Protein Alignment dib and Cyp11b1

DIOPT Version :10

• Sequence 1: NP_524810.2
• Gene: dib / 45282
• FlyBaseID: FBgn0000449
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_036669.3
• Gene: Cyp11b1 / 500892
• RGDID: 2453
• Length: 499
• Species: Rattus norvegicus
• Alignment Length: 503
• Identity: 136/503 - (27%)
• Similarity: 221/503 - (43%)
• Gaps: 85/503 - (16%)

  Fly    19 KPYQAIPGPRGPFGMGNLYNYLPGIGSYS---WLR----LHQAGQDK--------YEKYGAIVRE 68
            ||::|||                   .||   ||:    |.:.||:.        :::.|.|.|.
  Rat    36 KPFEAIP-------------------QYSRNKWLKMIQILREQGQENLHLEMHQAFQELGPIFRH 81

  Fly    69 TIVPGQDIVWLYDPKDIALLLN-ERDCPQRR------SHLALAQYRKSRPDVYKTTGLLPTNGPE 126
            : ..|..||.:..|:|...|.. |...|.|.      :|..|...|:         |:...||.:
  Rat    82 S-AGGAQIVSVMLPEDAEKLHQVESILPHRMPLEPWVAHRELRGLRR---------GVFLLNGAD 136

  Fly   127 WWRIRAQVQKELSAPKSVRNFVRQVDGVTKEFI-----RFLQESRNGGAIDMLPKLTRLNLELTC 186
            |...|.|:...:.:||::::||..||.|.::|:     |.|:......:|::...:....:|.:.
  Rat   137 WRFNRLQLNPNMLSPKAIQSFVPFVDVVARDFVENLKKRMLENVHGSMSINIQSNMFNYTMEASH 201

  Fly   187 LLTFGARLQSFTAQEQDPRSRS-TRLMDA--AETTNSCILPTDQGLQLWRFLETPSFRK------ 242
            .:..|.|| ..|..:..|.|.: |..:.:  ..||....||.    .|.|:..|..:::
  Rat   202 FVISGERL-GLTGHDLKPESVTFTHALHSMFKSTTQLMFLPK----SLTRWTSTRVWKEHFDSWD 261

  Fly   243 -LSQ-AQSYMESVALELVEENVRNGSVGSSLISAYVKNPELDRSDVVGTAADLLLAGIDTTSYAS 305
             :|: ....:::|..||.|...::.||    ||..|....|....:...:.:|:...:|||:.:.
  Rat   262 IISEYVTKCIKNVYRELAEGRQQSWSV----ISEMVAQSTLSMDAIHANSMELIAGSVDTTAISL 322

  Fly   306 AFLLYHIARNPEVQQKLHEEARRVLPS--AKDELSMDALRTDITYTRAVLKESLRLNPIAVGVGR 368
            ...|:.:||||:|||.|.:|:.....|  |..:.:|    :|:...||.|||:|||.|:...|.|
  Rat   323 VMTLFELARNPDVQQALRQESLAAEASIVANPQKAM----SDLPLLRAALKETLRLYPVGSFVER 383

  Fly   369 ILNQDAIFSGYFVPKGTTVVTQNMVACRLEQHFQDPLRFQPDRWLQHRSALNPYLVLPFGHGMRA 433
            |::.|.:...|.||.||.|:.......|....|..|.|:.|.|||:.:.:   :..|.||.|||.
  Rat   384 IVHSDLVLQNYHVPAGTFVIIYLYSMGRNPAVFPRPERYMPQRWLERKRS---FQHLAFGFGMRQ 445

  Fly   434 CIARRLAEQNMHILLLRLLREYELIWSGSDDEMGVKTLLINKPDAPVL 481
            |:.|||||..|.:||..:|:.:::.....:|...|...|:....:|.|
  Rat   446 CLGRRLAEVEMLLLLHHMLKTFQVETLRQEDMQMVFRFLLMPSSSPFL 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dib	NP_524810.2	CYP24A1-like	59..480	CDD:410677	122/445 (27%)
Cyp11b1	NP_036669.3	cytochrome_P450	72..495	CDD:477761	124/448 (28%)