Protein Alignment Dr and LOC4576841

DIOPT Version :10

• Sequence 1: NP_477324.1
• Gene: Dr / 45285
• FlyBaseID: FBgn0000492
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: XP_001230938.4
• Gene: LOC4576841 / 4576841
• VectorBaseID: AGAMI1_003921
• Length: 540
• Species: Anopheles gambiae
• Alignment Length: 631
• Identity: 143/631 - (22%)
• Similarity: 200/631 - (31%)
• Gaps: 254/631 - (40%)

  Fly    19 TSPTVPPSSNTPAGNLIITSSSSNS--GSNSGSNMSSGNMTSSNLTNLSPSHPAGLNALASPTSP 81
            :||  ||..::|||:.|...|.|..  ||.|                   :|||.|      ..|
Mosquito    17 SSP--PPPCSSPAGSEISVGSPSPPPIGSES-------------------AHPAHL------PHP 54

  Fly    82 SALLLAHQQH---LLQQHQQHQQQQQQQQQAAALQLAAVHPPAHHLHKTTSRL------------ 131
            ..|.:.|..|   |:..|..|                  ||.|.|.|...|.|
Mosquito    55 HPLAVTHLVHHHPLVHPHHPH------------------HPAALHAHAAVSALQARAEDYFTPLK 101

  Fly   132 --------SNFSVA---------SLLADTRPRTPPNQAAD-----GPQN------------LTSS 162
                    |...:|         |....:.|.||.|.|:.     .|.|            .|||
Mosquito   102 RLRMVEGGSGVELASPPGGSPKESTSRGSSPTTPINSASSANTVTSPNNSGNSATTLTTSTTTSS 166

  Fly   163 AATSPIS--------------------------QASSTPPPPPASAAAQVPANTFHPAAVA-HHA 200
            ..|.|.|                          :.:..|.|||.:.|       .|.|::: ||.
Mosquito   167 NTTKPSSGSTAAEGVKSFSIADILGRDAEAASREGAREPSPPPINPA-------LHHASLSHHHL 224

  Fly   201 HLL---QAAHAAAAAHAQHQAMAAQLRQQ------------QQQADARANSPPASTSSTPSSTPL 250
            ||.   .|||.|||.|..|...::...||            :.....|...|||
Mosquito   225 HLTGHHPAAHLAAAHHHHHHHHSSSTLQQAASKIVRPWDHLRGPIPVRPFLPPA----------- 278

  Fly   251 GSALGSQGNVASTPAKNERHSPLGSHTDSELEYDEEMLQD---HEADHDEEEDSIVDI------- 305
              .|..:..:|.     :.|..|..|..::.:....|..|   .|:..:....:..|.
Mosquito   279 --LLHYEHRLAL-----DYHQQLQEHFRAQAQLLRHMSMDIIPSESGSERSSSAASDCCSPEIGR 336

  Fly   306 -EDMNADDSPRSTPDGL--------DGSGKSLESPHGPPPGSHMQSTILSPAALASGHVPIRPTP 361
             .|..:..|.:|:..|:        ||||:|     |...|:       |.||.:........||
Mosquito   337 GSDHQSHQSSQSSSSGVGGGSAGAGDGSGRS-----GANGGA-------SGAAKSGSKTAPNGTP 389

  Fly   362 FSALAAAAVAWTGMGGGVPWPGTRQMPPFGPPGMFPGAGFGGDANEPPRIKCNLRKHKP----NR 422
            ..||.                   ||         ....|.....:..:...||..::|    .|
Mosquito   390 LDALF-------------------QM---------TNKNFDESNEDSEQSHLNLFANRPQPKKKR 426

  Fly   423 KPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWFQNRRAKAKRLQE---AEI 484
            |.||.||..|:..|||:|..::|||.::|.|.:::|.|:..||..||||||||.||..|   .::
Mosquito   427 KSRTAFTNHQIFELEKRFLYQKYLSPSDRDEIAAALGLSNAQVITWFQNRRAKLKRDMEELKKDV 491

  Fly   485 EKIKMAALGR---------------------GAPGAQWAMAGYFHP 509
            |.:|:.:..:                     |:|    ..|.:.||
Mosquito   492 ETVKVLSAHKTFLENVNDMNILKKKIMHDDGGSP----QNASFLHP 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dr	NP_477324.1	Homeodomain	422..478	CDD:459649	28/55 (51%)
LOC4576841	XP_001230938.4	None