Protein Alignment kn and Ebf4

DIOPT Version :10

• Sequence 1: NP_001097317.1
• Gene: kn / 45318
• FlyBaseID: FBgn0001319
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: XP_038961773.1
• Gene: Ebf4 / 680751
• RGDID: 1588215
• Length: 777
• Species: Rattus norvegicus
• Alignment Length: 692
• Identity: 373/692 - (53%)
• Similarity: 430/692 - (62%)
• Gaps: 164/692 - (23%)

  Fly   139 LYPSAVSGP-----RSAGG-----------------LMFGLPP----------TAAVDMNQ---- 167
            |.|.|.:||     |.:||                 |:..|||          |||...::
  Rat    41 LPPGAAAGPGRRGTRGSGGGCVCWPSAGPAFPRDARLLLLLPPRPPPSPPPTSTAAASPSRMDAL 105

  Fly   168 PRGPMTSLKEEP-----LGS--RWAMQP--VVD-----QSNLGIGRAHFEKQPPSNLRKSNFFHF 218
            |||.: .|||||     |||  .| ||.  ::|     ||.:|:.||||||||||||||||||||
  Rat   106 PRGGL-HLKEEPLLPSSLGSVRSW-MQSAGILDSSTAAQSGVGLARAHFEKQPPSNLRKSNFFHF 168

  Fly   219 VIALYDRAGQPIEIERTAFIGFIEKDSESDATKTNNGIQYRLQLLYANGARQEQDIFVRLIDSVT 283
            |:|:|||.|||:|:||||||.|:|||.|....||||||.|||:|:|.||.|.|||::||||||::
  Rat   169 VLAMYDRQGQPVEVERTAFIDFVEKDREPGTEKTNNGIHYRLRLVYNNGLRTEQDLYVRLIDSMS 233

  Fly   284 KQAIIYEGQDKNPEMCRVLLTHEVMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLK 348
            |||||||||||||||||||||||:|||||||:|||||||||||||||||||||||||||||||||
  Rat   234 KQAIIYEGQDKNPEMCRVLLTHEIMCSRCCDRKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLK 298

  Fly   349 NAGNPRDMRRFQVVISTQVAVDGPLLAISDNMFVHNNSKHGRRAKRLDTTEGTGNTSLSISGHP- 412
            ||||||||||||||:||.|:|||.:||:||||||||||||||||:|||.:|  |..|....|.|
  Rat   299 NAGNPRDMRRFQVVVSTTVSVDGHVLAVSDNMFVHNNSKHGRRARRLDPSE--GQDSQPSPGQPQ 361

  Fly   413 -LAPDSTYDGLYPPLPVATPCIKAISPSEGWTTGGATVIIVGDNFFDGLQVVFGTMLVWSELITS 476
             |...|....:...||.||||||||||.||||||||||||:|||||||||||||.:|:||||||.
  Rat   362 SLPWCSPLTWVLSYLPAATPCIKAISPGEGWTTGGATVIIIGDNFFDGLQVVFGNVLLWSELITP 426

  Fly   477 HAIRVQTPPRHIPGVVEVTLSYKSKQFCKGSPGRFVYVSALNEPTIDYGFQRLQKLIPRHPGDPE 541
            ||:|||||||||||||||||||||||||||:|||||| :||||||||||||||||:|||||||||
  Rat   427 HALRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFVY-TALNEPTIDYGFQRLQKVIPRHPGDPE 490

  Fly   542 KLQKEIILKRAADL----------------------VEALYSMPRSPG------------GSTGF 572
            :|.||::|||||||                      .|||||.||:|.            ...|.
  Rat   491 RLPKEVLLKRAADLAEALYGVPNSNQELLLKRAADVAEALYSAPRAPAPLGPLAPSHPHPAVVGI 555

  Fly   573 NSYAGQLAVSVQDGSGQWTEDDYQRAQSSSVSPR-----GGYCSSASTPHSSG-GSYGA------ 625
            |:::..||::|.|.:   .|..|.|: ..|.|||     |...||..:...:| |||||
  Rat   556 NAFSSPLAIAVGDAT---PEPGYARS-CGSASPRFAPSPGSQQSSYGSGLGAGLGSYGAPGVTGL 616

  Fly   626 ------------TAA------------------------------------SAAVAATANGYAPA 642
                        ||.                                    |..|:.||...|||
  Rat   617 GVPGSPSFLNGSTATSPFASPHIPGRPEPAAWSTGTHCPRDTPTLLLTLVLSPVVSPTAFPAAPA 681

  Fly   643 PNM---GTLSSSPGSVFNSTSRVSSLSFNPFALPTCNTQGYS 681
            |:.   |.:.|||     ..:..||:|. |.|.||.:...:|
  Rat   682 PSSPRPGVMPSSP-----PLAAASSMSL-PAAAPTTSVFSFS 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kn	NP_001097317.1	COE_DBD	184..395	CDD:212156	171/217 (79%)
		IPT_COE	431..515	CDD:238580	75/83 (90%)
		COE1_HLH	517..560	CDD:406751	36/64 (56%)
Ebf4	XP_038961773.1	COE1_DBD	119..345	CDD:435333	174/226 (77%)
		IPT_COE	381..465	CDD:238580	75/84 (89%)
		COE1_HLH	466..509	CDD:406751	34/42 (81%)