Protein Alignment Dr and HOXC11

DIOPT Version :10

• Sequence 1: NP_477324.1
• Gene: Dr / 45285
• FlyBaseID: FBgn0000492
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_055027.1
• Gene: HOXC11 / 3227
• HGNCID: 5123
• Length: 304
• Species: Homo sapiens
• Alignment Length: 337
• Identity: 77/337 - (22%)
• Similarity: 111/337 - (32%)
• Gaps: 98/337 - (29%)

  Fly   162 SAATSPISQASSTPPPPPASAAAQVP-----ANTFHPAAVAHHAHLLQAAHAAAAAHAQHQAMAA 221
            |..:|.:.||.|.....|.|  ||||     :....|:...||.:...:.:|||......:.:
Human    45 STVSSFLPQAPSRQISYPYS--AQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECL-- 105

  Fly   222 QLRQQQQQADARANSPPASTSSTPSSTPLGSALGSQGNVASTPAKNERHSPLGSHTD-----SEL 281
                           ||::.:..     |....||.|.         .|.|...|..     |.:
Human   106 ---------------PPSTVTEI-----LMKNEGSYGG---------HHHPSAPHATPAGFYSSV 141

  Fly   282 EYDEEMLQDHEADHDEEEDSIVDIEDMNADDSPRSTPDGLDGSGKSLESPHGPPPGSHMQSTILS 346
            ..:..:.|..        |...|.......|.|...|  ..|.|::...|..||...      |:
Human   142 NKNSVLPQAF--------DRFFDNAYCGGGDPPAEPP--CSGKGEAKGEPEAPPASG------LA 190

  Fly   347 PAALASGHVPI---RPTPFSALAAAAVAWTGMGGGVPWPGTRQMPPFGPPGMFPGAGFGGDANEP 408
            ..|.|......   ...|.|:.:|.:||.....|..|                          ..
Human   191 SRAEAGAEAEAEEENTNPSSSGSAHSVAKEPAKGAAP--------------------------NA 229

  Fly   409 PRIKCNLRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWFQNRR 473
            ||          .||.|.|::..|:..||::|....|::..:|.:.|..|.||:.||||||||||
Human   230 PR----------TRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRR 284

  Fly   474 AKAKRLQEAEIE 485
            .|.|:|....::
Human   285 MKEKKLSRDRLQ 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dr	NP_477324.1	Homeodomain	422..478	CDD:459649	25/55 (45%)
HOXC11	NP_055027.1	DUF3528	42..161	CDD:432284	30/156 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..237		21/114 (18%)
		Homeodomain	233..289	CDD:459649	25/55 (45%)