Protein Alignment cv-2 and otogl

DIOPT Version :10

• Sequence 1: NP_524809.2
• Gene: cv-2 / 45280
• FlyBaseID: FBgn0000395
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_073786321.1
• Gene: otogl / 555569
• ZFINID: ZDB-GENE-050419-93
• Length: 2569
• Species: Danio rerio
• Alignment Length: 695
• Identity: 159/695 - (22%)
• Similarity: 233/695 - (33%)
• Gaps: 214/695 - (30%)

  Fly   100 CPPVNDCYILDKSNGTCCRRCKGCSFRGMSYESGSEWNDPEDPCKTYKCVATVVTETIQKCYSQC 164
            ||.|:|.:     .|.|                 |..:|.:|..:  ||.|.:....| .|:...
Zfish   296 CPEVDDDF-----PGPC-----------------SSESDMDDAIE--KCSALLFFPFI-SCHENI 335

  Fly   165 DNNQLQPPRPGECCPTCQGCKINGQTVAEGHEVDASIDDRCLVCQCRGTQLTCSKKTCPVLPCPM 229
            |.|           |....| ::...|::..|.           .||  .|....:.|..:..|:
Zfish   336 DPN-----------PFVVSC-VSDMCVSDDEET-----------FCR--TLVEYTRACSHVGYPV 375

  Fly   230 SKQIKRPDECCPRCPQNHSFLP------VPGKCLFNKSVYPEKTQFMPDRC--TNCTCLNGTSVC 286
            .:.......|..||  ..||:.      .|..|.|:|            .|  ||..||:|   |
Zfish   376 REWRDSFPTCADRC--EDSFVHRDCISCCPPTCTFDK------------ECLGTNLHCLDG---C 423

  Fly   287 QRPTCPILECAPEFQEPDGCCPRCAVAEVRSECSLDGIVYQNNETWDMGPCRSCRCNGGTIRCAQ 351
            ..|...||:        :|.|    :|..:..|...|..|......:.| |..|.|.||...|.:
Zfish   424 YCPDGLILQ--------NGTC----IAVSQCPCVYHGTAYPLGHVLEQG-CTVCVCMGGLWNCTE 475

  Fly   352 MRCPAVKCRANEELKQPPGECCQRCVETAGTCTVFGDPHFRTFDGKFFSFQGSCKYLLASDCMGK 416
            ..|.|                         .|||.||.|..||||:.:...|||:|:|.......
Zfish   476 NNCTA-------------------------ECTVVGDTHVTTFDGRIYMHLGSCQYVLVKSRGNT 515

  Fly   417 TFHIRLTNEGRGTRR-------------ASWAKTVTLSLRNLKVNLGQRMRVKVNGTRVTLPYFV 468
            .|.:.|.....|..:             ...::.|||: |:.:|.:|..|       .|.|||
Zfish   516 KFTVTLQYTACGESQEHSCIHSVALVVDEDVSRQVTLT-RDGEVVIGASM-------AVNLPY-- 570

  Fly   469 VAGGQNVTIERLANGGAVMLRSEMGLTL--EWNGAGFLQVSVPAKFKKRLCGLCGNFNGSSRDDL 531
              ..:.|.:.||.: ..|.|||..||..  :|.| |.:.:.:.:.:.....||||..||:.|||.
Zfish   571 --SDETVNVRRLTS-LFVGLRSVFGLRFQYDWQG-GRIYLQLDSTWMGSTLGLCGTLNGNLRDDF 631

  Fly   532 TGKDGRSHGDDEVWHFANSWKVGGPKSCSRKREFLAATPTCDKRKSN-FY---CHPLSVPALFGE 592
            ....|...|..::  ..|:|||.  .:|..........| |:..:.| ||   |..| :..:|..
Zfish   632 LSPAGMIEGTPQL--HVNAWKVS--SACISPVNIPIIDP-CEMNQQNVFYAAQCDVL-LEEVFRP 690

  Fly   593 CNERLNPENYKAACRMDVCECPSGDCHCDSFAAYAHECRRLGVQL-------------------- 637
            |:..::|..|...||...|.|.| .|.|.:.:.||:.|.:..|.:
Zfish   691 CHAYVSPSMYHQQCRYQACRCGS-SCLCTALSHYAYICSKHHVTINFRAHVSECGMVCLGGMMYH 754

  Fly   638 --------------------PDWRSATNCPAG-----WRRNATLSS-----FKGNQFY-GDPSFS 671
                                .|.....:|..|     .|:...|.|     |.|:.|. |:.|||
Zfish   755 PCTSACGRTCQSVSSAEVCDGDCAEGCSCTEGTFYDHTRQRCVLLSQCHCYFMGSVFQPGEVSFS 819

  Fly   672 RMKGRRQKNHQLRLQLQQEQQQR----------SKQGQKGRHKPG 706
            .......:|.::....::.:.:|          |.:||.||...|
Zfish   820 SSGPCLCRNGRMECVPEEREPERGDCPNGKVYYSCRGQSGRGPSG 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cv-2	NP_524809.2	VWC	184..243	CDD:214564	9/58 (16%)
		VWC	256..310	CDD:278520	15/55 (27%)
		VWC	319..376	CDD:214564	12/56 (21%)
		VWD	371..536	CDD:214566	50/179 (28%)
		C8	580..646	CDD:462584	19/108 (18%)
otogl	XP_073786321.1	None