Sequence 1: | NP_001261836.1 | Gene: | fz / 45307 | FlyBaseID: | FBgn0001085 | Length: | 612 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_009128.1 | Gene: | FZD10 / 11211 | HGNCID: | 4039 | Length: | 581 | Species: | Homo sapiens |
Alignment Length: | 587 | Identity: | 230/587 - (39%) |
---|---|---|---|
Similarity: | 329/587 - (56%) | Gaps: | 77/587 - (13%) |
- Green bases have known domain annotations that are detailed below.
Fly 34 GGLMASSGTELDGLPHHNRCEPITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGC 98
Fly 99 SDDLQLFLCSLYVPVCT-ILERPIPPCRSLCESARV-CEKLMKTYNFNWPENLECSKFPVHGGED 161
Fly 162 -LCV-AENTTSSASTAATPTRSVAKVTTRKHQTGVESPHRNIGFVCPV--QLKTPLGMGYELKVG 222
Fly 223 GKDLHDCGAP-----------CHAM-------FFPERERTVLRYWVGSWAAVCVASCLFTVLTFL 269
Fly 270 IDSSRFRYPERAIVFLAVCYLVVGCAYVAGLGAG-DSVSC-REPFPPPVKLGRLQMMSTITQGHR 332
Fly 333 QTTSCTVLFMALYFCCMAAFAWWSCLAFAWFLAAGLKWGHEAIENKSHLFHLVAWAVPALQTISV 397
Fly 398 LALAKVEGDILSGVCFVGQLDTHSLGAFLILPLCIYLSIGALFLLAGFISLFRIRTVMKTDGKRT 462
Fly 463 DKLERLMLRIGFFSGLFILPAVGLLGCLFYEYYNFDEWMIQWHRDICK----PFSIPCPAARAPG 523
Fly 524 SPEARPIFQIFMVKYLCSMLVGVTSSVWLYSSKTMVSWRNFVERLQGKEPRTRAQAYVXYETGPA 588
Fly 589 GG 590 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
fz | NP_001261836.1 | CRD_FZ1_like | 51..167 | CDD:143567 | 60/119 (50%) |
Frizzled | 237..564 | CDD:279827 | 148/332 (45%) | ||
FZD10 | NP_009128.1 | CRD_FZ10 | 30..156 | CDD:143571 | 62/149 (42%) |
7tmF_FZD10 | 217..535 | CDD:320165 | 148/334 (44%) | ||
TM helix 1 | 226..251 | CDD:320165 | 11/24 (46%) | ||
TM helix 2 | 260..281 | CDD:320165 | 9/20 (45%) | ||
TM helix 3 | 310..336 | CDD:320165 | 10/25 (40%) | ||
TM helix 4 | 353..369 | CDD:320165 | 10/15 (67%) | ||
TM helix 5 | 391..420 | CDD:320165 | 12/28 (43%) | ||
TM helix 6 | 440..467 | CDD:320165 | 14/26 (54%) | ||
TM helix 7 | 497..522 | CDD:320165 | 10/24 (42%) | ||
Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 526..531 | 2/4 (50%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 560..581 | ||||
PDZ-binding | 579..581 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 1 | 1.000 | - | - | X126 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.810 |