Protein Alignment dib and cyp27a2

DIOPT Version :10

• Sequence 1: NP_524810.2
• Gene: dib / 45282
• FlyBaseID: FBgn0000449
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: XP_686522.4
• Gene: cyp27a2 / 558239
• ZFINID: ZDB-GENE-120215-110
• Length: 573
• Species: Danio rerio
• Alignment Length: 503
• Identity: 139/503 - (27%)
• Similarity: 224/503 - (44%)
• Gaps: 82/503 - (16%)

  Fly    24 IPGPRGPFGMGNLYNYLPGIGSYSWL-------RLHQAGQDKYEKYGAIVRETIVPGQDIVWLYD 81
            :|||       ||..      :..||       :.|....:....||.|.|....| .|::.:..
Zfish   107 LPGP-------NLAT------TVYWLFVKGYADKSHAMQVEHKRLYGPIWRSRFGP-FDVINVAG 157

  Fly    82 PKDIALLLNER-------DCPQRRSHLALAQYRKSRPDVYKTTGLLPTNGPEWWRIRAQVQKELS 139
            ...||.::.:.       |.|..|      :||..|...|   |:....||||:|||:.:..::.
Zfish   158 ADLIAQVIRQEGRYPVRTDLPHWR------EYRDMRGQAY---GIHVDTGPEWYRIRSALNPKML 213

  Fly   140 APKSVRNFVRQVDGVTKEFIRFLQ--ESRNGGAI---DMLPKLTRLNLELTCLLTFGARLQSFTA 199
            ..|.|..:...:..|..:.::.|:  ..|:...|   |:..:|.:...|....:.|..||...
Zfish   214 KLKEVTAYAPIIHEVVSDLLQRLELLRLRSPDQITVSDLASELYKFGFEGISSILFETRLGCL-- 276

  Fly   200 QEQDPR------SRSTRLMDAAETTNSCILPTDQGLQLWRFLETPSFRKLSQAQSYMESVALELV 258
            ||:.|.      |....::..:||.  ...|.      |.....|.:::..||...:..||..|:
Zfish   277 QEEIPTDTLRFISAVNEMLALSETV--LFFPR------WTRHIFPFWKRFVQAWDELYDVARHLI 333

  Fly   259 EENV--------RNGSVGSSLISAYVKNPELDRSDVVGTAADLLLAGIDTTSYASAFLLYHIARN 315
            ::.|        |...|....::..:.:.:|...:|..:..:|||.|:||||...::.|||:|||
Zfish   334 DKKVNEIRDQVARGEEVEGMYLTYLLSSNKLSLGEVYISLTELLLGGVDTTSNTLSWTLYHLARN 398

  Fly   316 PEVQQKLHEEARRVLPSAK----DELSMDALRTDITYTRAVLKESLRLNPIAVGVGRI-LNQDAI 375
            ||:|::||.|...|.|:.|    |:|      |.:.|.:||:||.||:.|:..|.||: ::.|.:
Zfish   399 PEIQKRLHNEIVSVCPNKKVPNTDDL------TKMPYMKAVIKEILRMYPVVPGNGRLTVDSDIV 457

  Fly   376 FSGYFVPKGTTVVTQNMVACRLEQHFQDPLRFQPDRWLQ---HRSALNPYLVLPFGHGMRACIAR 437
            ...|:.||.|.....:......|.:|.|..||.|:||::   .||..:||..:|||.|:|||:.:
Zfish   458 VDNYWFPKKTQFHLCHYAVSHDENNFPDAERFVPERWIRDSPSRSQHHPYSSVPFGVGVRACVGK 522

  Fly   438 RLAEQNMHILLLRLLREYELIWSGSDDEMGVKTLLINKPDAPVLIDLR 485
            |:||..|:..|.||:::||:........:..||..:..|..|  |||:
Zfish   523 RVAELEMYFALSRLMQQYEVRTKAGSPSIQPKTRTLLIPSQP--IDLQ 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dib	NP_524810.2	CYP24A1-like	59..480	CDD:410677	127/454 (28%)
cyp27a2	XP_686522.4	cytochrome_P450	136..567	CDD:477761	129/458 (28%)