Protein Alignment fz and szl

DIOPT Version :10

• Sequence 1: NP_001261836.1
• Gene: fz / 45307
• FlyBaseID: FBgn0001085
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_858049.1
• Gene: szl / 353294
• ZFINID: ZDB-GENE-030530-1
• Length: 282
• Species: Danio rerio
• Alignment Length: 292
• Identity: 76/292 - (26%)
• Similarity: 119/292 - (40%)
• Gaps: 85/292 - (29%)

  Fly    52 RCEPI--TISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYVPVC 114
            ||.||  .:|:|:::||:...:|||:||...|||.........|:..||....:.|:|||..|||
Zfish    26 RCVPIPPQMSVCQDVPYSEMRLPNLLGHGSLEEAAPRSDDLRTLLHTGCHPQARAFVCSLIAPVC 90

  Fly   115 TILERPIPPCRSLCESAR-VCEKLMKTYNFNWPENLECSKFPVHGGEDLCVAENTTSSASTAATP 178
              |:|.|.||||:|.:.: .|..::..:..:|||:|.|.:||   .:|.|:            ||
Zfish    91 --LDRFIQPCRSVCLAVKESCSPVLACHGHSWPESLNCERFP---EQDDCL------------TP 138

  Fly   179 -TRSVAKVTTRKHQTGVESPHRNIGFVCP-VQ----LKTPLGM----GYELKV------------ 221
             .:.::..:....|...:|        || ||    |||.|..    .:.:||
Zfish   139 LPKHISAFSKEFPQPACQS--------CPSVQESPSLKTLLDSLCLNDFAVKVKIMRRRVPSSEP 195

  Fly   222 -----GGKDLHDCGAPCHAMFFPERERTVLRYWVGSWAAVCVASCLFTVLTFLIDSSRFRYPERA 281
                 |..:|.:.|.     ..|....::|:.|:     :....|...::.          |.||
Zfish   196 EFTVEGAVELIERGP-----LMPYDTASLLQRWM-----LINLRCAHALVR----------PGRA 240

  Fly   282 IVFLAVCYLVVGCAYVAGLGAGDSVSCREPFP 313
            .:     ||:.|     .:.||.|:.....||
Zfish   241 QL-----YLITG-----KMRAGGSIEIANLFP 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fz	NP_001261836.1	CRD_FZ1_like	51..167	CDD:143567	44/117 (38%)
		7tmF_FZD1_insect	236..568	CDD:320376	15/78 (19%)
		TM helix 1	245..270	CDD:320376	3/24 (13%)
		TM helix 2	279..300	CDD:320376	5/20 (25%)
		TM helix 3	338..364	CDD:320376
		TM helix 4	381..397	CDD:320376
		TM helix 5	419..448	CDD:320376
		TM helix 6	468..495	CDD:320376
		TM helix 7	527..552	CDD:320376
szl	NP_858049.1	CRD_FZ	19..158	CDD:470581	48/156 (31%)
		NTR_Sfrp1_like	152..282	CDD:239635	30/149 (20%)