Sequence 1: | NP_001261836.1 | Gene: | fz / 45307 | FlyBaseID: | FBgn0001085 | Length: | 612 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_059108.1 | Gene: | FZD3 / 7976 | HGNCID: | 4041 | Length: | 666 | Species: | Homo sapiens |
Alignment Length: | 533 | Identity: | 219/533 - (41%) |
---|---|---|---|
Similarity: | 299/533 - (56%) | Gaps: | 55/533 - (10%) |
- Green bases have known domain annotations that are detailed below.
Fly 53 CEPITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYVPVCTIL 117
Fly 118 ERPIPPCRSLCESA-RVCEKLMKTYNFNWPENLECSKFP---------VHGGEDLCVAENTTSSA 172
Fly 173 STAATPTRSVAKVTTRKHQTGVESPHRNIGFVCPVQLKTPLGMGYELKVGGKDLH--DCGAPCHA 235
Fly 236 MFFPERERTVLRYWVGSWAAVCVASCLFTVLTFLIDSSRFRYPERAIVFLAVCYLVVGCAYVAGL 300
Fly 301 GAGDSVSCREPFPPPVKLGRLQMMSTITQG-HRQTTSCTVLFMALYFCCMAAFAWWSCLAFAWFL 364
Fly 365 AAGLKWGHEAIENKSHLFHLVAWAVPALQTISVLALAKVEGDILSGVCFVGQLDTHSLGAFLILP 429
Fly 430 LCIYLSIGALFLLAGFISLFRIRTVMKTDGKRTDKLERLMLRIGFFSGLFILPAVGLLGCLFYEY 494
Fly 495 YNFDEWMIQWHRDICKPFSIPCPAARAPGSPEARPIFQIFMVKYLCSMLVGVTSSVWLYSSKTMV 559
Fly 560 SWRNFVERLQGKE 572 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
fz | NP_001261836.1 | CRD_FZ1_like | 51..167 | CDD:143567 | 54/123 (44%) |
Frizzled | 237..564 | CDD:279827 | 143/327 (44%) | ||
FZD3 | NP_059108.1 | CRD_FZ3 | 24..150 | CDD:143558 | 54/125 (43%) |
7tmF_FZD3 | 192..512 | CDD:320161 | 145/330 (44%) | ||
TM helix 1 | 201..226 | CDD:320161 | 10/24 (42%) | ||
TM helix 2 | 235..256 | CDD:320161 | 9/20 (45%) | ||
TM helix 3 | 287..313 | CDD:320161 | 13/25 (52%) | ||
TM helix 4 | 330..352 | CDD:320161 | 10/21 (48%) | ||
TM helix 5 | 366..391 | CDD:320161 | 8/24 (33%) | ||
TM helix 6 | 419..444 | CDD:320161 | 12/24 (50%) | ||
TM helix 7 | 473..498 | CDD:320161 | 10/27 (37%) | ||
Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 502..507 | 2/4 (50%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 538..666 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
Hieranoid | 1 | 1.000 | - | - | ||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D167933at33208 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 1 | 1.100 | - | - | LDO | PTHR11309 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 1 | 1.000 | - | - | X126 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
6 | 5.920 |