DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cv-2 and R11G1.1

DIOPT Version :9

Sequence 1:	NP_524809.2	Gene:	cv-2 / 45280	FlyBaseID:	FBgn0000395	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_001361923.1	Gene:	R11G1.1 / 187815	WormBaseID:	WBGene00020010	Length:	1745	Species:	Caenorhabditis elegans

Alignment Length:	245	Identity:	52/245 - (21%)
Similarity:	72/245 - (29%)	Gaps:	111/245 - (45%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 CQNGFVNC-RDTCPPVN-------DCYILDKSNGTCCRRCKGCSFRGMSYESGSEWNDPEDPCKT 145
            |..|..:| ...|.|::       ||  :|.|:..|......|   |..|            |..
Worm    33 CMLGDYDCGLGQCVPISQFRDGKPDC--MDGSDEWCFIGQVSC---GPVY------------CAD 80

  Fly   146 YK----CVATVVTETIQKCYSQCDNNQLQPPRPGECCPTCQ----------GCKINGQTVAEGHE 196
            ||    |:.          |.:||.:..|.|    .|.|.:          .||..|:
Worm    81 YKDALPCIV----------YPKCDGSSKQLP----WCSTSKEKLCADETSFPCKGYGE------- 124

  Fly   197 VDASIDDRCLVCQCRGTQLTCSKKTCP---------VLPCPMSKQIKRPDECCPRCPQNHSFL-- 250
                    |::.:    .|...||.|.         |:|.          |...||.:|.|.|
Worm   125 --------CVLWE----WLLDGKKDCNDGSDEDENYVMPL----------EHAYRCARNQSGLYL 167

  Fly   251 --PVPGKCLFNKSVYPEKTQFMPDRCTNCTCLNGTSVCQRPTCPILECAP 298
              |||.....:.|:|.|                |.|:|.:|:...|...|
Worm   168 PKPVPPPPEDHPSLYVE----------------GCSMCSKPSTVTLPSNP 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cv-2	NP_524809.2	VWC	184..243	CDD:214564	11/67 (16%)
		VWC	256..310	CDD:278520	9/43 (21%)
		VWC	319..376	CDD:214564
		VWD	371..536	CDD:214566
		C8	580..646	CDD:285899
R11G1.1	NP_001361923.1	LDLa	32..64	CDD:197566	9/32 (28%)
		LDLa	113..145	CDD:238060	8/50 (16%)
		PHA03247	<268..594	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900