Protein Alignment dib and cyp27a1.3

DIOPT Version :10

• Sequence 1: NP_524810.2
• Gene: dib / 45282
• FlyBaseID: FBgn0000449
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: XP_002934001.3
• Gene: cyp27a1.3 / 594905
• XenbaseID: XB-GENE-18386061
• Length: 518
• Species: Xenopus tropicalis
• Alignment Length: 519
• Identity: 126/519 - (24%)
• Similarity: 215/519 - (41%)
• Gaps: 106/519 - (20%)

  Fly    19 KPYQAIPGPRGPFGMGNLY-----NYLPGIGSYSWLRLHQAGQDKYEKYGAIVRETIVPGQDIVW 78
            |....:||| .|..:  ||     .||        .|.|:        ...|.::|..|    :|
 Frog    45 KTLDDLPGP-SPLKL--LYWIFLRGYL--------FRTHE--------LQVIFKKTYGP----MW 86

  Fly    79 LYDPKDIA------------LLLNERDCPQRRSHLALAQYRKSRPDVYKTTGLLPTNGPEWWRIR 131
            ....:..|            ||..|...|.|.....:.::|..|...|   |.:...|.:|.|||
 Frog    87 KMSDRQHAMVTVASPDLLESLLRKEGKYPTRADMFIMREHRDLRGHSY---GPVTEEGHQWHRIR 148

  Fly   132 AQVQKELSAPKSVRNFVRQVDGVTKEFIRFLQE----SRNGGAIDMLPKLT-RLNLELTCLLTFG 191
            ..:.:.:..|:....:...::.|..:.:..::|    |.:|..::.:.:|. :...|..|.:.|.
 Frog   149 TILNQRMLKPRETVVYAGSMNEVVSDLLLKIKELTAQSSSGTQVNGVAELMYKFAFESICTVLFE 213

  Fly   192 ARLQSFTAQEQDPRSRSTRLMDAAETTNSCILPTDQ------GLQL-----------WRFLETPS 239
            .||...                     |..|||..|      |:.|           |.....|.
 Frog   214 TRLGCL---------------------NKEILPETQKFIDSIGIMLEHLTMLTRLPQWTKGILPY 257

  Fly   240 FRKLSQAQSYMESVALELVEENV--------RNGSVGSSLISAYVKNPELDRSDVVGTAADLLLA 296
            :.:..:|...:.....:|:::.:        |...|....::..:.:.:|...:|.|:..:||.|
 Frog   258 WGRYIEAWDTIFDFGKKLIDKKMEDIEGRLKRGEEVEGEYLTYLLSSGKLSMEEVYGSVVELLQA 322

  Fly   297 GIDTTSYASAFLLYHIARNPEVQQKLHEEARRVLPSAKDELSMDALRTDITYTRAVLKESLRLNP 361
            |:||||....:.||.::||||:|..|::|..||:|......|....|..:  .:||:||:|||.|
 Frog   323 GVDTTSNTLTWALYQLSRNPEIQNNLYQEVIRVIPGETIPDSEAIARMPL--LKAVIKETLRLFP 385

  Fly   362 IAVGVGRILNQ-DAIFSGYFVPKGTTVVTQNMVACRLEQHFQDPLRFQPDRWLQHRSAL-NPYLV 424
            :.....|::|: :.....|..|..|..:..:....|.|..|.:..||.|:|||:..... :|:..
 Frog   386 VVPENARMINEKEVTIKDYVFPVKTQFILGHYAISRDETTFPEADRFLPERWLRDSGMKHHPFGS 450

  Fly   425 LPFGHGMRACIARRLAEQNMHILLLRLLREYELIWSGSDDEMGVK---TLLINKPDAPVLIDLR 485
            :|||:|:|||:.||:||..||:.|.|:::.:::|......|:|.|   .|:.|:|     ::||
 Frog   451 IPFGYGVRACVGRRIAELEMHLALSRIIKMFQVIPDPDLGEVGAKNRAVLVANRP-----VNLR 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dib	NP_524810.2	CYP24A1-like	59..480	CDD:410677	113/467 (24%)
cyp27a1.3	XP_002934001.3	cytochrome_P450	79..508	CDD:477761	112/463 (24%)