Protein Alignment Dr and HGTX

DIOPT Version :10

• Sequence 1: NP_477324.1
• Gene: Dr / 45285
• FlyBaseID: FBgn0000492
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 496
• Identity: 123/496 - (24%)
• Similarity: 171/496 - (34%)
• Gaps: 156/496 - (31%)

  Fly    43 SGSNSGSNMSSGNMTSSNLTNLSPSHPAGLNALASP-TSPSALLLAHQQHLLQQHQQHQQQQQQQ 106
            :.:|:.:|.||.|..||.|..|..:|..||....|| |:|
  Fly   144 NNNNNNNNNSSNNNNSSPLMLLKAAHGGGLKDSDSPSTTP------------------------- 183

  Fly   107 QQAAALQLAAVHPPAHHLHKTTSRLSNFSVASLLADTRPRTPPNQA--ADGPQNLT----SSAAT 165
                        |||      :|||.:.|..|      ||...|.:  .|..::..    ||.|.
  Fly   184 ------------PPA------SSRLHSDSSPS------PRYEHNSSPGVDSAKSYALSQRSSGAE 224

  Fly   166 SPISQASSTPPPPPASAAAQVPANTFHPAAVAHHAH------LLQAAHAAAAA------HAQHQA 218
            .| .|.|.:..|||.......|.|.....|...|.|      |..|.||....      |..|:.
  Fly   225 DP-CQTSESASPPPQGQNDYSPENLSSQRAKFQHHHGVNPLALHNANHAGNPGCHNNNNHMDHKL 288

  Fly   219 MAAQLRQQQQQADARANSPPASTSSTPSSTPLGSALGSQGNVASTPAKNERHSPLGSHTDSELEY 283
            ..:.|            .||.:...:.::...|..:|  |:.||....:..||| .||..|:
  Fly   289 PLSFL------------GPPLAALHSMTTEMKGQGVG--GSSASANGLSYSHSP-NSHLISD--- 335

  Fly   284 DEEMLQDHEADHDEEEDSIVDIEDMNADDSPRSTPDGLDGSGKSLESPHG-------PPPGSHMQ 341
                    .........|.....:.|:..:|               :|||       |||   :.
  Fly   336 --------RGSGGSSSSSSTTTTNTNSQGAP---------------NPHGIDTILSKPPP---VT 374

  Fly   342 STILSPAALASGHVPIRPTPFSALAAAA--VAWTGMGGGVP---------------WPGTRQMPP 389
            |..||  ||....:|    .||..||||  ..:.....|.|               |||.:.:..
  Fly   375 SAGLS--ALTGAGIP----RFSIAAAAAGMAQYLSQSQGAPLKTHAGHIVDRTHLYWPGLQGLVA 433

  Fly   390 FGPPGMFPGAGFGGDAN-------EPPRIKCNLRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLS 447
             .|............||       .|...|...:||     .|..|:.||:.:|||.|.:.:||:
  Fly   434 -NPIAWRERLSNTMSANLSQSHQHHPSNDKDGKKKH-----TRPTFSGQQIFALEKTFEQTKYLA 492

  Fly   448 IAERAEFSSSLRLTETQVKIWFQNRRAKAKRLQEAEIEKIK 488
            ..|||:.:.:|.::|:|||:||||||.|.::...||:...|
  Fly   493 GPERAKLAYALGMSESQVKVWFQNRRTKWRKRHAAEMATAK 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dr	NP_477324.1	Homeodomain	422..478	CDD:459649	25/55 (45%)
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	64/308 (21%)
		Homeodomain	465..523	CDD:459649	27/62 (44%)