Protein Alignment dib and cyp27a1

DIOPT Version :10

• Sequence 1: NP_524810.2
• Gene: dib / 45282
• FlyBaseID: FBgn0000449
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: XP_002933986.3
• Gene: cyp27a1 / 100145331
• XenbaseID: XB-GENE-984298
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 507
• Identity: 142/507 - (28%)
• Similarity: 241/507 - (47%)
• Gaps: 74/507 - (14%)

  Fly    19 KPYQAIPGPRGPFGMGNLYNYLPGIGSYSWLRLHQAGQDKYEK-YGAIVRETIVPGQ-DIVWLYD 81
            |.::.:|||.   .:.|||.|.  :..| .|..|:. |..|:| ||.:.|..|  |: .:|.:.|
 Frog    84 KEFEDLPGPS---LLKNLYYYF--LRGY-LLHTHEL-QLIYKKMYGPLWRSEI--GKYKMVNIAD 139

  Fly    82 PKDI-ALLLNERDCPQRRSHLALAQYRKSRPDVYKTTGLLPTNGPEWWRIRAQVQKELSAPKSVR 145
            |:.: .|:..|...|.|........:|..|...|   |.....|.:|::||:.:.|::..|....
 Frog   140 PEVLQRLVRQEGKYPMRNKEDVWKAHRDKRKLAY---GPFTEEGHQWYQIRSALNKKMLKPSEAA 201

  Fly   146 NFVRQVDGVTKEFIRFLQESR----NGGAI-DMLPKLTRLNLELTCLLTFGARLQSFTAQEQDPR 205
            ::...::.|..:|:..||:.|    :|..: |:...|.|...|....:.|..|:...  .:|.|
 Frog   202 SYAGGINEVVTDFMDRLQDMRKASPSGDMVNDLANALYRFAFEGISNIVFETRIGCL--DKQIP- 263

  Fly   206 SRSTRLMDAA--ETTNSC-----------ILP-TDQGLQLW----RFLETPSFRKLSQAQSYMES 252
            ..:.:.:|:.  ...||.           ||| .|..::.|    .|.:....:|:|:.||.::
 Frog   264 PETQKFIDSIGYMFKNSVYVTFLPHWTRGILPYWDHYIEGWDNIFDFGKHLIDKKMSEIQSRLD- 327

  Fly   253 VALELVEENVRNGSVGSSLISAYVKNPELDRSDVVGTAADLLLAGIDTTSYASAFLLYHIARNPE 317
                      :...|....::..:.:..|...:|.|:..:|||||:||||....:.:||:||:||
 Frog   328 ----------KGEEVEGEYLTYLLSSANLTMGEVYGSVCELLLAGVDTTSNTLCWAMYHLARDPE 382

  Fly   318 VQQKLHEEARRV-----LPSAKDELSMDALRTDITYTRAVLKESLRLNPIAVGVGRILNQDAIFS 377
            :||.::||....     :|.|:|..:|..|       |.|:||:|||.|:.....||:::..:..
 Frog   383 LQQAVYEEVSSAAPMDRIPVAEDIPNMPLL-------RGVIKETLRLYPVIPTNARIVSEKEVEI 440

  Fly   378 G-YFVPKGTTVVTQNMVACRLEQHFQDPLRFQPDRWL-----QHRSALNPYLVLPFGHGMRACIA 436
            | |..||.|..|..:....|.|::|:|||:|:|.|||     :|    :|:..:|||:|:|||:.
 Frog   441 GEYRFPKNTLFVLSHYAIARDEENFEDPLKFKPQRWLRDGGMKH----HPFSSIPFGYGVRACLG 501

  Fly   437 RRLAEQNMHILLLRLLREYELIWSGSDDEMGVKTLLINKPDAPVLIDLRLRR 488
            :|:||..||:.|.|::|.:||.|....:::.....::..|..||.:....|:
 Frog   502 KRIAELEMHLALSRVIRMFELRWDPKGEDIKSIARIVLSPSKPVNLQFLERK 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dib	NP_524810.2	CYP24A1-like	59..480	CDD:410677	127/457 (28%)
cyp27a1	XP_002933986.3	CYP27A1	118..547	CDD:410739	128/458 (28%)