DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cv-2 and tnc

DIOPT Version :9

Sequence 1:	NP_524809.2	Gene:	cv-2 / 45280	FlyBaseID:	FBgn0000395	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_001247300.1	Gene:	tnc / 42990	FlyBaseID:	FBgn0039257	Length:	2819	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	68/275 - (24%)
Similarity:	94/275 - (34%)	Gaps:	81/275 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 QGCKINGQTVAEGHEVDASIDDRCLVCQCRGTQLTCSKKTCPVLPCPMSKQI-------KRPDEC 239
            :||..|.....||..:  ..::.||.|.|....|.|..:.     ||.:|.|       ||.|:|
  Fly    45 EGCYYNYAHYQEGDRI--MTNEPCLNCTCHNRMLMCYLRV-----CPFTKPIGHDCIVEKREDQC 102

  Fly   240 CP--RCPQ------NHSFLPVPGK---------CLFNKSVYPEKTQF--MPDR-CTNCTCLNGTS 284
            ||  .||:      .||  |.||.         |...:..|||..|.  .|:: |..|.|:|..:
  Fly   103 CPIITCPEVPVDVPYHS--PEPGTELSIPEKFGCSIEEKFYPEGAQVPSNPNKPCELCYCINNQT 165

  Fly   285 VC--QRPTCPILECAPEFQEPDGCCP---RC---------------AVAEVR------------- 316
            .|  |..|..:..|.|.:.: ..|||   .|               ....||
  Fly   166 KCVMQECTLHVDGCLPIYNK-GSCCPVRYSCDHENELDFMDQSTTTTTTTVRPTTGFILASTMTP 229

  Fly   317 ---SECSLDGIVYQNNETW-DMGPCRSCRCNGGTIRCAQMRCPAVKCRAN----EELKQPPGECC 373
               ::|..||.::.:..:. ....|..|.|..|.|.||...|......||    ..:....||||
  Fly   230 PTTTDCIHDGEIFADGASLKGKNACEHCYCMRGDIVCAVQECEVPMMAANGKSCRAMPAAEGECC 294

  Fly   374 QR---CVETAGTCTV 385
            ..   |.:.:.|..:
  Fly   295 PSNYVCEDDSSTTEI 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cv-2	NP_524809.2	VWC	184..243	CDD:214564	20/67 (30%)
		VWC	256..310	CDD:278520	18/61 (30%)
		VWC	319..376	CDD:214564	17/64 (27%)
		VWD	371..536	CDD:214566	5/18 (28%)
		C8	580..646	CDD:285899
tnc	NP_001247300.1	VWC	235..296	CDD:214564	17/60 (28%)
		PHA02664	<433..595	CDD:177447
		Ehrlichia_rpt	529..1065	CDD:118064
		DUF863	<1684..>1788	CDD:283539
		VWC	2762..>2805	CDD:302663
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR46698
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100