DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cv-2 and cutl-23

DIOPT Version :9

Sequence 1:	NP_524809.2	Gene:	cv-2 / 45280	FlyBaseID:	FBgn0000395	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_001317785.1	Gene:	cutl-23 / 189610	WormBaseID:	WBGene00021343	Length:	773	Species:	Caenorhabditis elegans

Alignment Length:	201	Identity:	42/201 - (20%)
Similarity:	65/201 - (32%)	Gaps:	74/201 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   369 PGECCQRCVETAGTCTVFGDPHFRTFDGKFFSFQGSCKYLLASDCMGKTFHIRLTNEGRGTRRAS 433
            |.|.....|.|...|.||..|....|             :|.|.               |:.|..
Worm    32 PPEIVHTPVSTKPRCKVFAPPLDLVF-------------ILDSS---------------GSLRDK 68

  Fly   434 WAKTVTLSLRNLK-VNLGQRMRVKVNGTRVTLPYFVVAGGQNV--TIERLANGGAVM-----LRS 490
            :...:.:..|.|| |.:|:      ..|||.|..|  :|.|::  ..|:..:...::     ||.
Worm    69 FQDEIDIIRRILKHVTIGK------TATRVMLIQF--SGTQHLEFNFEKFTDREELLAALDVLRH 125

  Fly   491 EMGLT------------LEWNGAGFLQVSVPAKFKKRLCGLCGNFNGSSRDDLTGKDGRSHGDDE 543
            ..|:|            |:..|:|....:||     ::..|.             .|||:|...:
Worm   126 VSGITRIGGAFEFALQQLKTPGSGLRDGTVP-----KIVYLL-------------SDGRTHDFPK 172

  Fly   544 VWHFAN 549
            .|..|:
Worm   173 DWQMAD 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cv-2	NP_524809.2	VWC	184..243	CDD:214564
		VWC	256..310	CDD:278520
		VWC	319..376	CDD:214564	2/6 (33%)
		VWD	371..536	CDD:214566	35/184 (19%)
		C8	580..646	CDD:285899
cutl-23	NP_001317785.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900