Protein Alignment Dr and Hoxa2

DIOPT Version :10

• Sequence 1: NP_477324.1
• Gene: Dr / 45285
• FlyBaseID: FBgn0000492
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_034581.1
• Gene: Hoxa2 / 15399
• MGIID: 96174
• Length: 372
• Species: Mus musculus
• Alignment Length: 265
• Identity: 69/265 - (26%)
• Similarity: 94/265 - (35%)
• Gaps: 89/265 - (33%)

  Fly   223 LRQQQQQADARANSPPAS----TSSTPSSTPLGSALGSQGNVASTPAKNERHSPLGSHTDSELEY 283
            :..|...|:...:.||.:    :||..:||...|.|.......:.|:.|.     |||
Mouse    12 INSQPSLAECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNP-----GSH------- 64

  Fly   284 DEEMLQDHEADHDEEEDSIVDIEDMNADDSPRSTPDGLDGS---GKSLESPHGP--PPGSHMQST 343
                 ..|.|               .....|:|:|.|..||   ..:|:.|..|  ......:.|
Mouse    65 -----PRHGA---------------GVGGRPKSSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKT 109

  Fly   344 ILSPAALASGHVPIRPTPFSALAAAAVAWTGMGGGVPWPGTRQMPPFGPPGMFPGAGFGGDANEP 408
            .|.|||.::|     |.......:..:| .|.|||
Mouse   110 ALPPAAASTG-----PACLGHKESLEIA-DGSGGG------------------------------ 138

  Fly   409 PRIKCNLRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWFQNRR 473
                        :|:.||.:|..|||.|||:|...:||....|.|.::.|.|||.|||:||||||
Mouse   139 ------------SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRR 191

  Fly   474 AKAKR 478
            .|.||
Mouse   192 MKHKR 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dr	NP_477324.1	Homeodomain	422..478	CDD:459649	29/55 (53%)
Hoxa2	NP_034581.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..95		14/78 (18%)
		Antp-type hexapeptide	96..101		1/4 (25%)
		Homeodomain	140..196	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..225		2/3 (67%)