Protein Alignment Dr and Dlx2

DIOPT Version :10

• Sequence 1: NP_477324.1
• Gene: Dr / 45285
• FlyBaseID: FBgn0000492
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_034184.1
• Gene: Dlx2 / 13392
• MGIID: 94902
• Length: 332
• Species: Mus musculus
• Alignment Length: 298
• Identity: 86/298 - (28%)
• Similarity: 118/298 - (39%)
• Gaps: 89/298 - (29%)

  Fly   240 STSSTPSST-------PLGSALGSQGNVASTPAKNERHSPLGSHTDSELEYDEEMLQDHEADHDE 297
            ||..|.|||       |.|:..|..||..|:.:.:..|.|..|.|
Mouse    14 STQITASSTYHQHQQPPSGAGAGPGGNSNSSSSNSSLHKPQESPT-------------------- 58

  Fly   298 EEDSIVDIEDMNADDSPRST----PDGLDGSGKSLESPHGPPPGSHMQSTILSPAALASGHVPIR 358
                   :....|.||...|    |.|..|.|.|        |.:||.|....    |||   :.
Mouse    59 -------LPVSTATDSSYYTNQQHPAGGGGGGAS--------PYAHMGSYQYH----ASG---LN 101

  Fly   359 PTPFSALAAAAVAWTGMGGGVPWPGTRQMPPFGPPGMFPGAGFGGDANEP------PRIKCNLRK 417
            ...:||.::..:.:|.........||...|.               .|||      |.|:....|
Mouse   102 NVSYSAKSSYDLGYTAAYTSYAPYGTSSSPV---------------NNEPDKEDLEPEIRIVNGK 151

  Fly   418 HKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWFQNRRAKAKRL-QE 481
            .|..|||||.:::.||.:|:::|::.|||::.||||.::||.||:|||||||||||:|.|:: :.
Mouse   152 PKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWKS 216

  Fly   482 AEIEKIKMAALGRGAP--------------GAQWAMAG 505
            .||...:........|              ||...|||
Mouse   217 GEIPTEQHPGASASPPCASPPVSAPASWDFGAPQRMAG 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dr	NP_477324.1	Homeodomain	422..478	CDD:459649	32/55 (58%)
Dlx2	NP_034184.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..83		20/90 (22%)
		DLL_N	54..135	CDD:463567	24/137 (18%)
		Homeodomain	156..212	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..272		7/36 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	304..332