Protein Alignment cv-2 and Muc5b

DIOPT Version :10

• Sequence 1: NP_524809.2
• Gene: cv-2 / 45280
• FlyBaseID: FBgn0000395
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001414085.1
• Gene: Muc5b / 309114
• RGDID: 1561983
• Length: 3925
• Species: Rattus norvegicus
• Alignment Length: 839
• Identity: 203/839 - (24%)
• Similarity: 286/839 - (34%)
• Gaps: 281/839 - (33%)

  Fly    27 TGFRPSTQLLILIAVLLAL----------LQGRTVDAGAGD--SLSGV--------------RQS 65
            ||.:...||:..:.|.:.|          |.|......|.|  :||||              :.|
  Rat   536 TGLQLQVQLVPFMQVFVRLDRSYQGQMCGLCGNFNQNQADDFTALSGVVEGTGAAFSNTWKTQAS 600

  Fly    66 CSNE--------GEEVQLKNQPQIFTCFKCECQNGFVNCRDTCPPV---NDCYILDKSNGTCCRR 119
            |.|.        ...|:.:|..:.:.....|....|..|..|..||   ::| :.|..|......
  Rat   601 CPNSKNTYEDPCSYSVENENFAREWCSMLTESSGVFSACHATVSPVPFYSNC-LFDTCNCENSED 664

  Fly   120 C---------KGCSFRGMSYESGSEWNDPEDPCKTYKCVATVVTETIQKCYSQCDNNQLQPPRPG 175
            |         :.|:.:|:..   |.|..                   :.||...:|    .|:..
  Rat   665 CMCAALSSYVRACAAKGVLL---SGWRG-------------------KACYKYMNN----CPQTK 703

  Fly   176 E-------CCPTCQGCKINGQTVAEGHEVDASIDDRCLVCQCRGTQLTCSKKTCPV--LPCPMSK 231
            |       |.|||:...          |||                :|||....||  ..||...
  Rat   704 EYSYSVSTCQPTCRSLS----------EVD----------------VTCSIPFVPVDGCTCPEGT 742

  Fly   232 QIKRPDECCP--RCPQNHSFLPVPGKCLFNKSVYPEKTQFMPDRCTNCTCLNGTSVC-----QRP 289
            .:...|.|.|  .||           |.|:.:|.......| |....|:|.||...|     ||.
  Rat   743 FLNDKDHCVPVEECP-----------CYFHGTVVASGEVVM-DNGVVCSCTNGKLTCLGALMQRN 795

  Fly   290 TCPILECAPEFQEPDGCCPRCAVAEVRSECSLDGIVYQNNETWDMGPCRSCRC------------ 342
            .    ||.......|  |...:|.:..:||      .::..|.|: .|.|.:|
  Rat   796 K----ECQAPMVYLD--CNNASVGDHGAEC------LRSCHTLDV-DCFSTQCVSGCVCPSGLVA 847

  Fly   343 --NGGTIRCAQMRCPAVKCRANEELKQPPGEC----CQRCV-----------ETAGTCTVFGDPH 390
              |||.|  |:..||.|    :.|....|||.    |..|.           ...|.|..:||.|
  Rat   848 DGNGGCI--AEEDCPCV----HNEATYRPGEIIRVDCNNCTCRNRRWECTNQPCMGACVAYGDGH 906

  Fly   391 FRTFDGKFFSFQGSCKYLLASD-CMGK-----TFHIRLTNEGRGTRRASWAKTVTLSLRNLKVNL 449
            |.||||:.:.|:|:|:|.||.| |.|.     ||.|...|...||...:.:|.:.:.:.:.::.|
  Rat   907 FVTFDGERYIFEGNCEYTLAQDYCRGNTSTDGTFRIVTENVPCGTTGTTCSKAIKIFVESYELIL 971

  Fly   450 GQ-RMRVKVNGTRVTLPYFVVAGGQNVTIERLANGGAVMLRSEMGLTLEWNGAGFLQVSVPAKFK 513
            .: ..:|...|.....||.:...|..:.||         :||  |:.:.|:....:.|.:...:|
  Rat   972 HEGNFKVVARGPSGDPPYKIRYMGIFLVIE---------IRS--GIVVSWDRKTSVFVRLQQHYK 1025

  Fly   514 KRLCGLCGNFNGSSRDDLTGKDGRSHGDDEVWHFANSWKVGGPKSCSRKREFLAATPTC------ 572
            .|:|||||||:.::.:|.|.:.....||  |..|.||||.               :|:|
  Rat  1026 GRVCGLCGNFDDNAINDFTTRSQSVVGD--VLEFGNSWKF---------------SPSCPDAPVP 1073

  Fly   573 -DKRKSNFY--------CHPLSVPALFGECNERLNPENYKAACRMDVCECPSG---DCHCDSFAA 625
             |...:|.|        |..:: .|.|..|:.:::...|..||..|||.|.||   :|.|.:.||
  Rat  1074 KDPCIANPYRKSWAQKKCSIIN-SATFAACHSQVDSTKYYEACVHDVCACDSGGDCECFCTAVAA 1137

  Fly   626 YAHECRRLGVQLPDWRSATNCPAGWRRNATLSSFKGNQF--YGDPSFSRMKGRRQKNHQLRLQLQ 688
            ||..||.:||.| .||:...||.               |  |.:|            |.   |.:
  Rat  1138 YAQACRDVGVCL-SWRTPDICPL---------------FCDYYNP------------HG---QCE 1171

  Fly   689 QEQQQRSKQGQKGRHKPGGHNQLDRQGHNGLDKDQLQKEFILKHVPSSFLYPRAPDRTP 747
            ...|.......|....|.||..:|..|..|                   .||:.|...|
  Rat  1172 WHYQPCGAPCLKTCRNPSGHCLVDLPGLEG-------------------CYPQCPPSQP 1211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cv-2	NP_524809.2	VWC	184..243	CDD:214564	13/62 (21%)
		VWC	256..310	CDD:278520	16/58 (28%)
		VWC	319..376	CDD:214564	19/74 (26%)
		VWD	371..536	CDD:214566	53/186 (28%)
		C8	580..646	CDD:462584	27/76 (36%)
Muc5b	NP_001414085.1	None