DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dr and Vax1

DIOPT Version :9

Sequence 1:	NP_477324.1	Gene:	Dr / 45285	FlyBaseID:	FBgn0000492	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_033527.1	Gene:	Vax1 / 22326	MGIID:	1277163	Length:	338	Species:	Mus musculus

Alignment Length:	196	Identity:	59/196 - (30%)
Similarity:	84/196 - (42%)	Gaps:	65/196 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   374 GMGGGVPWPGTRQMPPFGPPGMFPGAGFGGDANEPP-----------RI-----KCNLRK----- 417
            |..|.:|....::     |.|.|.|:|...|.|:..           ||     |.::|:
Mouse    34 GAEGSLPAAFLKE-----PQGAFSGSGASEDCNKSKSNSSADPDYCRRILVRDAKGSIREIILPK 93

  Fly   418 ----HKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWFQNRRAKAKR 478
                .:|.| .||.||.:||..||.:|:..||:...||.|.:..|.|:|||||:||||||.|.|:
Mouse    94 GLDLDRPKR-TRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKK 157

  Fly   479 LQ--EAEIEKI-----------KMAALGR----------------GAPGAQWAMAGYFHPSLMHL 514
            .|  ::|:..:           ::...||                ||.|:  |:.|   |||..|
Mouse   158 DQGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATGALGS--ALRG---PSLPAL 217

  Fly   515 G 515
            |
Mouse   218 G 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dr	NP_477324.1	Homeobox	424..477	CDD:278475	28/52 (54%)
Vax1	NP_033527.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..69		10/39 (26%)
		Homeobox	103..156	CDD:306543	28/52 (54%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	239..269
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	318..338
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810