DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dr and Dlx5

DIOPT Version :9

Sequence 1:	NP_477324.1	Gene:	Dr / 45285	FlyBaseID:	FBgn0000492	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_034186.2	Gene:	Dlx5 / 13395	MGIID:	101926	Length:	289	Species:	Mus musculus

Alignment Length:	171	Identity:	60/171 - (35%)
Similarity:	88/171 - (51%)	Gaps:	20/171 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   327 SLESPHGPPPGSHMQSTILSPAALASGHVPIRPTPFS---ALAAAAVAWTGMGGGVPWPGTRQMP 388
            |.||| ..|..|...|...|||. |:.|....||..|   ||......:.|:.|.......:...
Mouse    31 SQESP-TLPESSATDSDYYSPAG-AAPHGYCSPTSASYGKALNPYQYQYHGVNGSAAGYPAKAYA 93

  Fly   389 PFGPPGMFPGAGFGGDAN-------EP------PRIKCNLRKHKPNRKPRTPFTTQQLLSLEKKF 440
            .:|...  |...:||..|       :|      |.::....|.|..|||||.:::.||.:|:::|
Mouse    94 DYGYAS--PYHQYGGAYNRVPSATSQPEKEVAEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRF 156

  Fly   441 REKQYLSIAERAEFSSSLRLTETQVKIWFQNRRAKAKRLQE 481
            ::.|||::.||||.::||.||:|||||||||:|:|.|::.:
Mouse   157 QKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKKIMK 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dr	NP_477324.1	Homeobox	424..477	CDD:278475	29/52 (56%)
Dlx5	NP_034186.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49		7/18 (39%)
		DLL_N	32..118	CDD:403572	23/89 (26%)
		Homeobox	140..194	CDD:395001	29/53 (55%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	198..253		60/171 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	270..289
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810