| Sequence 1: | NP_001261836.1 | Gene: | fz / 45307 | FlyBaseID: | FBgn0001085 | Length: | 612 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_032083.3 | Gene: | Fzd7 / 14369 | MGIID: | 108570 | Length: | 572 | Species: | Mus musculus |
| Alignment Length: | 562 | Identity: | 272/562 - (48%) |
|---|---|---|---|
| Similarity: | 351/562 - (62%) | Gaps: | 42/562 - (7%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 23 PLD--ASPYYRSGGGLMASSGTELDGLPHHNRCEPITISICKNIPYNMTIMPNLIGHTKQEEAGL 85
Fly 86 EVHQFAPLVKIGCSDDLQLFLCSLYVPVCTILERPIPPCRSLCESARV-CEKLMKTYNFNWPENL 149
Fly 150 ECSKFPVHGGEDLCVAENTT-SSASTAATPTRSVAKVTTRKHQTGVESPHRNIG-----FVCPVQ 208
Fly 209 LKTPLGMGYELKVGGKDLHDCGAPCH------AMFFPERERTVLRYWVGSWAAVCVASCLFTVLT 267
Fly 268 FLIDSSRFRYPERAIVFLAVCYLVVGCAYVAGLGAGDSVSCREPFPPPVKLGRLQMMSTITQGHR 332
Fly 333 QTTSCTVLFMALYFCCMAAFAWWSCLAFAWFLAAGLKWGHEAIENKSHLFHLVAWAVPALQTISV 397
Fly 398 LALAKVEGDILSGVCFVGQLDTHSLGAFLILPLCIYLSIGALFLLAGFISLFRIRTVMKTDGKRT 462
Fly 463 DKLERLMLRIGFFSGLFILPAVGLLGCLFYEYYNFDEWMIQWHRDICKPFSIPCPAAR-APGSPE 526
Fly 527 ARPIFQIFMVKYLCSMLVGVTSSVWLYSSKTMVSWRNFVERL 568 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| fz | NP_001261836.1 | CRD_FZ1_like | 51..167 | CDD:143567 | 71/116 (61%) |
| Frizzled | 237..564 | CDD:279827 | 165/327 (50%) | ||
| Fzd7 | NP_032083.3 | CRD_FZ7 | 45..169 | CDD:143575 | 74/123 (60%) |
| 7tmF_FZD7 | 241..571 | CDD:320374 | 169/334 (51%) | ||
| TM helix 1 | 250..275 | CDD:320374 | 14/24 (58%) | ||
| TM helix 2 | 284..305 | CDD:320374 | 11/20 (55%) | ||
| TM helix 3 | 335..361 | CDD:320374 | 13/25 (52%) | ||
| TM helix 4 | 378..394 | CDD:320374 | 11/15 (73%) | ||
| TM helix 5 | 416..445 | CDD:320374 | 14/28 (50%) | ||
| TM helix 6 | 465..492 | CDD:320374 | 15/26 (58%) | ||
| TM helix 7 | 521..546 | CDD:320374 | 12/28 (43%) | ||
| Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 550..555 | 2/4 (50%) | |||
| PDZ-binding | 570..572 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 158 | 1.000 | Domainoid score | I4103 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 528 | 1.000 | Inparanoid score | I1213 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S3599 |
| OMA | 1 | 1.010 | - | - | QHG48699 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0001848 | |
| OrthoInspector | 1 | 1.000 | - | - | otm43585 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104642 | |
| Panther | 1 | 1.100 | - | - | O | PTHR11309 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3233 |
| SonicParanoid | 1 | 1.000 | - | - | X126 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 14 | 13.810 | |||||