Protein Alignment dib and Cyp11b2

DIOPT Version :10

• Sequence 1: NP_524810.2
• Gene: dib / 45282
• FlyBaseID: FBgn0000449
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_036670.2
• Gene: Cyp11b2 / 24294
• RGDID: 2454
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 539
• Identity: 146/539 - (27%)
• Similarity: 222/539 - (41%)
• Gaps: 125/539 - (23%)

  Fly     3 TKLLKISCTSRQCTFAKPYQAIPGPRGPFGMGNLYNYLPGIGSYS---WLR----LHQAGQDK-- 58
            |:.|..:.|....|. ||::|||                   .||   ||:    |.:.||:.
  Rat    23 TRALGTTATLAPKTL-KPFEAIP-------------------QYSRNKWLKMIQILREQGQENLH 67

  Fly    59 ------YEKYGAIVRETIVPGQDIVWLYDPKDIALLLNERDCPQRRSHL----ALAQYRKSRPDV 113
                  :::.|.|.|.: ..|..||.:..|:|...|........||.||    |..:.|..|..|
  Rat    68 LEMHQAFQELGPIFRHS-AGGAQIVSVMLPEDAEKLHQVESILPRRMHLEPWVAHRELRGLRRGV 131

  Fly   114 YKTTGLLPTNGPEWWRIRAQVQKELSAPKSVRNFVRQVDGVTKEFIRFL-----QESRNGGAIDM 173
            :    ||  ||.:|...|.::...:.:||:|:|||..||.|.::|:..|     |.:|....:|:
  Rat   132 F----LL--NGADWRFNRLKLNPNVLSPKAVQNFVPMVDEVARDFLEALKKKVRQNARGSLTMDV 190

  Fly   174 LPKLTRLNLELTCLLTFGARL----------------------QSFTAQEQDPRS----RSTRL- 211
            ...|....:|.:....||.||                      :|.|.....|||    .|||:
  Rat   191 QQSLFNYTIEASNFALFGERLGLLGHDLNPGSLKFIHALHSMFKSTTQLLFLPRSLTRWTSTRVW 255

  Fly   212 ---MDA----AETTNSCILPTDQGLQLWRFLETPSFRKLSQAQSYMESVALELVEENVRNGSVGS 269
               .||    :|..|.||....|.|            :|..:|:|                   |
  Rat   256 KEHFDAWDVISEYANRCIWKVHQEL------------RLGSSQTY-------------------S 289

  Fly   270 SLISAYVKNPELDRSDVVGTAADLLLAGIDTTSYASAFLLYHIARNPEVQQKLHEE--ARRVLPS 332
            .:::|.:....|....:...:.:|....:|||:......|:.:||||:|||.|.:|  |.....:
  Rat   290 GIVAALITQGALPLDAIKANSMELTAGSVDTTAIPLVMTLFELARNPDVQQALRQETLAAEASIA 354

  Fly   333 AKDELSMDALRTDITYTRAVLKESLRLNPIAVGVGRILNQDAIFSGYFVPKGTTVVTQNMVACRL 397
            |..:.:|    :|:...||.|||:|||.|:...:.||||.|.:...|.||.||.|:.......|.
  Rat   355 ANPQKAM----SDLPLLRAALKETLRLYPVGGFLERILNSDLVLQNYHVPAGTLVLLYLYSMGRN 415

  Fly   398 EQHFQDPLRFQPDRWLQHRSALNPYLVLPFGHGMRACIARRLAEQNMHILLLRLLREYELIWSGS 462
            ...|..|.|:.|.|||:.:.:   :..|.||.|:|.|:.|||||..|.:||..:|:.:::.....
  Rat   416 PAVFPRPERYMPQRWLERKRS---FQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKTFQVETLRQ 477

  Fly   463 DDEMGVKTLLINKPDAPVL 481
            :|.......::....:|||
  Rat   478 EDVQMAYRFVLMPSSSPVL 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dib	NP_524810.2	CYP24A1-like	59..480	CDD:410677	127/465 (27%)
Cyp11b2	NP_036670.2	cytochrome_P450	74..498	CDD:477761	130/468 (28%)