DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cv-2 and zgc:113531

DIOPT Version :9

Sequence 1:	NP_524809.2	Gene:	cv-2 / 45280	FlyBaseID:	FBgn0000395	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_001013504.1	Gene:	zgc:113531 / 541359	ZFINID:	ZDB-GENE-050320-52	Length:	217	Species:	Danio rerio

Alignment Length:	201	Identity:	51/201 - (25%)
Similarity:	77/201 - (38%)	Gaps:	40/201 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 CKINGQT--VAEGHEVDASIDDRCLVCQCRGTQLTCSKKTCPVLPCPMSKQIKRPDECCPRCPQN 246
            |:.||..  |.|.:.:|:   |.|..|:|......|::..|..||.........|.:|||||.:.
Zfish    37 CEANGSVYYVGEWYFLDS---DPCTQCECTADGSACARTECTSLPTACIHVSHYPTDCCPRCEKI 98

  Fly   247 HSFLPVPGKCLFNKSVYPEKTQFMPDRCTNCTCL-NGTSVCQRPTCPILECAPEFQEPDGCCPRC 310
                    .|.:...||.....|.|..|..|||. :|.:.||...|....|.....:...|||:|
Zfish    99 --------GCEYGGEVYELGQHFQPSACEQCTCYSDGIAHCQVADCAPPPCVDPVYQKGECCPQC 155

  Fly   311 A------VAEVRSECSLDGIVYQNNETWDMGPCRSCRCN---------GGTI-RCAQMRCPAVKC 359
            .      |...|::     ::......| :..|..|||:         |..: .|:::|    .|
Zfish   156 KDGPNCYVNASRTQ-----VIPGGESVW-VDSCTKCRCHDIQDAGYWEGNRLAMCSRIR----NC 210

  Fly   360 RANEEL 365
            :.:|.|
Zfish   211 QPDEGL 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cv-2	NP_524809.2	VWC	184..243	CDD:214564	18/60 (30%)
		VWC	256..310	CDD:278520	17/54 (31%)
		VWC	319..376	CDD:214564	11/57 (19%)
		VWD	371..536	CDD:214566
		C8	580..646	CDD:285899
zgc:113531	NP_001013504.1	VWC	100..155	CDD:214564	17/54 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	2	1.870