Protein Alignment dib and Cyp11a1

DIOPT Version :10

• Sequence 1: NP_524810.2
• Gene: dib / 45282
• FlyBaseID: FBgn0000449
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_058982.1
• Gene: Cyp11a1 / 29680
• RGDID: 69325
• Length: 526
• Species: Rattus norvegicus
• Alignment Length: 492
• Identity: 143/492 - (29%)
• Similarity: 236/492 - (47%)
• Gaps: 51/492 - (10%)

  Fly    19 KPYQAIPGPRGPFGMGNLYNYLPGIGSYSWLRLHQAGQDKYEKYGAIVRETIVPGQDIVWLYDPK 83
            :.:..||.| |..|..|||::|...|::   |:|......::|||.|.||.: ...:.|::.|||
  Rat    44 RSFNEIPSP-GDNGWINLYHFLRENGTH---RIHYHHMQNFQKYGPIYREKL-GNMESVYILDPK 103

  Fly    84 DIALLLN-ERDCPQR---RSHLALAQYRKSRPDVYKTTGLLPTNGPEWWRIRAQVQKELSAPKSV 144
            |.|.|.: |...|:|   ...:|..||.: ||     .|:|..:...|.:.|..:.:|:.||.|:
  Rat   104 DAATLFSCEGPNPERYLVPPWVAYHQYYQ-RP-----IGVLFKSSDAWRKDRIVLNQEVMAPDSI 162

  Fly   145 RNFVRQVDGVTKEFIRFLQ---ESRNGGAI--DMLPKLTRLNLELTCLLTFGARLQSFTAQEQDP 204
            :|||..::||.::||:.|.   :.:|.|..  |:...|.|...|....:.||.|| ....:..||
  Rat   163 KNFVPLLEGVAQDFIKVLHRRIKQQNSGKFSGDISDDLFRFAFESITSVVFGERL-GMLEEIVDP 226

  Fly   205 RSRSTRLMDAA----ETTNSCI-LPTDQGLQLWRFLETPSFRK--------LSQAQSYMESVALE 256
            .|:  |.:||.    .|:...: :|.|    |:|...|.:::.        .|:|..|.::...:
  Rat   227 ESQ--RFIDAVYQMFHTSVPMLNMPPD----LFRLFRTKTWKDHAAAWDVIFSKADEYTQNFYWD 285

  Fly   257 LVEENVRNGSVGSSLISAYVKNPELDRSDVVGTAADLLLAGIDTTSYASAFLLYHIARNPEVQQK 321
            |.::  |:.|....::.:.:...:|...::.....::|..|:||||....:.||.:|.|.:||:.
  Rat   286 LRQK--RDFSKYPGVLYSLLGGNKLPFKNIQANITEMLAGGVDTTSMTLQWNLYEMAHNLKVQEM 348

  Fly   322 LHEE---ARRVLPSAKDELSMDALRTDITYTRAVLKESLRLNPIAVGVGRILNQDAIFSGYFVPK 383
            |..|   |||  .:..|...|..|   :...:|.:||:|||:||:|.:.|.:..|.:...|.:|.
  Rat   349 LRAEVLAARR--QAQGDMAKMVQL---VPLLKASIKETLRLHPISVTLQRYIVNDLVLRNYKIPA 408

  Fly   384 GTTVVTQNMVACRLEQHFQDPLRFQPDRWLQHRSALNPYLVLPFGHGMRACIARRLAEQNMHILL 448
            .|.|...:....|....|.:|.:|.|.|||:.......:..|.||.|:|.|:.||:||..|.|.|
  Rat   409 KTLVQVASYAMGRESSFFPNPNKFDPTRWLEKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTIFL 473

  Fly   449 LRLLREYELIWSGSDDEMGVKTLLINKPDAPVLIDLR 485
            :.:|..:. |...|..::|.|..||..|:.|:..:.:
  Rat   474 INVLENFR-IEVQSIRDVGTKFNLILMPEKPIFFNFQ 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dib	NP_524810.2	CYP24A1-like	59..480	CDD:410677	130/445 (29%)
Cyp11a1	NP_058982.1	cytochrome_P450	80..505	CDD:477761	131/446 (29%)