DRSC/TRiP Functional Genomics Resources

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Protein Alignment dib and cyp11c1

DIOPT Version :10

Sequence 1:NP_524810.2 Gene:dib / 45282 FlyBaseID:FBgn0000449 Length:489 Species:Drosophila melanogaster
Sequence 2:XP_017206857.1 Gene:cyp11c1 / 791124 ZFINID:ZDB-GENE-070828-1 Length:701 Species:Danio rerio


Alignment Length:522 Identity:144/522 - (27%)
Similarity:224/522 - (42%) Gaps:70/522 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 SCTSRQCTFAKPYQAI----------PGPRGPFGMGNLYNYLPGIGSYSWL------------RL 51
            ||....|  |:|:..:          ...|.. |...|:..:|..||..|:            |:
Zfish   187 SCAGSVC--ARPHLCVRASVCVRPLHQSSRSA-GAARLFQEIPDTGSNGWMNLLRFWRDGRFSRM 248

  Fly    52 HQAGQDKYEKYGAIVRETIVPGQDIVWLYDPKDIA-LLLNERDCPQRRSHLALAQYRKSRPDVYK 115
            |:..::.:.:.|.|.||.: ..|..|.:..|.|.. |..:|...|:|.:....|.:|::|   ..
Zfish   249 HKHMEESFRRLGPIYREHL-GSQSSVNIMLPMDTGELFRSEGLHPRRMTLQPWATHRETR---RH 309

  Fly   116 TTGLLPTNGPEWWRIRAQVQKELSAPKSVRNFVRQVDGVTKEFIR----------FLQESRNGGA 170
            :.|:...||.||...|..:.:|:....||..|:..:|.|.::|.|          |.:..::...
Zfish   310 SKGVFLKNGTEWRADRLLLNREVMVSSSVHRFLPLLDEVAQDFCRSLRRRVQADGFEKAGQHTLT 374

  Fly   171 IDMLPKLTRLNLELTCLLTFGARLQSFTAQEQDPRSRSTRLMDAAE----TTNSCI-LPTDQGLQ 230
            :|..|.|.|..||.:|.:.:|.|:..|::   .|...|.|.:.|.|    ||...: ||....|:
Zfish   375 LDPSPDLFRFALEASCHVLYGERIGLFSS---CPSDESERFISAVERMLATTPPLLYLPPRLLLR 436

  Fly   231 ----LWRFLETPSFRKLSQAQ-----SYMESVALELVEENVRNGSVGSSLISAYVKNPELDRSDV 286
                ||....|......|.|:     ||....|......:.....|...|:.|...:.||.|:::
Zfish   437 LRASLWTTHATAWDDIFSHAEQRIQRSYQRLQARPSAAPDCSFPGVLGKLMEAGQLSLELIRANI 501

  Fly   287 VGTAADLLLAGIDTTSYASAFLLYHIARNPEVQQKLHEEARRVLPSAKDELSMDALRT--DITYT 349
                .:|:..|:|||:....|.|:.:||||:||    |..|..:.|:..:.|.|.|:.  .....
Zfish   502 ----TELMAGGVDTTAVPLQFALFELARNPDVQ----ECVRAQVLSSWQQASGDPLKALQGAPLL 558

  Fly   350 RAVLKESLRLNPIAVGVGRILNQDAIFSGYFVPKGTTVVTQNMVACRLEQHFQDPLRFQPDRWLQ 414
            :..:||:|||.|:.:.|.|...:|.:...|.||.||.|........|..:.|..|..|.|.||..
Zfish   559 KGTIKETLRLYPVGITVQRYPVRDIVLQNYHVPAGTLVQVCLYPLGRSAEVFSRPECFDPSRWSA 623

  Fly   415 HRSA--LNPYLVLPFGHGMRACIARRLAEQNMHILLLRLLREYELIWSGSDDEMGVKTLLINKPD 477
            ...|  ...:..|.||.|.|.|:.||:||..|.:||:.:||.::|..| |.:|:..|..||.:|:
Zfish   624 DADAGSAGGFRSLAFGFGSRQCVGRRIAENEMQLLLMHILRTFKLTVS-STEELSTKYTLILQPE 687

  Fly   478 AP 479
            .|
Zfish   688 CP 689

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dibNP_524810.2 CYP24A1-like 59..480 CDD:410677 130/450 (29%)
cyp11c1XP_017206857.1 Synaphin 1..125 CDD:461755
Complexin_NTD_CPLX_III_IV 46..87 CDD:439283
cytochrome_P450 256..694 CDD:477761 130/450 (29%)
Blue background indicates that the domain is not in the aligned region.

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