Protein Alignment kn and Ebf4

DIOPT Version :9

• Sequence 1: NP_001097317.1
• Gene: kn / 45318
• FlyBaseID: FBgn0001319
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: XP_030106297.1
• Gene: Ebf4 / 228598
• MGIID: 2385972
• Length: 724
• Species: Mus musculus
• Alignment Length: 648
• Identity: 364/648 - (56%)
• Similarity: 426/648 - (65%)
• Gaps: 129/648 - (19%)

  Fly   139 LYPSAVSGP-----RSAGG-----------------LMFGLPP----------TAAVDMNQ---- 167
            |.|.|.:||     |..||                 |:..|||          |||...::
Mouse    41 LPPGAAAGPGRRGTRGPGGGCVCWPGAGPAFPRDARLLLLLPPRPPPSPPPTSTAAASPSRMDAL 105

  Fly   168 PRGPMTSLKEEP-----LGS--RWAMQP--VVD-----QSNLGIGRAHFEKQPPSNLRKSNFFHF 218
            |||.: .|||||     |||  .| ||.  ::|     ||.:|:.||||||||||||||||||||
Mouse   106 PRGGL-HLKEEPLLPSSLGSVRSW-MQSAGILDSNTAAQSGVGLARAHFEKQPPSNLRKSNFFHF 168

  Fly   219 VIALYDRAGQPIEIERTAFIGFIEKDSESDATKTNNGIQYRLQLLYANGARQEQDIFVRLIDSVT 283
            |:|:|||.|||:|:||||||.|:|||.|....||||||.|||:|:|.||.|.|||::||||||::
Mouse   169 VLAMYDRQGQPVEVERTAFIDFVEKDREPGTEKTNNGIHYRLRLVYNNGLRTEQDLYVRLIDSMS 233

  Fly   284 KQAIIYEGQDKNPEMCRVLLTHEVMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLK 348
            |||||||||||||||||||||||:|||||||:|||||||||||||||||||||||||||||||||
Mouse   234 KQAIIYEGQDKNPEMCRVLLTHEIMCSRCCDRKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLK 298

  Fly   349 NAGNPRDMRRFQVVISTQVAVDGPLLAISDNMFVHNNSKHGRRAKRLDTTEGTGNTSLSISGHPL 413
            ||||||||||||||:||.|:|||.:||:||||||||||||||||:|||.:||..:..
Mouse   299 NAGNPRDMRRFQVVVSTTVSVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGQDSQP-------- 355

  Fly   414 APDSTYDGLYPP-----------LPVATPCIKAISPSEGWTTGGATVIIVGDNFFDGLQVVFGTM 467
            :||....   ||           ||.||||||||||.||||||||||||:|||||||||||||.:
Mouse   356 SPDQLQS---PPWYSPLTWVLSCLPAATPCIKAISPGEGWTTGGATVIIIGDNFFDGLQVVFGNV 417

  Fly   468 LVWSELITSHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGSPGRFVYVSALNEPTIDYGFQRLQKL 532
            |:||||||.||||||||||||||||||||||||||||||:|||||| :||||||||||||||||:
Mouse   418 LLWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFVY-TALNEPTIDYGFQRLQKV 481

  Fly   533 IPRHPGDPEKLQKEIILKRAADL----------------------VEALYSMPRSPG-------- 567
            |||||||||:|.||::|||||||                      .|||||.||:|.
Mouse   482 IPRHPGDPERLPKEVLLKRAADLAEALYGVPSSNQELLLKRAADVAEALYSAPRAPAPLGPLAPS 546

  Fly   568 ----GSTGFNSYAGQLAVSVQDGSGQWTEDDYQRAQSSSVSPRGGYCSSASTPHSSGGSYGA--- 625
                ...|.|:::..||::|.|.:   .|..|.|: ..|.|||     .|.:|.|...|||:
Mouse   547 HPHPAVVGINAFSSPLAIAVGDTT---PEPGYARS-CGSASPR-----FAPSPGSQQSSYGSGLG 602

  Fly   626 --TAASAAVAATANGYAPAPNM--GTLSSSPGSVFNST---SRVSSLSFNPFALPTCNTQGYS 681
              ..:..|...|..|...:|:.  |:.::||.::..|:   :..||:|. |.|.||.:...:|
Mouse   603 AGLGSYGAPGVTGLGVPGSPSFLNGSTATSPFAIMPSSPPLAAASSMSL-PAAAPTTSVFSFS 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kn	NP_001097317.1	COE_DBD	184..395	CDD:212156	171/217 (79%)
		IPT_COE	431..515	CDD:238580	76/83 (92%)
		COE1_HLH	517..560	CDD:293032	36/64 (56%)
Ebf4	XP_030106297.1	COE1_DBD	119..345	CDD:293031	174/226 (77%)
		IPT_COE	381..465	CDD:238580	76/84 (90%)
		COE1_HLH	466..509	CDD:318604	34/42 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849484
Domainoid	1	1.000	374	1.000	Domainoid score	I868
eggNOG	1	0.900	-	-		E1_KOG3836
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	648	1.000	Inparanoid score	I789
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352969at33208
OrthoFinder	1	1.000	-	-		FOG0000764
OrthoInspector	1	1.000	-	-		otm43377
orthoMCL	1	0.900	-	-		OOG6_102533
Panther	1	1.100	-	-	O	PTHR10747
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X577
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.760