DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cv-2 and F19C6.3

DIOPT Version :9

Sequence 1:	NP_524809.2	Gene:	cv-2 / 45280	FlyBaseID:	FBgn0000395	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_509679.1	Gene:	F19C6.3 / 184675	WormBaseID:	WBGene00008952	Length:	429	Species:	Caenorhabditis elegans

Alignment Length:	287	Identity:	68/287 - (23%)
Similarity:	95/287 - (33%)	Gaps:	99/287 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 WNDPE-------------DPCK---TYKCVATVVTETIQKCY--SQCD-------NNQLQPPRPG 175
            |..||             ..||   ..|..|...||.|::.|  |..|       ...:|.|
Worm   149 WKGPEPTQFLIGSGWPIGQKCKHDGVKKKYADAYTEKIERNYEPSAIDAINEIFFETVVQVP--- 210

  Fly   176 ECCPTCQGCKINGQTVAEGHEVDASIDDRCLVCQC-RGTQLTCSKKTCPVLPC--PMSKQIKRPD 237
               |...|||||...:    .::.:....|..|.| ....:.|....||.:.|  ||.    |.|
Worm   211 ---PGFDGCKINNALL----NINETKTVNCNTCTCVDRDNVVCQAVDCPAVTCTHPMI----RKD 264

  Fly   238 ECCPRCPQNHSFLPVPGKCLF--NKSVYPEKTQFMPDRCTNCTCLNGT-------SVCQRPTCPI 293
            :|||.|.:         :|.:  :|...|....|.|..|..|.|.:..       :.|:.|:||.
Worm   265 DCCPSCGE---------QCFYESHKIANPHGEVFWPGDCYRCQCWDKKVHCSSEYATCEPPSCPE 320

  Fly   294 LECAPEFQEPDGCCPR-------CAVAEVRS-----------ECSLDGIVYQNNETW-------- 332
            .:..  :.|...|||:       |||.....           :||.| ..:|.|.|:
Worm   321 EDWV--YNEKFNCCPKCRDFARFCAVKPCHKYATCTDSKRGPKCSCD-TGFQGNGTYCEDIDECS 382

  Fly   333 -------DMGPCRS---CRCNGGTIRC 349
                   .:|.|.|   ||...|:.:|
Worm   383 FSQDAKEQLGGCLSGSTCRNVPGSYKC 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cv-2	NP_524809.2	VWC	184..243	CDD:214564	18/61 (30%)
		VWC	256..310	CDD:278520	16/69 (23%)
		VWC	319..376	CDD:214564	13/49 (27%)
		VWD	371..536	CDD:214566
		C8	580..646	CDD:285899
F19C6.3	NP_509679.1	VWC	216..270	CDD:214564	18/61 (30%)
		EGF_3	346..375	CDD:289699	6/29 (21%)
		EGF_CA	377..416	CDD:214542	7/33 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810