Protein Alignment Dr and EMX1

DIOPT Version :9

• Sequence 1: NP_477324.1
• Gene: Dr / 45285
• FlyBaseID: FBgn0000492
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 233
• Identity: 76/233 - (32%)
• Similarity: 96/233 - (41%)
• Gaps: 74/233 - (31%)

  Fly   305 IEDMNADDSPRSTPDGLDGSGKSLESPHGPPPGSHMQSTILSPAALASGHVPIRPT------PFS 363
            ||.:.|.|.  .|..|..|.|          .|||:       .|.|:...|:|||      |.:
Human    45 IESLVAKDG--GTGGGTGGGG----------AGSHL-------LAAAASEEPLRPTALNYPHPSA 90

  Fly   364 A---------LAAAAVAWTGMGGG--VPWPGTRQMP-------------PFGPPGMFPGA----- 399
            |         .||||.|...:.||  :.:|.....|             |..||..|.||
Human    91 AEAAFVSGFPAAAAAGAGRSLYGGPELVFPEAMNHPALTVHPAHQLGASPLQPPHSFFGAQHRDP 155

  Fly   400 -------------GFGGDANEPPRIKCNLRKHKP-NRKP---RTPFTTQQLLSLEKKFREKQYLS 447
                         |....|::.|  :..|..|.| .|||   ||.|:..|||.||:.|.:..|:.
Human   156 LHFYPWVLRNRFFGHRFQASDVP--QDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVV 218

  Fly   448 IAERAEFSSSLRLTETQVKIWFQNRRAKAKRLQEAEIE 485
            .|||.:.:.||.|:|||||:||||||.|.|| |:.|.|
Human   219 GAERKQLAGSLSLSETQVKVWFQNRRTKYKR-QKLEEE 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dr	NP_477324.1	Homeobox	424..477	CDD:278475	29/55 (53%)
EMX1	NP_004088.2	COG5576	140..>251	CDD:227863	45/113 (40%)
		Homeobox	196..248	CDD:278475	28/51 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..257		24/41 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810