Protein Alignment Dr and HOXD1

DIOPT Version :10

• Sequence 1: NP_477324.1
• Gene: Dr / 45285
• FlyBaseID: FBgn0000492
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_078777.1
• Gene: HOXD1 / 3231
• HGNCID: 5132
• Length: 328
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 87/335 - (25%)
• Similarity: 115/335 - (34%)
• Gaps: 126/335 - (37%)

  Fly   167 PISQASSTPPPPPASAAAQVPANTFHPAAVAHHAHLLQAAHAAAAAHAQHQAMAAQLRQQQQQAD 231
            |::.|..:|.||.|.|...||.    |||..:....|:.|:
Human    55 PLAAARPSPSPPAAPARPSVPP----PAAPQYAQCTLEGAY------------------------ 91

  Fly   232 ARANSPPASTSSTPSSTPLGSALGSQ-GNVASTPAKNERHSPLGSHTDSELEYDEEMLQDHEADH 295
                        .|.:.|..:|.|:. |.:.|.||                 ||...:....||
Human    92 ------------EPGAAPAAAAGGADYGFLGSGPA-----------------YDFPGVLGRAAD- 126

  Fly   296 DEEEDSIVDIEDMNADDSPRSTPDGLDGSGKSLESPHGPPPGSHMQ---STILSPAA--LASGHV 355
                                      ||             |||:.   |.:.|...  |.||.|
Human   127 --------------------------DG-------------GSHVHYATSAVFSGGGSFLLSGQV 152

  Fly   356 PI----RPTPFSA-LAAAAVAWTG-MGGGVPWPGTRQMPPFGPPGMFPGAGFGG--DANEPPRIK 412
            ..    .|.||.| |.|:|....| .....|.|||.      |..:.|.:|...  ...|..::|
Human   153 DYAAFGEPGPFPACLKASADGHPGAFQTASPAPGTY------PKSVSPASGLPAAFSTFEWMKVK 211

  Fly   413 CNLRKH---------KPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIW 468
            .|..|.         .|:...||.|:|:||..|||:|...:||:.|.|.|.::.|.|.:||||||
Human   212 RNASKKGKLAEYGAASPSSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIW 276

  Fly   469 FQNRRAKAKR 478
            |||||.|.|:
Human   277 FQNRRMKQKK 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dr	NP_477324.1	Homeodomain	422..478	CDD:459649	29/55 (53%)
HOXD1	NP_078777.1	Antp-type hexapeptide	204..209		1/4 (25%)
		Homeodomain	233..286	CDD:459649	29/52 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..328