Protein Alignment kn and Ebf1

DIOPT Version :9

• Sequence 1: NP_001097317.1
• Gene: kn / 45318
• FlyBaseID: FBgn0001319
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: XP_006246179.1
• Gene: Ebf1 / 116543
• RGDID: 620953
• Length: 592
• Species: Rattus norvegicus
• Alignment Length: 617
• Identity: 370/617 - (59%)
• Similarity: 421/617 - (68%)
• Gaps: 116/617 - (18%)

  Fly   154 MFGLPPTAAVDMNQPRGPMTSLKEEPLGS-----RWAMQ--PVVD-----QSNLGIGRAHFEKQP 206
            |||:..:.     |..|  :|:|||||||     |..||  .|:|     ||.:|:.||||||||
  Rat     1 MFGIQESI-----QRSG--SSMKEEPLGSGMNAVRTWMQGAGVLDANTAAQSGVGLARAHFEKQP 58

  Fly   207 PSNLRKSNFFHFVIALYDRAGQPIEIERTAFIGFIEKDSESDATKTNNGIQYRLQLLYANGARQE 271
            |||||||||||||:|||||.|||:|||||||:||:||:.|:::.||||||.|||||||:||.|.|
  Rat    59 PSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTE 123

  Fly   272 QDIFVRLIDSVTKQAIIYEGQDKNPEMCRVLLTHEVMCSRCCDKKSCGNRNETPSDPVIIDRFFL 336
            ||.:||||||:|||||:||||||||||||||||||:|||||||||||||||||||||||||||||
  Rat   124 QDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFL 188

  Fly   337 KFFLKCNQNCLKNAGNPRDMRRFQVVISTQVAVDGPLLAISDNMFVHNNSKHGRRAKRLDTTEGT 401
            ||||||||||||||||||||||||||:||.|.|||.:||:||||||||||||||||:|||.:|||
  Rat   189 KFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGT 253

  Fly   402 GNTSLSISGHPLAPDSTYDGLYPPLPVATPCIKAISPSEGWTTGGATVIIVGDNFFDGLQVVFGT 466
            .    |...|                .|||||||||||||||||||||||:||||||||||:|||
  Rat   254 P----SYLEH----------------AATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGT 298

  Fly   467 MLVWSELITSHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGSPGRFVYVSALNEPTIDYGFQRLQK 531
            |||||||||.||||||||||||||||||||||||||||||:||||:| :||||||||||||||||
  Rat   299 MLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIY-TALNEPTIDYGFQRLQK 362

  Fly   532 LIPRHPGDPEKLQKEIILKRAADLVEALYSMPRS------------------------------- 565
            :|||||||||:|.||:|||||||||||||.||.:
  Rat   363 VIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALAN 427

  Fly   566 ---PGGSTGFNSYAGQLAVSVQDGSGQWTEDDYQRAQSSSVSPRGGYCSSASTPH--------SS 619
               ..|..|.||::|||||:|.:.| |.|...:.| .||||||. ||..| :||.        :|
  Rat   428 TSVHAGMMGVNSFSGQLAVNVSEAS-QATNQGFTR-NSSSVSPH-GYVPS-TTPQQTNYNSVTTS 488

  Fly   620 GGSYGATAAS--AAVAATANG------YAPAPNMGTLSSSPGSVFNSTSRVSSLSFNPFAL---- 672
            ...||:.|.|  .......||      ||..|:..|::||.....|.:|.....||:|..:
  Rat   489 MNGYGSAAMSNLGGSPTFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAV 553

  Fly   673 -----------------PTC-NTQGYSTQLVT 686
                             ||| :|.|.|.|.::
  Rat   554 KQKSAFAPVVRPQTSPPPTCTSTNGNSLQAIS 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kn	NP_001097317.1	COE_DBD	184..395	CDD:212156	175/217 (81%)
		IPT_COE	431..515	CDD:238580	78/83 (94%)
		COE1_HLH	517..560	CDD:293032	38/42 (90%)
Ebf1	XP_006246179.1	COE1_DBD	21..247	CDD:406750	178/225 (79%)
		IPT_COE	263..347	CDD:238580	78/84 (93%)
		COE1_HLH	348..391	CDD:406751	38/42 (90%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353122
Domainoid	1	1.000	374	1.000	Domainoid score	I843
eggNOG	1	0.900	-	-		E1_KOG3836
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	648	1.000	Inparanoid score	I768
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352969at33208
OrthoFinder	1	1.000	-	-		FOG0000764
OrthoInspector	1	1.000	-	-		otm45447
orthoMCL	1	0.900	-	-		OOG6_102533
Panther	1	1.100	-	-	O	PTHR10747
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X577
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.800