DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Dr and emx2

DIOPT Version :9

Sequence 1:NP_477324.1 Gene:Dr / 45285 FlyBaseID:FBgn0000492 Length:515 Species:Drosophila melanogaster
Sequence 2:NP_571355.2 Gene:emx2 / 30537 ZFINID:ZDB-GENE-990415-54 Length:247 Species:Danio rerio


Alignment Length:211 Identity:68/211 - (32%)
Similarity:90/211 - (42%) Gaps:40/211 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   305 IEDMNADDSPRSTPDGLDGSGKSLESPHGPPPGSHMQSTILSP-------------------AAL 350
            ||.:.|.|:|..       |.:| |.|..|...|:..|:.::|                   .|.
Zfish    12 IESLVAKDNPLP-------SSRS-EEPIRPAALSYANSSQMNPFLNGFHSSGRGVYSNPGLVFAE 68

  Fly   351 ASGHVPIRPTPFSAL----AAAAVAWTGMGGGVPWPGTRQMPP--FGP----PGMFPGAGFGGDA 405
            |..|.|....|..::    |.||...:......|...::|..|  |.|    ...:.|..|.|:.
Zfish    69 AVSHPPNSAVPVHSVPPPHALAAHPLSSSHSPHPLFASQQRDPSTFYPWLIHRYRYLGHRFQGNE 133

  Fly   406 NEPPR-IKCNLRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWF 469
            ..|.. :..|....||.| .||.|:..|||.||..|.:..|:..|||.:.:.||.|||||||:||
Zfish   134 TSPESFLLHNALARKPKR-IRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWF 197

  Fly   470 QNRRAKAKRLQEAEIE 485
            ||||.|.|| |:.|.|
Zfish   198 QNRRTKFKR-QKLEEE 212

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DrNP_477324.1 Homeobox 424..477 CDD:278475 29/52 (56%)
emx2NP_571355.2 Homeobox 153..205 CDD:278475 29/51 (57%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0850
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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