Protein Alignment cv-2 and bmper

DIOPT Version :10

• Sequence 1: NP_524809.2
• Gene: cv-2 / 45280
• FlyBaseID: FBgn0000395
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_012820269.2
• Gene: bmper / 733449
• XenbaseID: XB-GENE-480927
• Length: 741
• Species: Xenopus tropicalis
• Alignment Length: 684
• Identity: 235/684 - (34%)
• Similarity: 328/684 - (47%)
• Gaps: 97/684 - (14%)

  Fly     3 CQSSGQWKFPAQQPRKSLASRRRHTGFRPST---QLLILIAVLLALLQGRTVDAGAGDSLSGVRQ 64
            |.|:|:...|.......:          |.|   .:|:|..|:...|        |...|:|...
 Frog    58 CPSTGKCLLPMSLTFSEI----------PITFIGWILVLSTVVRMSL--------ASSFLTGSIA 104

  Fly    65 SCSNEGEEVQ---LKNQPQIFTCFKCECQNGFVNC-RDTCPPVN-DCYILDKSNGTCCRRCKGCS 124
            .|.||||.:|   :.:.|    |..|.|.|..|.| |:.||.:: ||.::.|..|.||.|||||:
 Frog   105 KCENEGEALQIPFITDNP----CISCVCLNKEVTCKREKCPVLSKDCALVVKQRGACCERCKGCN 165

  Fly   125 FRGMSYESGSEWNDPEDPCKTYKCVATVVTETIQKCYSQCDNNQLQPPRPGECCPTCQGCKINGQ 189
            ::|..|.|..:|.|...||.|.:|...|:||:..:|...|.|.|.|   .|.|||||.||...|:
 Frog   166 YQGSHYNSSMKWRDSVQPCITRQCQEGVITESEVQCLVHCRNPQRQ---SGLCCPTCPGCIYEGR 227

  Fly   190 TVAEGHEVDASIDDRCLVCQCRGTQLTCSKKTCPVLPCPMSKQIKRPDECCPRCPQNHSFLPVP- 253
            ...||.|.... .::||.|.|.|.:..|.|:.||:|.||.........:|||:|........:|
 Frog   228 QYKEGDEFQPE-GNKCLKCSCIGGRTQCIKEVCPILSCPQHLSHIPTGQCCPKCIGQRKVFDLPS 291

  Fly   254 GKCLFNKSVYPEKTQFMPDRCTNCTCLNGTSVCQRPTCPILECAPEFQEPDGCCPRCAVAEVRSE 318
            |.|||...||...:.||.||||.|:|.:.|.||:|...|:..|.   ::.:.||..| |:.|.:|
 Frog   292 GSCLFRSDVYDNHSTFMYDRCTTCSCKDSTVVCKRKCSPVGTCN---RDKEQCCEDC-VSHVMAE 352

  Fly   319 ----CSLDGIVYQNNETWDMGPCRSCRCNGGTIRCAQMRC-PAVKCRANEELKQPPGE------C 372
                |.....::::.|.|....|..|.|..|...|.:.:| |...|        |.|:      |
 Frog   353 EVKICKSGSKIFRDGEMWSSFNCTICSCVKGKTECRKKQCIPVNSC--------PQGKILNRKGC 409

  Fly   373 CQRCVETAGTCTVFGDPHFRTFDGKFFSFQGSCKYLLASDCMGKT--FHIRLTNEGRGTRRASWA 435
            |..|.|..|.||||||||:.||||:.|:|||:|:|:|..||...|  |.:.:.|:.|.|...||.
 Frog   410 CPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSSTSSFQVLVKNDARRTHSFSWT 474

  Fly   436 KTVTLSLRNLKVNLGQRMRVKVNGTRVTLPYFVVAGGQNVTIERLANGGAVMLRSEMGLTLEWNG 500
            |:|.|.:....::|.|.:.||.||||::|||      :........:|..:.:.::.||.:.|:|
 Frog   475 KSVDLIMGESSISLQQHLTVKWNGTRISLPY------ETPQFHIDLDGYLLKVTTKAGLEISWDG 533

  Fly   501 AGFLQVSVPAKFKKRLCGLCGNFNGSSRDDLTGKDGRSHGDDEVWHFANSWKVGGPKSCSRKRE- 564
            ..|::|......|.:|||||||:||..||||.|.||....|  |..|.:||:|...:.|:|.:.
 Frog   534 DSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGSDGDFKFD--VDDFGDSWRVESNEFCNRPQRK 596

  Fly   565 ------------FLAATPTCDKRKS-NFY-CHPLSVPALFGECNERLNPENYKAACRMDVCECP- 614
                        .|.|...|.|.|| :|. ||.....|:|           |: :|..|:||||
 Frog   597 TIPELCQGTVKVKLRAHRECQKLKSWDFQNCHSTVDYAMF-----------YR-SCVTDMCECPV 649

  Fly   615 SGDCHCDSFAAYAHECRRLGVQLPDWRSATNCPA 648
            ..:|:|:|..|||..|.|.||:: .|:....|.|
 Frog   650 HKNCYCESLIAYARACLREGVKV-HWKPEHTCAA 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cv-2	NP_524809.2	VWC	184..243	CDD:214564	20/58 (34%)
		VWC	256..310	CDD:278520	21/53 (40%)
		VWC	319..376	CDD:214564	15/63 (24%)
		VWD	371..536	CDD:214566	69/172 (40%)
		C8	580..646	CDD:462584	22/67 (33%)
bmper	XP_012820269.2	VWC	222..280	CDD:278520	20/58 (34%)
		VWC	357..413	CDD:450195	15/63 (24%)
		VWD	420..569	CDD:459671	64/154 (42%)
		C8	616..680	CDD:462584	27/76 (36%)
		TIL	685..738	CDD:410995