Protein Alignment kn and ebf3a

DIOPT Version :9

• Sequence 1: NP_001097317.1
• Gene: kn / 45318
• FlyBaseID: FBgn0001319
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: XP_009305176.1
• Gene: ebf3a / 567751
• ZFINID: ZDB-GENE-070112-292
• Length: 597
• Species: Danio rerio
• Alignment Length: 584
• Identity: 366/584 - (62%)
• Similarity: 414/584 - (70%)
• Gaps: 96/584 - (16%)

  Fly   154 MFGLPPTAAVDMNQPRGPMTSLKEEPLGSRWAMQP---------VVD-----QSNLGIGRAHFEK 204
            |||      :..|.|||. |::|||||||  .|.|         |||     ||.:|:.|||:||
Zfish     1 MFG------IQENIPRGG-TTMKEEPLGS--GMNPVRSWMHTAGVVDAHTAAQSGVGLARAHYEK 56

  Fly   205 QPPSNLRKSNFFHFVIALYDRAGQPIEIERTAFIGFIEKDSESDATKTNNGIQYRLQLLYANGAR 269
            |||||||||||||||:|||||.|||:|||||||:.|:||:.|.::.||||||.|:|||||:||.|
Zfish    57 QPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVDFVEKEKEPNSEKTNNGIHYKLQLLYSNGVR 121

  Fly   270 QEQDIFVRLIDSVTKQAIIYEGQDKNPEMCRVLLTHEVMCSRCCDKKSCGNRNETPSDPVIIDRF 334
            .|||::||||||:||||||||||||||||||||||||:|||||||||||||||||||||||||||
Zfish   122 TEQDLYVRLIDSMTKQAIIYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRF 186

  Fly   335 FLKFFLKCNQNCLKNAGNPRDMRRFQVVISTQVAVDGPLLAISDNMFVHNNSKHGRRAKRLDTTE 399
            ||||||||||||||||||||||||||||:||.|.|||.:||:||||||||||||||||:|||.:|
Zfish   187 FLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSE 251

  Fly   400 GTGNTSLSISGHPLAPDSTYDGLYPPLPVATPCIKAISPSEGWTTGGATVIIVGDNFFDGLQVVF 464
            ||....|.                   ..|||||||||||||||||||||||:||||||||||||
Zfish   252 GTATPYLE-------------------NAATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVVF 297

  Fly   465 GTMLVWSELITSHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGSPGRFVYVSALNEPTIDYGFQRL 529
            |||||||||||.||||||||||||||||||||||||||||||:|||||| :||||||||||||||
Zfish   298 GTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFVY-TALNEPTIDYGFQRL 361

  Fly   530 QKLIPRHPGDPEKLQKEIILKRAADLVEALYSMPR------------------------------ 564
            ||:|||||||||:|.||::||||||||||||.||.
Zfish   362 QKVIPRHPGDPERLPKEVLLKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQIPSL 426

  Fly   565 ----SPGGSTGFNSYAGQLAVSVQDGSGQWTEDDYQRAQSSSVSPRGGYCSSASTPHSSGGSYGA 625
                |.||..|.||::.||||:|.:.|    :..|.| .:|||||| ||..| |||..|  :|.
Zfish   427 ANTASHGGMMGVNSFSSQLAVNVSETS----QVGYSR-NTSSVSPR-GYVPS-STPQQS--NYN- 481

  Fly   626 TAASAAVAATANGYAPA--PNMGTLSSSPGSVFNSTSRVSSLSFNPFALPTCNTQGYSTQLVTS 687
                 .|:.:.|||...  ||:| :.|||| ..|.:|..|........:|:..|...|:..::|
Zfish   482 -----TVSNSMNGYGNTGMPNLG-VPSSPG-FLNGSSANSPYGSKYQVVPSSPTMAASSVSLSS 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kn	NP_001097317.1	COE_DBD	184..395	CDD:212156	174/224 (78%)
		IPT_COE	431..515	CDD:238580	80/83 (96%)
		COE1_HLH	517..560	CDD:293032	37/42 (88%)
ebf3a	XP_009305176.1	COE1_DBD	21..247	CDD:293031	176/227 (78%)
		IPT_COE	264..348	CDD:238580	80/84 (95%)
		COE1_HLH	349..392	CDD:293032	37/42 (88%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595169
Domainoid	1	1.000	374	1.000	Domainoid score	I834
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56472
Inparanoid	1	1.050	648	1.000	Inparanoid score	I781
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352969at33208
OrthoFinder	1	1.000	-	-		FOG0000764
OrthoInspector	1	1.000	-	-		otm25853
orthoMCL	1	0.900	-	-		OOG6_102533
Panther	1	1.100	-	-	O	PTHR10747
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2885
SonicParanoid	1	1.000	-	-		X577
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.930