Protein Alignment cv-2 and bmper

DIOPT Version :9

• Sequence 1: NP_524809.2
• Gene: cv-2 / 45280
• FlyBaseID: FBgn0000395
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001018323.2
• Gene: bmper / 338246
• ZFINID: ZDB-GENE-030219-146
• Length: 668
• Species: Danio rerio
• Alignment Length: 615
• Identity: 217/615 - (35%)
• Similarity: 302/615 - (49%)
• Gaps: 63/615 - (10%)

  Fly    59 LSGVRQSCSNEGEEVQLKN---QPQIFTCFKCECQNGFVNCR-DTCPPV-NDCYILDKSNGTCCR 118
            ::|...||.||||.:.:.|   .|    |..|.|.|....|: :.|.|: .||.::.|..|.||.
Zfish    29 ITGTEASCENEGEVLHIPNITDNP----CISCVCLNQKAECKQEKCAPLAEDCALVVKQTGACCE 89

  Fly   119 RCKGCSFRGMSYESGSEWNDPEDPCKTYKCVATVVTETIQKCYSQCDNNQLQPPRPGECCPTCQG 183
            :||||..:|.||.|...|..|..||.||.|...|:||...:|...|.|.::.|.:   |||||.|
Zfish    90 KCKGCLLKGTSYNSSHHWISPVKPCVTYSCQEGVITEAEMRCVIHCKNPKIHPKK---CCPTCPG 151

  Fly   184 CKINGQTVAEGHEVDASIDDRCLVCQCRGTQLTCSKKTCPVLPCPMSKQIKRPDECCPRC-PQNH 247
            |...|....|..|.... .:.|:.|.|.|.|..|.|..||||.||.......|.:||||| .|..
Zfish   152 CIFEGNLYKEDEEFHPE-GNPCIKCVCTGGQSMCHKLVCPVLSCPSHLTHTPPGQCCPRCRGQRR 215

  Fly   248 SFLPVPGKCLFNKSVYPEKTQFMPDRCTNCTCLNGTSVCQRPTCPILECAPEFQEPDGCCPRCAV 312
            .|...||.|||:..||...:....|.||.|||::.|.:|::...|...|     ....||..|.
Zfish   216 VFDLSPGSCLFHSEVYENGSSISYDNCTTCTCVDSTVLCRKRCSPPGSC-----HGTACCEACQ- 274

  Fly   313 AEVRSE----CSLDGIVYQNNETWDMGPCRSCRCNGGTIRCAQMRC-PAVKCRANEELKQPPGEC 372
            :.::.|    |.:...:|::.:.|....|..|.|..|.|:|....| |...|.:|:.|.:.  .|
Zfish   275 SHLKMEDVKYCRVKSKIYRDGDRWSSVNCSLCTCVKGNIQCQPKICVPITSCPSNKILNRT--GC 337

  Fly   373 CQRCVETAGTCTVFGDPHFRTFDGKFFSFQGSCKYLLASDCM-GKTFHIRLTNEGRGTRRASWAK 436
            |..|.:..|.||||||||:.||||:.|:|||:|||:|..||. ..:|.:.:.|:.|.||..||.|
Zfish   338 CPVCTDKPGVCTVFGDPHYNTFDGRTFNFQGTCKYVLTKDCSPAASFTVLVKNDARRTRSFSWTK 402

  Fly   437 TVTLSLRNLKVNLGQRMRVKVNGTRVTLPYFVVAGGQNVTIERLANGGAVMLRSEMGLTLEWNGA 501
            :|.|....|.::|.|.:.|:.||||:.||:.  :.|.::.::    |..:.|.:..||.:.|:|.
Zfish   403 SVELHTSGLSISLHQHLTVRQNGTRIALPFH--STGVHIDLD----GYLLKLTTIAGLEITWDGD 461

  Fly   502 GFLQVSVPAKFKKRLCGLCGNFNGSSRDDLTGKDGRSHGD-DEVWHFANSWKVGGPKSCS----R 561
            ..::|......|.:|||||||:||..|||..|.||:...| ||:   |.||:|...:.|.    |
Zfish   462 SLVEVVAAPHLKGQLCGLCGNYNGQRRDDSLGGDGQFKFDVDEL---AESWRVEDNELCEVQNRR 523

  Fly   562 KREFLAATP---------TCDKRKSNFYCHPLSVPALFGECNERLNPENYKAACRMDVCECP-SG 616
            ...||.|..         ||.|.||          ..|.:|:..::..::..:|..|:|||| ..
Zfish   524 PTSFLCAGTVKVKLRAHRTCQKLKS----------WEFQKCHSAVDFTSFYKSCVTDMCECPVHK 578

  Fly   617 DCHCDSFAAYAHECRRLGVQLPDWRSATNC 646
            :|.|:||.||:..|.|.|:.: .||....|
Zfish   579 NCFCESFIAYSRACEREGIHV-HWRPELTC 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cv-2	NP_524809.2	VWC	184..243	CDD:214564	21/58 (36%)
		VWC	256..310	CDD:278520	17/53 (32%)
		VWC	319..376	CDD:214564	16/57 (28%)
		VWD	371..536	CDD:214566	68/165 (41%)
		C8	580..646	CDD:285899	19/66 (29%)
bmper	NP_001018323.2	VWC	152..210	CDD:278520	21/58 (36%)
		VWC	224..273	CDD:302663	17/53 (32%)
		VWC	285..341	CDD:302663	16/57 (28%)
		VWD	348..490	CDD:278521	61/147 (41%)
		C8	539..607	CDD:285899	24/78 (31%)
		TIL	612..665	CDD:280072

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	107	1.000	Domainoid score	I6473
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12494
Inparanoid	1	1.050	377	1.000	Inparanoid score	I2047
OMA	1	1.010	-	-		QHG47479
OrthoDB	1	1.010	-	-		D1104860at2759
OrthoFinder	1	1.000	-	-		FOG0006882
OrthoInspector	1	1.000	-	-		oto40674
orthoMCL	1	0.900	-	-		OOG6_106931
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5778
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.880