DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dib and Cyp28a5

DIOPT Version :9

Sequence 1:	NP_524810.2	Gene:	dib / 45282	FlyBaseID:	FBgn0000449	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	NP_609694.1	Gene:	Cyp28a5 / 34817	FlyBaseID:	FBgn0028940	Length:	505	Species:	Drosophila melanogaster

Alignment Length:	509	Identity:	113/509 - (22%)
Similarity:	188/509 - (36%)	Gaps:	138/509 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 QAIPGPRGPFGMGNLYNY--LPGIGSYSWLRLHQAGQDKYEKYG--------------AIVRETI 70
            :.:|||:.....||..|.  :.....|....:::..::||:..|              |:.|...
  Fly    30 RGVPGPKPKLLCGNYPNMFTMKRHAIYDLDDIYRQYKNKYDAVGIFGSRSPQLLVINPALARRVF 94

  Fly    71 VPGQDIVWLYDPKDIALLLNERDCPQRRSHLALAQYRKSRPDVYKTTGLLPTN-----GPEWWRI 130
            |  .:....:| .:||..::|                       ||..:...|     |.:|...
  Fly    95 V--SNFKNFHD-NEIAKNIDE-----------------------KTDFIFANNPFSLTGEKWKTR 133

  Fly   131 RAQVQKELSAPKSVRNFVRQVDGVTKEFIRFLQE---------SRNGGAIDMLPKLTRLNLELT- 185
            ||.|...|:..:     ::.|..||.:..:.|.|         |::|  ||..........|:.
  Fly   134 RADVTPGLTMGR-----IKTVYPVTNKVCQKLTEWVEKQLRLGSKDG--IDAKHMSLCFTTEMVT 191

  Fly   186 -CLLTFGARLQSFTAQEQDPRSRSTRLMDAAETTNSCILPTDQGLQLWR----FLETPSFRKLSQ 245
             |:|..||  :||:.:.....|:...|.:                |.|.    |:.|.||..||.
  Fly   192 DCVLGLGA--ESFSDKPTPIMSKINDLFN----------------QPWTFVLFFILTSSFPSLSH 238

  Fly   246 AQSYMESVALELVEENVRN------GSVGSSLISAYVKNPELDRSD------------------V 286
            .      :.|..|..:|..      ||...:..:......:.:|||                  :
  Fly   239 L------IKLRFVPVDVERFFVDLMGSAVETRRAQLAAGKQFERSDFLDYILQLGEKRNLDNRQL 297

  Fly   287 VGTAADLLLAGIDTTSYASAFLLYHIARNPEVQQKLHEEARRVLPS---AKDELSMDALRTDITY 348
            :..:...||.|.:||:...|.:|.::.||.|.|..|.||.|..|..   |.::||      |:.|
  Fly   298 LAYSMTFLLDGFETTATVLAHILLNLGRNKEAQNLLREEIRSHLQDGTIAFEKLS------DLPY 356

  Fly   349 TRAVLKESLRL-------NPIAVGVGRILNQDAIFSGYFVPKGTTVVTQNMVACRLEQHFQDPLR 406
            ..|.::|::||       |.:......|.|::.  ..:.|.||||||..:......|:.|.:|..
  Fly   357 LDACVQETIRLFPPGFMSNKLCTESIEIPNKEG--PNFVVEKGTTVVVPHYCFMLDEEFFPNPQS 419

  Fly   407 FQPDRWLQHRSA---LNPYLVLPFGHGMRACIARRLAEQNMHILLLRLLREYEL 457
            |||:|:|:..:|   ....:.:.||.|.|.||..|.|...:...::.|:.::.:
  Fly   420 FQPERFLEPDAAKTFRERGVFMGFGDGPRVCIGMRFATVQIKAAIVELISKFNV 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dib	NP_524810.2	p450	25..446	CDD:299894	112/493 (23%)
Cyp28a5	NP_609694.1	p450	33..500	CDD:299894	113/506 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910