Protein Alignment Dr and MSX2

DIOPT Version :9

• Sequence 1: NP_477324.1
• Gene: Dr / 45285
• FlyBaseID: FBgn0000492
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_002440.2
• Gene: MSX2 / 4488
• HGNCID: 7392
• Length: 267
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 101/228 - (44%)
• Similarity: 118/228 - (51%)
• Gaps: 61/228 - (26%)

  Fly   296 DEEEDSIVDIEDMNADDSPRSTPDGLDG--------------SGKSLESPHGPP----------- 335
            |||..::|        ..|...|.|.:|              |.::|.|...||
Human    14 DEEGPAVV--------AGPGPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPKEASPLPAESA 70

  Fly   336 -PGSHMQSTILSPAALASGHVP---IRPTPFSALAAAAVAWTGMGGGVPW---PGTRQMPPFGPP 393
             .|:.::..:||.......|.|   ::|     ...|:|.......|..|   || |..||  |.
Human    71 SAGATLRPLLLSGHGAREAHSPGPLVKP-----FETASVKSENSEDGAAWMQEPG-RYSPP--PR 127

  Fly   394 GMFPGAGFGGDANEPPRIKCNLRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSL 458
            .|.|             ..|.|||||.||||||||||.|||:||:|||:||||||||||||||||
Human   128 HMSP-------------TTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSL 179

  Fly   459 RLTETQVKIWFQNRRAKAKRLQEAEIEKIKMAA 491
            .||||||||||||||||||||||||:||:||||
Human   180 NLTETQVKIWFQNRRAKAKRLQEAELEKLKMAA 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dr	NP_477324.1	Homeobox	424..477	CDD:278475	47/52 (90%)
MSX2	NP_002440.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		13/64 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..147		18/46 (39%)
		Homeobox	145..199	CDD:365835	48/53 (91%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157214
Domainoid	1	1.000	107	1.000	Domainoid score	I6524
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000776
OrthoInspector	1	1.000	-	-		otm41028
orthoMCL	1	0.900	-	-		OOG6_109202
Panther	1	1.100	-	-	O	PTHR24338
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2894
SonicParanoid	1	1.000	-	-		X657
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.730