DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Dr and dlx6a

DIOPT Version :9

Sequence 1:NP_477324.1 Gene:Dr / 45285 FlyBaseID:FBgn0000492 Length:515 Species:Drosophila melanogaster
Sequence 2:NP_571398.1 Gene:dlx6a / 30586 ZFINID:ZDB-GENE-980526-448 Length:247 Species:Danio rerio


Alignment Length:266 Identity:74/266 - (27%)
Similarity:97/266 - (36%) Gaps:110/266 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly   234 ANSPPASTSSTPSSTPLGSALGSQGNVASTPAKNERHSPL-----GSHTDSELEYDEEMLQDHEA 293
            |:...|..||..:....|....||   .|:|:....|.||     |||              |..
Zfish     8 ADGLEAQDSSKSAFMEFGQQSHSQ---QSSPSMAASHYPLHCLHSGSH--------------HHH 55

  Fly   294 DHDEEEDSIVDIEDMNADDSPRSTPDGLDGSGKSL-----ESPHGPP--PGSHMQSTILSPAALA 351
            .|               |.||.|   |.:...:||     ..||..|  |..|..         |
Zfish    56 QH---------------DSSPYS---GSNSYNRSLPYSYVSHPHHSPYLPSYHSN---------A 93

  Fly   352 SGHVPIRPTPFSALAAAAVAWTGMGGGVPWPGTRQMPPFGPPGMFPGAGFGGDANEPPR------ 410
            ||                            ..||.                 ||.|..:      
Zfish    94 SG----------------------------TQTRL-----------------DATEQQKTTVIEN 113

  Fly   411 --IKCNLRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWFQNRR 473
              |:.| .|.|..|||||.:::.||.:|..:|::.|||::.||||.::||.||:|||||||||:|
Zfish   114 GEIRFN-GKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKR 177

  Fly   474 AKAKRL 479
            :|.|:|
Zfish   178 SKFKKL 183

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DrNP_477324.1 Homeobox 424..477 CDD:278475 29/52 (56%)
dlx6aNP_571398.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 22..66 18/78 (23%)
Homeobox 128..181 CDD:278475 29/52 (56%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0850
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.810

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