Protein Alignment cv-2 and Muc5ac

DIOPT Version :10

• Sequence 1: NP_524809.2
• Gene: cv-2 / 45280
• FlyBaseID: FBgn0000395
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_063129851.1
• Gene: Muc5ac / 682837
• RGDID: 62001
• Length: 3922
• Species: Rattus norvegicus
• Alignment Length: 750
• Identity: 180/750 - (24%)
• Similarity: 263/750 - (35%)
• Gaps: 242/750 - (32%)

  Fly    27 TGFRPSTQLLI-----------------LIAVLLA-----LLQG-----RTVDAGAGDSLSGVRQ 64
            |.|||||..:|                 .::|.:|     |..|     .::.|....::|||.:
  Rat   529 TFFRPSTFFIIGQTNLGLQLEIQLHPIMQVSVRIAPEFRGLTSGLCGNFNSMQADDFQTISGVVE 593

  Fly    65 SCSNEGEEVQLKNQPQIFTCFKCECQNGFVNCRDTCPPVNDCYILDKSNGTCCRRCKGCSFRGMS 129
            ..:           ...|..||.:.         .||.|.:.:.            ..||....:
  Rat   594 GTA-----------AAFFNTFKTQA---------ACPNVKNIFE------------DPCSLSVEN 626

  Fly   130 YESGSEW----NDPEDPCKTYKCVATVVTET-IQKC-YSQCDNNQLQPPRPGECCPTCQGCKING 188
            .:....|    .|...|..  :|.|||...| ...| :..|:            |...:.|
  Rat   627 EKYAQHWCSQLTDANGPFS--QCHATVNPSTFFSNCMFDTCN------------CEKSEDC---- 673

  Fly   189 QTVAEGHEVDASIDDRCLVCQCRGTQLT------CSKK--TCP--------VLPC-PMSKQIKRP 236
                    :.|::......|..:|..|:      |.|.  |||        :..| |..:.:...
  Rat   674 --------LCAALSSYVRACAAKGVLLSDWREGICEKPTITCPKSMTYQYHISTCQPTCRSLSEE 730

  Fly   237 DECCP---------RCPQNHSFLPVPGKCL--------FNKSVYPEKTQFMPDRCTNCTCLNG-- 282
            |..|.         .||:. :||...|||:        :..|..| ..:.:.|....|||..|
  Rat   731 DVTCHVNFIPVDGCTCPKG-TFLDDSGKCVQATSCPCYYKGSPVP-NGESVHDNGAICTCTQGAL 793

  Fly   283 --------TSVCQRP---------------------------TCPILECAPEFQEPDGC-CPR-- 309
                    |.||..|                           ||...||.|      || ||.
  Rat   794 TCIGGPVLTPVCDAPMIYFDCRNATPGDTGAGCQKSCHTLDMTCYSSECVP------GCVCPNGL 852

  Fly   310 -------CAVAEVRSECSLDGIVYQNNETWDMGPCRSCRCNGGTIRCAQMRCPAVKCRANEELKQ 367
                   |.||| ...|..:...|:..||..:| |.:|.|.....:|....|.|
  Rat   853 VADGNGSCVVAE-DCPCVHNEATYRPGETIQVG-CNNCTCENRMWQCTDKPCLA----------- 904

  Fly   368 PPGECCQRCVETAGTCTVFGDPHFRTFDGKFFSFQGSCKY-LLASDCMGK-----TFHIRLTNEG 426
                          ||.|:||.|:.||||:.:||.|.|:| ||..:|.|.     .|.:...|..
  Rat   905 --------------TCAVYGDGHYITFDGQRYSFSGDCEYTLLQDNCGGNGSSQDAFRVVTENIP 955

  Fly   427 RGTRRASWAKTVTLSLRNLKVNLG-QRMRVKVNGTRVTLPYFVVAGGQNVTIERLANGGAVMLRS 490
            .||...:.:|.:.:.|.:.::.|. .:|.|...|.....||||...|..:.:|           :
  Rat   956 CGTTGTTCSKGIKIFLGSYELKLSDSKMEVVQKGVGQEPPYFVHQMGNYLVVE-----------T 1009

  Fly   491 EMGLTLEWNGAGFLQVSVPAKFKKRLCGLCGNFNGSSRDDLTGKDGRSHGDDEVWHFANSWKVGG 555
            ::||.|.|:....:.:.:..:||.::|||||||:.::.:|.|.:......|  :..|.||||:.
  Rat  1010 DIGLVLLWDKKTSIFLRLSPEFKGKVCGLCGNFDDNAINDFTTRSQSVVSD--MLEFGNSWKLS- 1071

  Fly   556 PKSC---SRKREFLAATPTCDKRKS--NFYCHPLSVPALFGECNERLNPENYKAACRMDVCECPS 615
             .||   |..::...|.|   .|||  ...|..:: .|.|..|:..:.|..|..||..|.|.|.|
  Rat  1072 -PSCPDASVSKDPCTANP---YRKSWAQKQCSIIN-SATFSACHAHVEPAKYYEACVNDACACDS 1131

  Fly   616 G---DCHCDSFAAYAHECRRLGVQLPDWRSATNCP 647
            |   :|.|.:.||||..|..:||.: .||:...||
  Rat  1132 GGDCECFCTAVAAYAQACHEVGVCV-SWRTPDICP 1165

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cv-2	NP_524809.2	VWC	184..243	CDD:214564	14/84 (17%)
		VWC	256..310	CDD:278520	21/108 (19%)
		VWC	319..376	CDD:214564	11/56 (20%)
		VWD	371..536	CDD:214566	50/171 (29%)
		C8	580..646	CDD:462584	24/68 (35%)
Muc5ac	XP_063129851.1	None