TETKFQIHQVAAPAPPVNSSAEEG 580

  Fly   700 SQNPCASNQFRCTTSNVCIPLHLRCDGFYHCND------MSDEKSCEQY-QRHTTTRRPLTLA-- 755
            :..|                     .||.:..|      .||.::..:| ||...|....:::
  Fly   581 AGGP---------------------KGFVNFRDSKEIMMTSDSETKFKYSQRANRTSVKFSVSAP 624

  Fly   756 -TPTSRITTQGP--GLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVANSPPQTCLENI 817
             ||.:|.::..|  .|:::|..||:|       .|.:||.:||||:..:|..:.:    |.|..|
  Fly   625 TTPAARTSSAIPSSALVQQRERTTST-------TTTSTTTSTTTSSITSTPSITS----TTLIPI 678

  Fly   818 EFACHNRDCISIESVCDGIPDCGRNEDEDDALCKCSGDKYKCQRGGGCIPKSQVCDGKPQCHDRS 882
            ..|....:...:.:...|                |...:.:|. .|.||..||:||.:..|.|.:
  Fly   679 NAATSEPNPYEVVTSLGG----------------CPPQELRCV-SGKCITVSQLCDKQIDCPDAA 726

  Fly   883 DESACHLHGRLNKTRL 898
            ||..|....|.::.||
  Fly   727 DELMCVYRERPSRRRL 742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trol	NP_001401049.1	LDLa	447..480	CDD:238060
		LDLa	532..564	CDD:238060	14/31 (45%)
		LDLa	571..606	CDD:238060	13/34 (38%)
		LDLa	616..650	CDD:238060	7/34 (21%)
		LDLa	704..739	CDD:238060	5/40 (13%)
		LDLa	813..847	CDD:238060	4/33 (12%)
		LDLa	852..887	CDD:238060	13/34 (38%)
		LDLa	902..936	CDD:238060
		LDLa	956..990	CDD:238060
		LDLa	997..1030	CDD:238060
		LDLa	1033..1067	CDD:238060
		LDLa	1072..1105	CDD:238060
		LDLa	1133..1165	CDD:238060
		LDLa	1182..1215	CDD:238060
		LDLa	1221..1251	CDD:238060
		LDLa	1252..1286	CDD:238060
		LDLa	1292..1326	CDD:238060
		Ig	1344..1405	CDD:472250
		Ig strand B	1355..1359	CDD:409353
		Ig strand C	1369..1372	CDD:409353
		Ig strand E	1388..1392	CDD:409353
		LDLa	1439..1473	CDD:238060
		LDLa	1479..1513	CDD:238060
		LDLa	1522..1556	CDD:238060
		Ig_Perlecan_like	1574..1649	CDD:143220
		Ig strand B	1577..1583	CDD:143220
		Ig strand C	1590..1595	CDD:143220
		Ig strand E	1613..1617	CDD:143220
		Ig strand F	1626..1632	CDD:143220
		Ig strand G	1641..1647	CDD:143220
		Laminin_B	1748..1878	CDD:459652
		EGF_Lam	1935..1989	CDD:238012
		Laminin_B	2113..2249	CDD:459652
		EGF_Lam	<2250..2276	CDD:238012
		EGF_Lam	2284..2333	CDD:238012
		Laminin_EGF	<2369..2399	CDD:395007
		Laminin_B	2465..2599	CDD:459652
		Ig_3	2688..2756	CDD:464046
		Ig_3	2791..2861	CDD:464046
		Ig_3	2890..2958	CDD:464046
		Ig	2987..3071	CDD:472250
		Ig strand B	3004..3008	CDD:409353
		Ig strand C	3017..3021	CDD:409353
		Ig strand E	3036..3040	CDD:409353
		Ig strand F	3050..3055	CDD:409353
		Ig strand G	3063..3066	CDD:409353
		I-set	3089..3162	CDD:400151
		Ig strand B	3094..3098	CDD:409353
		Ig strand C	3107..3111	CDD:409353
		Ig strand E	3128..3132	CDD:409353
		Ig strand F	3142..3147	CDD:409353
		Ig strand G	3155..3158	CDD:409353
		Ig	3165..3253	CDD:472250
		Ig strand B	3185..3189	CDD:409353
		Ig strand C	3198..3202	CDD:409353
		Ig strand E	3219..3223	CDD:409353
		Ig strand F	3233..3238	CDD:409353
		Ig strand G	3246..3249	CDD:409353
		Ig	3298..3355	CDD:472250
		Ig strand B	3301..3305	CDD:409353
		Ig strand C	3313..3316	CDD:409353
		Ig strand E	3333..3336	CDD:409353
		IG_like	3381..3457	CDD:214653
		Ig strand B	3390..3394	CDD:409353
Ig strand C	3403..3407	CDD:409353
Ig strand F	3437..3442	CDD:409353
IG_like	3475..>3536	CDD:214653
Ig strand B	3480..3484	CDD:409353
Ig strand C	3491..3503	CDD:409353
Ig strand E	3519..3523	CDD:409353
Ig	3613..3675	CDD:472250
Ig strand B	3625..3629	CDD:409353
Ig strand C	3637..3642	CDD:409353
Ig strand E	3658..3662	CDD:409353
IG_like	3706..3772	CDD:214653
Ig strand B	3714..3718	CDD:409353
Ig strand C	3727..3731	CDD:409353
Ig strand E	3746..3750	CDD:409353
Ig strand F	3760..3765	CDD:409353
Ig strand G	3774..3777	CDD:409353
LamG	3794..3939	CDD:238058
EGF	3962..3994	CDD:394967
LamG	4042..4195	CDD:238058
EGF_CA	4254..4286	CDD:238011
LamG	4295..4448	CDD:238058
CG6739	NP_609130.1	CRD_FZ	314..427	CDD:143549	2/12 (17%)
		LDLa	432..464	CDD:238060	14/31 (45%)
		LDLa	470..505	CDD:238060	13/34 (38%)
		LDLa	697..731	CDD:238060	13/34 (38%)