Protein Alignment kn and ebf1a

DIOPT Version :10

• Sequence 1: NP_001097317.1
• Gene: kn / 45318
• FlyBaseID: FBgn0001319
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: XP_009289482.1
• Gene: ebf1a / 565310
• ZFINID: ZDB-GENE-081028-51
• Length: 606
• Species: Danio rerio
• Alignment Length: 582
• Identity: 368/582 - (63%)
• Similarity: 413/582 - (70%)
• Gaps: 101/582 - (17%)

  Fly   154 MFGLPPTAAVDMNQPRGPMTSLKEEPLGS-----RWAMQ--PVVD-----QSNLGIGRAHFEKQP 206
            |||:.     |..|..|  :|:||||:|:     |..||  .|:|     ||.:|:.||||||||
Zfish     1 MFGIQ-----DSIQRSG--SSMKEEPIGAGMNAVRTWMQGAGVLDANTAAQSGVGLARAHFEKQP 58

  Fly   207 PSNLRKSNFFHFVIALYDRAGQPIEIERTAFIGFIEKDSESDATKTNNGIQYRLQLLYANGARQE 271
            |||||||||||||:|||||.|||:|||||:|:||:||:.||...||||||.|||||||:||.|.|
Zfish    59 PSNLRKSNFFHFVLALYDRQGQPVEIERTSFVGFVEKEKESTGEKTNNGIHYRLQLLYSNGIRTE 123

  Fly   272 QDIFVRLIDSVTKQAIIYEGQDKNPEMCRVLLTHEVMCSRCCDKKSCGNRNETPSDPVIIDRFFL 336
            ||.:||||||:||||||||||||||||||||||||:|||||||||||||||||||||||||||||
Zfish   124 QDFYVRLIDSMTKQAIIYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFL 188

  Fly   337 KFFLKCNQNCLKNAGNPRDMRRFQVVISTQVAVDGPLLAISDNMFVHNNSKHGRRAKRLDTTEGT 401
            ||||||||||||||||||||||||||:||.|:|||.:||:||||||||||||||||:|||.:|||
Zfish   189 KFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVSVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGT 253

  Fly   402 GNTSLSISGHPLAPDSTYDGLYPPLPVATPCIKAISPSEGWTTGGATVIIVGDNFFDGLQVVFGT 466
                         |.....|      .:||||||||||||||||||||||:||||||||||:|||
Zfish   254 -------------PSYLEHG------ESTPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGT 299

  Fly   467 MLVWSELITSHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGSPGRFVYVSALNEPTIDYGFQRLQK 531
            |||||||||.||||||||||||||||||||||||||||||:||||:| :||||||||||||||||
Zfish   300 MLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIY-TALNEPTIDYGFQRLQK 363

  Fly   532 LIPRHPGDPEKLQKEIILKRAADLVEALYSMPRS--------------------------PG--- 567
            :|||||||||:|.||:|||||||||||||.||.:                          ||
Zfish   364 VIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYNVPRGHNQLPGLTN 428

  Fly   568 -----GSTGFNSYAGQLAVSVQDGSGQWTEDDYQRAQSSSVSPRGGYCSSASTPHSSGGSYGATA 627
                 |..|.||:..||||:|.| |.|.....:.| .:|||||. ||..| :||..|  ||
Zfish   429 SSVHSGMMGVNSFHSQLAVNVSD-STQAANQGFSR-NTSSVSPH-GYVPS-TTPQQS--SY---- 483

  Fly   628 ASAAVAATANGYAPAPNMGTLSSSP----GSVFNSTSRVSSLSFNPFAL-PTCNTQGYSTQL 684
              :.|:.:.|||..| .|.||..||    ||..||          |:|: |:..|...||.|
Zfish   484 --STVSTSMNGYGNA-GMTTLGGSPNFLNGSAANS----------PYAIVPSSPTMASSTSL 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kn	NP_001097317.1	COE_DBD	184..395	CDD:212156	176/217 (81%)
		IPT_COE	431..515	CDD:238580	78/83 (94%)
		COE1_HLH	517..560	CDD:406751	38/42 (90%)
ebf1a	XP_009289482.1	COE1_DBD	21..247	CDD:435333	178/225 (79%)
		IPT_COE	264..348	CDD:238580	78/84 (93%)
		COE1_HLH	349..392	CDD:406751	38/42 (90%)