DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fz and sfrp2l

DIOPT Version :9

Sequence 1:	NP_001261836.1	Gene:	fz / 45307	FlyBaseID:	FBgn0001085	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_001373251.1	Gene:	sfrp2l / 100538205	ZFINID:	ZDB-GENE-061122-2	Length:	250	Species:	Danio rerio

Alignment Length:	191	Identity:	61/191 - (31%)
Similarity:	83/191 - (43%)	Gaps:	18/191 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 ICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYVPVC-TILERPIPP 123
            :|..|.|....:|||:.|....||..:...:.||:...|..|.:.|||||:.||| ..:..|:.|
Zfish     3 LCFGIGYREMRLPNLLEHQSAREAQQQSAAWVPLIGKRCHRDTRRFLCSLFAPVCLPEVPTPVSP 67

  Fly   124 CRSLCESAR-VCEKLMKTYNFNWPENLECSKFPVHGGEDLCV-AENTTSSASTAATPTRSVAKVT 186
            ||:||.:.| .|..:|..:.|.|||...||:|.  .|.:||: .|.....|.|...||.|  ::.
Zfish    68 CRNLCVAVRDACAPVMSAFGFPWPEMFNCSRFT--DGPELCIPGEIDPLRAPTTLAPTGS--EIC 128

  Fly   187 TRKHQTGVESPHRNIGFVCPVQLKTPLGMGYELKVGGKDLHDCGAPCHAMFFPERERTVLR 247
            ......| :.....:...|..|....|.:| ...|.|.||.         .|||....|||
Zfish   129 EACSADG-DGEREILQEFCTAQFVVRLRVG-SCSVIGSDLR---------VFPEGRSRVLR 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fz	NP_001261836.1	CRD_FZ1_like	51..167	CDD:143567	40/109 (37%)
fz	NP_001261836.1	Frizzled	237..564	CDD:279827	6/11 (55%)
sfrp2l	NP_001373251.1	CRD_FZ	1..108	CDD:413323	40/106 (38%)
sfrp2l	NP_001373251.1	NTR_like	125..250	CDD:413349	16/67 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910