DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dib and cyp-35A3

DIOPT Version :9

Sequence 1:	NP_524810.2	Gene:	dib / 45282	FlyBaseID:	FBgn0000449	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	NP_504121.1	Gene:	cyp-35A3 / 187209	WormBaseID:	WBGene00019565	Length:	494	Species:	Caenorhabditis elegans

Alignment Length:	533	Identity:	117/533 - (21%)
Similarity:	198/533 - (37%)	Gaps:	147/533 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLTKLLKISCTSRQCTFAKPYQAIP-GPRGPFG---MGNLYNYLPGIGSYSW-----------LR 50
            |...|...:|.|  ....:.||.:. .|.||..   :||    ||.|..|.|           ||
Worm     1 MFFVLFIAACLS--WLIVRQYQKVSRHPPGPISFPLIGN----LPQICYYLWSTGGIVSALDLLR 59

  Fly    51 LHQAGQDKYEKYGAIVRETIVPGQDIVWLYDPKDIALLLNERDCPQRRSHLALAQYRKSRP---- 111
                     :|||.|....:.|                     .|    ::::|.:..|..
Worm    60 ---------KKYGNIFTLWVGP---------------------VP----YVSIADFETSHEVFVK 90

  Fly   112 ---------------DVYKTTGLLPTNGPEWWRIRAQVQKELSAPKSVRNFVRQVDGVTKEFI-- 159
                           |:.|..|:..|||..|..:|.      .:.::.||.     ||.|:.:
Worm    91 NGGKYADKLHAPIMRDIRKDKGIAFTNGDHWQEMRR------FSLQTFRNM-----GVGKDIMET 144

  Fly   160 RFLQE-----------SRNGGAIDMLPKLTRLNLELTCLLTFGARLQSFTAQ---EQDPRSRSTR 210
            |.|:|           ::||..:....:...        ||.|:.:.|....   |:|.:....|
Worm   145 RILEELDARCSDIDKSAKNGVTVAQASEFFD--------LTVGSVINSILVGKRFEEDTKHVFLR 201

  Fly   211 LMDAAETTNSCILPTDQGLQLWRFLET---PSFRKLSQAQSYMES-VALELVE--ENVRNGS--V 267
            :.:..:.:...|.|.:..:.:| .|:|   ..:.|::.||...:: ||.|.::  |::::|.  :
Worm   202 IKNTIDESFKLITPFNTTVPVW-ILKTFFKDRYDKMADAQEIAKNFVAAEALKRIEDIKSGKYVI 265

  Fly   268 GSSLISAYV-----------KNPELDRSDVVGTAADLLLAGID--TTSYASAF--LLYHIARNPE 317
            ..:.:..|.           :|.:.:...:.....||.|.|.:  ||:..|.|  ||.|    ||
Worm   266 DENNLQDYTDAFLLKMQKEGENLDFNTETLKTMLVDLWLTGQETTTTTLTSGFNQLLLH----PE 326

  Fly   318 VQQKLHEEARRVLPSAKDELSMDALRTDITYTRAVLKESLR----LNPIAVGVGRILNQDAIFSG 378
            |..|..||...|..:....||:.. |:...|..|::.|..|    ||   :...::..:.....|
Worm   327 VMVKAREELMNVTENGSRSLSLTD-RSSTPYLNAMIGEIQRHASILN---LSFWKVNKEFTYIGG 387

  Fly   379 YFVPKGTTVVTQNMVACRLEQHFQDPLRFQPDRWLQHRSALNPYLVLPFGHGMRACIARRLAEQN 443
            :.|..|..|..|.......|.:|.:|..|:|:|:.|....|..  ::|||.|.|:|:...||:..
Worm   388 HPVDAGALVTAQLSALHVNETYFTNPQVFEPERYSQDEKLLQK--IIPFGVGKRSCLGESLAKAE 450

  Fly   444 MHILLLRLLREYE 456
            ::::...||..|:
Worm   451 LYLIFGNLLLRYK 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dib	NP_524810.2	p450	25..446	CDD:299894	108/497 (22%)
cyp-35A3	NP_504121.1	p450	26..466	CDD:278495	111/506 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000