DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dr and DLX3

DIOPT Version :9

Sequence 1:	NP_477324.1	Gene:	Dr / 45285	FlyBaseID:	FBgn0000492	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_005211.1	Gene:	DLX3 / 1747	HGNCID:	2916	Length:	287	Species:	Homo sapiens

Alignment Length:	114	Identity:	45/114 - (39%)
Similarity:	68/114 - (59%)	Gaps:	11/114 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   407 EPPRIKCNLRKHKPN--RKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWF 469
            |.|..:..:...||.  |||||.:::.||.:|:::|::.|||::.||||.::.|.||:|||||||
Human   113 EEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWF 177

  Fly   470 QNRRAKAKRLQ---EAEIE-----KIKMAALGRGAPGAQWAMAGYFHPS 510
            ||||:|.|:|.   |..:|     ...||.....:| |.|..:.:..|:
Human   178 QNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSP-ALWDTSSHSTPA 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dr	NP_477324.1	Homeobox	424..477	CDD:278475	29/52 (56%)
DLX3	NP_005211.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	20..39
		DLL_N	27..107	CDD:403572
		COG5576	<109..232	CDD:227863	45/114 (39%)
		homeobox	129..188		32/58 (55%)
		Homeobox	132..186	CDD:395001	29/53 (55%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	195..287		7/32 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810