Protein Alignment kn and ebf4

DIOPT Version :10

• Sequence 1: NP_001097317.1
• Gene: kn / 45318
• FlyBaseID: FBgn0001319
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: XP_004912820.1
• Gene: ebf4 / 100492234
• XenbaseID: XB-GENE-6030626
• Length: 604
• Species: Xenopus tropicalis
• Alignment Length: 607
• Identity: 363/607 - (59%)
• Similarity: 414/607 - (68%)
• Gaps: 115/607 - (18%)

  Fly   154 MFGLPPTAAVDMNQPRGPMTSLKEEPLGS-----RWAMQ--PVVD-----QSNLGIGRAHFEKQP 206
            |||:..:.     |..|  ||:|||||..     |..||  .|:|     ||.:|:.||||||||
 Frog     1 MFGIQESI-----QRSG--TSMKEEPLSGGMNAVRTWMQGAGVLDANTAAQSGVGLARAHFEKQP 58

  Fly   207 PSNLRKSNFFHFVIALYDRAGQPIEIERTAFIGFIEKDSESDATKTNNGIQYRLQLLYANGARQE 271
            |||||||||||||:|||||.|||:|||||||:||:|||.|:.:.||||||.|||||||:||.|.|
 Frog    59 PSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKDKETSSEKTNNGIHYRLQLLYSNGIRTE 123

  Fly   272 QDIFVRLIDSVTKQAIIYEGQDKNPEMCRVLLTHEVMCSRCCDKKSCGNRNETPSDPVIIDRFFL 336
            ||.:||||||:|||.|:||||||||||||||||||:|||||||||||||||||||||||||||||
 Frog   124 QDFYVRLIDSMTKQPIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFL 188

  Fly   337 KFFLKCNQNCLKNAGNPRDMRRFQVVISTQVAVDGPLLAISDNMFVHNNSKHGRRAKRLDTTEGT 401
            ||||||||||||||||||||||||||:||.:.|||.:||:||||||||||||||||:|||.::||
 Frog   189 KFFLKCNQNCLKNAGNPRDMRRFQVVVSTTINVDGHVLAVSDNMFVHNNSKHGRRARRLDPSDGT 253

  Fly   402 GNTSLSISGHPLAPDSTYDGLYPPLPVATPCIKAISPSEGWTTGGATVIIVGDNFFDGLQVVFGT 466
            .    |...|                .||||||||||||||||||||||::||||||||||:|||
 Frog   254 P----SYLEH----------------AATPCIKAISPSEGWTTGGATVIVIGDNFFDGLQVIFGT 298

  Fly   467 MLVWSELITSHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGSPGRFVYVSALNEPTIDYGFQRLQK 531
            |||||||||.||||||||||||||||||||||||||||||:||||:| :||||||||||||||||
 Frog   299 MLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIY-TALNEPTIDYGFQRLQK 362

  Fly   532 LIPRHPGDPEKLQKEIILKRAADLVEALYSMPRS--------------------------PG--- 567
            :|||||||||:|.||:|||||||||||||.||.:                          |.
 Frog   363 VIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHSQLPALTN 427

  Fly   568 -----GSTGFNSYAGQLAVSVQDGSGQWTEDDYQRAQSSSVSPRGGYCSSASTPH--------SS 619
                 |..|.||::|||||:|.:.| |.|...:.| .:|||||. .|..| :||.        :|
 Frog   428 SSVHPGMMGVNSFSGQLAVNVSEPS-QVTNQGFSR-NTSSVSPH-SYAPS-TTPQQTNYSSVTTS 488

  Fly   620 GGSYGATAAS--AAVAATANG------YAPAPNMGTLSSSPGSVFNSTSRVSSLSFNPFAL---- 672
            ...||.||.|  |...:..||      ||..|:..|::||.....|.:|.....||:|..:
 Frog   489 MNGYGNTAMSNLAGSPSFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAV 553

  Fly   673 -----------------PTCNT 677
                             |||::
 Frog   554 KQKSAFAPVVRPQASPPPTCSS 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kn	NP_001097317.1	COE_DBD	184..395	CDD:212156	174/217 (80%)
		IPT_COE	431..515	CDD:238580	77/83 (93%)
		COE1_HLH	517..560	CDD:406751	38/42 (90%)
ebf4	XP_004912820.1	COE1_DBD	23..247	CDD:435333	175/223 (78%)
		IPT_COE	263..347	CDD:238580	77/84 (92%)
		COE1_HLH	348..391	CDD:406751	38/42 (90%)