Protein Alignment Dr and EMX2

DIOPT Version :10

• Sequence 1: NP_477324.1
• Gene: Dr / 45285
• FlyBaseID: FBgn0000492
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_004089.1
• Gene: EMX2 / 2018
• HGNCID: 3341
• Length: 252
• Species: Homo sapiens
• Alignment Length: 227
• Identity: 73/227 - (32%)
• Similarity: 91/227 - (40%)
• Gaps: 67/227 - (29%)

  Fly   305 IEDMNADDSPRSTPDGLDGSGKSLESPHGPPPGSHMQSTILSP--------AALASGH------- 354
            ||.:.|.|||      |..|..  |.|..|...|:..|:.::|        ||.|:|.
Human    12 IESLVAKDSP------LPASRS--EDPIRPAALSYANSSPINPFLNGFHSAAAAAAGRGVYSNPD 68

  Fly   355 --------------VPIRPT-PFSALAAAAVAWTGMGGGVPWPGTRQMPPF------GPPGMFP- 397
                          ||:.|. |..||||.           |.|.:....|.      .|...:|
Human    69 LVFAEAVSHPPNPAVPVHPVPPPHALAAH-----------PLPSSHSPHPLFASQQRDPSTFYPW 122

  Fly   398 --------GAGFGGDANEPPR-IKCNLRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAE 453
                    |..|.|:...|.. :..|....||.| .||.|:..|||.||..|.:..|:..|||.:
Human   123 LIHRYRYLGHRFQGNDTSPESFLLHNALARKPKR-IRTAFSPSQLLRLEHAFEKNHYVVGAERKQ 186

  Fly   454 FSSSLRLTETQVKIWFQNRRAKAKRLQEAEIE 485
            .:.||.|||||||:||||||.|.|| |:.|.|
Human   187 LAHSLSLTETQVKVWFQNRRTKFKR-QKLEEE 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dr	NP_477324.1	Homeodomain	422..478	CDD:459649	30/55 (55%)
EMX2	NP_004089.1	Homeodomain	155..211	CDD:459649	30/56 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..252		3/6 (50%)