Protein Alignment cv-2 and si:dkey-65b12.6

DIOPT Version :10

• Sequence 1: NP_524809.2
• Gene: cv-2 / 45280
• FlyBaseID: FBgn0000395
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_017211774.3
• Gene: si:dkey-65b12.6 / 569718
• ZFINID: ZDB-GENE-060526-329
• Length: 4571
• Species: Danio rerio
• Alignment Length: 629
• Identity: 162/629 - (25%)
• Similarity: 250/629 - (39%)
• Gaps: 141/629 - (22%)

  Fly    93 FVNCRDTCPP---VNDCYILDKSNGT----CCRRCK----GCSFRGMSYESGSEWNDPEDPCKTY 146
            |.:|.|..||   .:|| :.|.:..|    .||..:    .|...|:|.   :.|.:      |.
Zfish  2329 FSSCYDKIPPQKYFDDC-VKDVAQATDKTAHCRHIQNYVASCQAIGISI---NIWRN------TT 2383

  Fly   147 KCVAT--------VVTETIQKCYSQCDNNQLQPPRPGECCPTCQ-GCKINGQTVAEGHEVDASID 202
            .|..|        :.|:|   |.|.|.:     ....:.||.|| ||:.:...:.:|.|..|..|
Zfish  2384 FCPLTCFKNSHYELCTDT---CSSTCAS-----LTKSQRCPLCQEGCQCDDGFLFDGGECKALQD 2440

  Fly   203 DRC-------------LVCQCRGTQLTCSKK--TCPVLPCPMSKQIKRPDECCP------RCPQN 246
            ..|             ::.:|:.| .||:..  ||..:.|       :.:|.|.      .|...
Zfish  2441 CGCHVDGTFYKSGEAVVLGECKET-CTCTAGVFTCVPMEC-------KKEEICDIKEGAVGCYSK 2497

  Fly   247 HSFLPVPGKCLFNKSVYPEKTQFMPDRC-TNC--TCLN--GTSVCQRPTCPILECAPEF-QEPDG 305
            .::.||               ....:.| |.|  ||.|  |...|..|.....:|...| :..|.
Zfish  2498 KTYCPV---------------NMHYEACGTACAPTCANRDGPEKCALPCVEGCQCNAGFVRSGDE 2547

  Fly   306 CCP--RCAVAEVRSECSLDGIVYQNNET-WDMGPC-RSCRCNG--GTIRCAQMRC-PAVKCRANE 363
            |.|  :|.       |:..|..|...:| |....| ..|.||.  |.:.||..:| .::.|....
Zfish  2548 CIPVKQCG-------CAYKGQYYLPGQTFWGEKQCTEKCVCNSQTGNVECAPAKCMNSLVCGVRN 2605

  Fly   364 ELKQPPGECCQRCVETA-GTCTVFGDPHFRTFDGKFFSFQGSCKYLLA-----SDCMGKTFHIRL 422
            .:|.        |...: .||...|||||||||||.|.|||:|.|.|:     :|.....|.:.:
Zfish  2606 GVKD--------CYPLSYSTCQGAGDPHFRTFDGKAFDFQGTCTYYLSKLLNTADPTLIPFEVLV 2662

  Fly   423 TNEGRGTRRA-SWAKTVTLSLRNLKVNLGQRM--RVKVNGTRVTLPYFVVAGGQNVTIERLANGG 484
            .||.||...| ::.|:|:|::....:.|.:..  :||||...|.||:.:..|..::    ..:|.
Zfish  2663 KNENRGRNLAVAYTKSVSLTVYGYTIVLSKESPGKVKVNDLFVKLPFELEDGRLSI----FYSGY 2723

  Fly   485 AVMLRSEMGLTLEWNGAGFLQVSVPAKFKKRLCGLCGNFNGSSRDDLTGKDGRSHGDDEVWHFAN 549
            ..|::::.||||::|....:.:::|:.:...|.|||||:|.:..|:....:........:  |..
Zfish  2724 FGMIKTDFGLTLKFNWDSHVALTLPSTYYGVLGGLCGNWNDNINDEFLTPNNTLAATASI--FGT 2786

  Fly   550 SWKV----GGPKSCSRKREFLAATPTCD--KRKSNFYCHPLS----VPALFGECNERLNPENYKA 604
            ||||    |...:|..|     |.|.||  :|..:.:..|.|    ....|..|:.::||..:..
Zfish  2787 SWKVQDDPGCSDACQGK-----ACPKCDVAERNKDTFTKPCSKITDKQGPFKGCHSKVNPNQFYE 2846

  Fly   605 ACRMDVCECPS-GDCHCDSFAAYAHECRRLGVQLPDWRSATNCP 647
            .|..|:|.... ....|.:..||...|:.....:..||:.:.||
Zfish  2847 DCVYDMCMYGGHSTALCSALTAYTAACQHALGTVESWRTDSFCP 2890

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cv-2	NP_524809.2	VWC	184..243	CDD:214564	15/79 (19%)
		VWC	256..310	CDD:278520	14/61 (23%)
		VWC	319..376	CDD:214564	15/61 (25%)
		VWD	371..536	CDD:214566	56/173 (32%)
		C8	580..646	CDD:462584	15/70 (21%)
si:dkey-65b12.6	XP_017211774.3	None