DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dr and dlx3b

DIOPT Version :9

Sequence 1:	NP_477324.1	Gene:	Dr / 45285	FlyBaseID:	FBgn0000492	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_571397.2	Gene:	dlx3b / 30585	ZFINID:	ZDB-GENE-980526-280	Length:	269	Species:	Danio rerio

Alignment Length:	202	Identity:	60/202 - (29%)
Similarity:	90/202 - (44%)	Gaps:	54/202 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   352 SGHVPIRPTPFSALAAAAVAWTGMG---------GGVPWPGTRQMPPF---------GPPGMFPG 398
            ||.:...||...:......:.|.||         ...|:|  :||..:         ..||.:|.
Zfish    18 SGSMSCHPTSKDSPTLPESSATDMGYYSSHHEYYQSPPYP--QQMNSYHQFNLSGMGATPGAYPT 80

  Fly   399 ------------AGFGGDANEPPR----------IKCNLRKHKPNRKPRTPFTTQQLLSLEKKFR 441
                        ..:..|...||:          ::....|.|..|||||.:::.||.:|:::|:
Zfish    81 KTEYPYNTYRQYGHYNRDLQTPPQSAVKEEPETEVRMVNGKPKKIRKPRTIYSSYQLAALQRRFQ 145

  Fly   442 EKQYLSIAERAEFSSSLRLTETQVKIWFQNRRAKAKRLQ---EAEIEKIKMAALGRGAPGAQWAM 503
            :.|||::.||||.::.|.||:|||||||||||:|.|:|.   |..:|.         :|.|..:|
Zfish   146 KAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEH---------SPNASDSM 201

  Fly   504 AGYFHPS 510
            |....||
Zfish   202 ACNSPPS 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dr	NP_477324.1	Homeobox	424..477	CDD:278475	29/52 (56%)
dlx3b	NP_571397.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..41		5/22 (23%)
		DLL_N	28..104	CDD:289198	12/77 (16%)
		Homeobox	128..181	CDD:278475	29/52 (56%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	191..242		7/27 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	250..269
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810