Protein Alignment dib and cyp27a1.1

DIOPT Version :10

• Sequence 1: NP_524810.2
• Gene: dib / 45282
• FlyBaseID: FBgn0000449
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: XP_002663445.1
• Gene: cyp27a1.1 / 402831
• ZFINID: ZDB-GENE-081104-519
• Length: 524
• Species: Danio rerio
• Alignment Length: 481
• Identity: 130/481 - (27%)
• Similarity: 231/481 - (48%)
• Gaps: 64/481 - (13%)

  Fly    40 LPGIGSYSWL----------RLHQAGQDKYEK--YGAIVRETIVPGQDIVWLYDPKDI--ALLLN 90
            ||.|..::.|          |:|:.  ..|||  ||.:.:..:...|.:.  .:..|:  .||..
Zfish    56 LPEIKIFTMLYRLLFKGYLSRMHEL--QLYEKQLYGPLYKINVGNFQSVA--LNSVDLLEELLRK 116

  Fly    91 ERDCPQRRSHLALAQYRKSRPDVYKTTGLLPTNGPEWWRIRAQVQKELSAPKSVRNFVRQVDGVT 155
            :...|.|.......:||..:...|   |.....|.:|:::||.:.|.:..||....:...|:.|.
Zfish   117 DEKFPSRGDMTLWTEYRDMKGIGY---GPFTEEGEKWYKLRAVLNKRMLHPKDSVQYGDVVNAVI 178

  Fly   156 KEFIR---FLQESRNGGAIDMLPKLT----RLNLELTCLLTFGARLQSFTAQEQDPRSRSTRLMD 213
            .:||:   :|:|....|  |::..||    |.:||....:.|..|:...   |::..:.:...::
Zfish   179 TDFIKRIYYLREMSPTG--DLVSNLTNELYRFSLEGISSILFETRIGCL---EKEIPAETQHFIN 238

  Fly   214 AAETTNSCILP-------TDQGLQLW-RFLETPSFRKLSQAQSYMESVALELVEENV-RNGSVGS 269
            :.....:..:|       |...|..| |::  ..:..:.:....|..:.:|.:::.| .|..|..
Zfish   239 SIAQMLTYSMPVVFMPNWTRNYLPFWQRYI--GGWDGIFKFAGKMIDMKMEALQKRVDANQEVAG 301

  Fly   270 SLISAYVKNPELDRSDVVGTAADLLLAGIDTTSYASAFLLYHIARNPEVQQKLHEEARRVL---- 330
            ..::..:.|.::...||.|:.::|||||:||||....|.|||::::||.|..|::|...||
Zfish   302 EYLTYLLSNGKMSSKDVYGSVSELLLAGVDTTSNTMLFALYHLSKDPETQDILYQEVTNVLKDDR 366

  Fly   331 -PSAKDELSMDALRTDITYTRAVLKESLRLNPIAVGVGRIL-NQDAIFSGYFVPKGTTVVTQNMV 393
             |:|::..:|       :|.:||:||:|||.|:.....|:: ..:.:..|:..||.||....:..
Zfish   367 IPTAQEVNTM-------SYLKAVIKETLRLYPVVPMNARLIAENEVVIGGHLFPKNTTFTLCHYA 424

  Fly   394 ACRLEQHFQDPLRFQPDRWLQH-RSALNPYLVLPFGHGMRACIARRLAEQNMHILLLRLLREYEL 457
            ..|.|:.|.:|.:|:|:|||:. |:..||:..:|||.|:|.|:.||:||..|::.|.||::.:|:
Zfish   425 ISRDEKVFPEPQKFKPERWLRDGRTRPNPFGSIPFGFGVRGCVGRRIAELEMYLALARLIKLFEI 489

  Fly   458 IWSGSDDEMG-VKTL--LINKPDAPV 480
               ..|..:| |::|  .:..||..|
Zfish   490 ---RPDPTVGEVRSLNRTVLAPDRKV 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dib	NP_524810.2	CYP24A1-like	59..480	CDD:410677	123/450 (27%)
cyp27a1.1	XP_002663445.1	cytochrome_P450	85..514	CDD:477761	122/450 (27%)