Protein Alignment cv-2 and Y8A9A.2

DIOPT Version :9

• Sequence 1: NP_524809.2
• Gene: cv-2 / 45280
• FlyBaseID: FBgn0000395
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001364778.1
• Gene: Y8A9A.2 / 173723
• WormBaseID: WBGene00021171
• Length: 1358
• Species: Caenorhabditis elegans
• Alignment Length: 880
• Identity: 165/880 - (18%)
• Similarity: 227/880 - (25%)
• Gaps: 350/880 - (39%)

  Fly     2 CCQSSGQW-KFPAQQPRKSLASRRRHTGFRPSTQLLILIAVLLALLQGRTVDAGAGDSLSGVRQS 65
            ||.|.|.| ::.|..|..:.........:|         .|.|.     ..|.||
 Worm   560 CCPSGGFWSEWTADAPCATTCGSCSQQVYR---------RVCLT-----EADCGA---------- 600

  Fly    66 CSNEGEEVQLKNQPQIFTCF--KCECQNGFVN--------C----RDTCPPVND--CYILD---- 110
            |:  |.:|:::| ..:..|:  ...|..|:..        |    ..|.|..||  |..||
 Worm   601 CT--GADVKIQN-CNVGVCYFPLDSCCAGYTATVSGTLHICGPQPTTTTPAPNDETCCPLDGIWG 662

  Fly   111 ------KSNGTCCRRCKG-------------CSFRGMSYE--------SGSEWNDP----EDPCK 144
                  ...||.|..|.|             ||..|.:.|        |.|||...    :..|.
 Worm   663 AWGEWSVCTGTTCGNCGGSRTRTRVCASDSFCSCNGDTTESENCRLLSSWSEWTTTGTCNQTACG 727

  Fly   145 TYKCVATVVTETIQK---CY-----SQCDNNQLQPPRPGECC------PTCQGCKINGQTVAEGH 195
            |  |.....|.|..|   |:     ::.|....:|...|..|      .|..|..|.|...|...
 Worm   728 T--CQTLTYTRTCLKTNGCFCMGSATKTDYCSRKPCATGTACCNSLTAQTVDGVSICGPVEAAED 790

  Fly   196 EVDA------------------------SIDDRC----------------LVCQCRGTQLTCSKK 220
            |.|.                        :.:|.|                ..|.|.|:  |..:.
 Worm   791 ETDPVPCTTTTPACCVLGGVWSEWSSGDACNDTCGNCGVTTLSRVCLSQDYNCACSGS--TTKQS 853

  Fly   221 TCPVLPCPMSK----------------QIKRPD------------ECCPRCPQNHSFLPVPGKCL 257
            .|...|||..:                :....|            :|||......|.....|.|
 Worm   854 ECAPAPCPFPRTSCCGARKKVIVGRTFECSSADDSDAAPSTLCAVDCCPAAGGYWSEWTTGGSC- 917

  Fly   258 FNKSVYPEKTQFMPDRCTNCTCLNGTSVCQRP-TCP------------ILEC------------- 296
                         |..|.:|:.:....||..| |||            |..|
 Worm   918 -------------PTTCGSCSTVTQKRVCMSPSTCPCQGVSSRSVNCGITVCYFPDDSCCAGYSA 969

  Fly   297 -----------APEFQEP---------DGCCPRCAVAEVRSECSLDGIVYQNNETWDMGP----- 336
                       .|.:..|         |.|||...:.                ..|...|
 Worm   970 TVSGTQHICGPQPNYTTPYAPYDPTCTDNCCPETGIW----------------SDWTSTPNQCRD 1018

  Fly   337 -CRSCRCNGGTIRCAQMR--CPAVKCRANEELKQPPG---------ECCQRCVETAGTCTVFGDP 389
             |.||.....|..|....  ||   |:....:.:|.|         .||     ...|.||.|:.
 Worm  1019 YCGSCGNQTRTRTCTSDADGCP---CQGPTTITEPCGTGVCYFPRLSCC-----PGYTATVEGNQ 1075

  Fly   390 HFRTFDGKFFSFQGSCKYLLASDCMGKTFHI----RLTNEGRGTRRAS--WAKTVTLS-LRNLKV 447
            |.                     |...|..:    :|...|.....::  |.:.|::| ..:...
 Worm  1076 HI---------------------CGPLTTAVADPDKLNTCGVSCCPSAGIWGEWVSVSGCNDTCG 1119

  Fly   448 NLGQRMRVKVNGTRVTLPYFVVAGGQNVTIERLANGGAVMLRSEMGLTLEWNGAGFLQVSVPAKF 512
            :.||..|.:   ..::|.|.....| |.|...:......:               |.:.|....|
 Worm  1120 SCGQETRKR---KCLSLQYGCACTG-NATDTSVCASSVCL---------------FPRTSCCTGF 1165

  Fly   513 KKRL--------CGLCGNFNGSSRDDLTGKDGRSHGDDEVWHFANSWKVGGPKSCSRKREFLAAT 569
            ||.:        ||........:.:..|..|....|   :|   |.|  |...:||      |..
 Worm  1166 KKMVNITGRTFYCGPLPVVPAFNPEQTTCCDPEKTG---LW---NDW--GAWTTCS------ATC 1216

  Fly   570 PTCDKRKSNFYC--HPLSVPALFGECNERLNPENYKAACRMDVCECPSGDCHCDSFAAYAHECRR 632
            ..|..:..:..|  .|...|.. |:..|       ..:|...|| .....|....|.|..::
 Worm  1217 GGCGTQTRSRTCASAPYGCPCT-GDLTE-------TQSCAKQVC-TTGAQCCAGKFVATGYD--- 1269

  Fly   633 LGVQLPDWRSATNCPAGWRRNATLSSFKGNQFYGD 667
             |.|.....:...|...|...|||.....|...|:
 Worm  1270 -GAQYCQDNTPEVCTGTWTEWATLEGAVCNDTCGN 1303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cv-2	NP_524809.2	VWC	184..243	CDD:214564	19/126 (15%)
		VWC	256..310	CDD:278520	18/99 (18%)
		VWC	319..376	CDD:214564	14/73 (19%)
		VWD	371..536	CDD:214566	30/179 (17%)
		C8	580..646	CDD:285899	13/67 (19%)
Y8A9A.2	NP_001364778.1	TSP1	1203..1252	CDD:214559	14/67 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900